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PAEA EOC 2026/2027 – Summative Practice Exam | 450 Questions with Answers | Physician Assistant Exam Prep | Graded A+

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This PAEA EOC 2026/2027 Summative Practice Guide provides 450 high-yield questions with correct answers and detailed rationales, designed for Physician Assistant students preparing for the PAEA End-of-Course (EOC) exam. Covering all core medical topics, clinical reasoning, and patient management scenarios, this guide allows learners to assess knowledge, reinforce concepts, and enhance test-taking skills. Fully graded for clarity, this comprehensive resource helps students aim for top performance and succeed on the PA EOC exam. Available as a ready-to-use PDF for convenient study anywhere. PAEA, Physician Assistant Exam, EOC Practice, Summative Exam, Test Prep, 450 Questions, Answers and Rationales, PA Exam Prep, Clinical Knowledge, Study Guide

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Uploaded on
November 28, 2025
Number of pages
39
Written in
2025/2026
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Exam (elaborations)
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PAEA EOC 2026/2027, PAEA Summative Practice, physician
assistant exam, EOC questions and answers, PAEA 450
questions, PA exam prep, graded A+


how should you educate a patient with AAA on exercise? - SELECTED ANSWER
👀 Patients should be counseled that moderate physical activity such as running,
biking, swimming, hiking, or sexual activity and activities such as gardening,
golfing, and horseback riding do not precipitate AAA rupture


Moderate physical therapy may also limit aneurysm expansion. In experimental
aneurysms, increased aortic blood flow appears to inhibit AAA expansion


However, heavy lifting, especially while holding the breath, and other activities
that lead to Valsalva transiently induce significant increases in blood pressure and
should be avoided


gold standard for dx renal artery stenosis? what can be used to monitor disease
progression? - SELECTED ANSWER 👀 renal arteriography


But really a spiral CT angiography is very useful and probably more likely done
first


duplex doppler US can be used to monitor disease progression


what are some symptoms of mitral valve prolapse syndrome? - SELECTED
ANSWER 👀 various nonspecific symptoms such as palpitations, dyspnea,
exercise intolerance, anxiety disorders, and dizziness

,since symptoms are relatively uncommon, what physical exam findings are
associated with mitral valve prolapse? - SELECTED ANSWER 👀 non-ejection
click in systole


click is mobile, meaning its timing varies with maneuvers that change the left
ventricular volume, occurring earlier in systole with sitting, standing, or other
interventions that reduce ventricular size, or later with those interventions that
increase chamber size such as squatting


People with MVP tend to have lower BMIs


how would you distinguish vasospastic angina and angina associated with CAD? -
SELECTED ANSWER 👀 quality of the CP is typically indistinguishable of the two


patients with vasospastic angina report that their episodes are predominantly at
rest and that many occur from midnight to early morning, while effort tolerance is
usually preserved. CP generally lasts 5 to 15 minutes


Patients with vasospastic angina are often younger and exhibit fewer classic
cardiovascular risk factors and may be associated with other vasospastic
disorders, such as Raynaud's phenomenon and migraine headache


Exercise does not usually provoke an episode of spasm


ECG may reveal transient ST-segment elevation or depression in multiple lead but
troponins will not be elevated

,where do karposi sarcoma lesions typically occur? describe their appearance. -
SELECTED ANSWER 👀 often on distal extremities, such as lower legs and feet


purplish, reddish blue, or dark brown/black macules, plaques, and nodules on the
skin. Nodular lesions may ulcerate and bleed easily


common in poorly controlled HIV


how would you treat hidradenitis suppurativa? - SELECTED ANSWER 👀 topical
clindamycin


if fail topical therapy, oral tetracyclines are suggested


Antiandrogenic drugs and metformin are additional treatment options that may
be used alone or in conjunction with antibiotic therapy


Pt with hypertriglyceridemia >885 mg/dL that required medical therapy due to no
improvement after lifestyle changes and statin. how would you treat? - SELECTED
ANSWER 👀 fenofibrate


fenofibrate is better than gemfibrozil bc can be used with a statin. Gemfibrozil has
a higher risk of muscle toxicity


how would you initially treat a pt with hypertriglyceridemia? - SELECTED
ANSWER 👀 lifestyle changes (reduce EtOH consumption, aerobic exercise,
better glycemic control) and statin

, what causes subacute thyroiditis? - SELECTED ANSWER 👀 presumed to be
caused by a viral infection or a postviral inflammatory process. Many patients
have a history of an upper respiratory infection prior to the onset of thyroiditis


seasonal incidence (higher in summer)


Large-needle thyroid biopsies reveal widespread infiltration with neutrophils,
lymphocytes, histiocytes and giant cells, disruption and collapse of thyroid
follicles, and necrosis of thyroid follicular cells


how is the diagnosis of subacute thyroiditis made? - SELECTED ANSWER 👀
clinical dx


neck pain, thyroid tenderness
suppressed TSH
T3/T4 mildly elevated


if clinical dx is not certain, US can be used to distinguish subacute from Graves.
Graves has increased flow and subacute has decreased flow. FNA rarely
needed/used


what is the first step in evaluation of a suspected thyroid nodule? - SELECTED
ANSWER 👀 US


Apparent nodularity in Hashimoto's thyroiditis may represent focal enlargement
from lymphocytic infiltrates, TSH-induced hyperplasia of follicular tissue, or a

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