NR 565 - ACTUAL
Advanced Pharmacology
midterm – Chamberlain
EXAM LATEST 2025-2026
WITH QUESTIONS AND
CORRECT VERIFIED
ANSWERS GRADED A+
CYP450 pneumonic - ANSWERS-"VISA credit card debt INHIBITS spending on
designers like CK to look GQ"
Inhibitors of what can lead to toxic levels of eplerenone? - ANSWERS-Inhibitors of
CYP3A4, increase levels of medication, risk for toxicity
MOST concerning adverse effects of eplerenone - ANSWERS-hyperkalemia
,adverse effects of CCBs in elderly patients - ANSWERS-gingival hyperplasia
(overgrowth of gum tissue) and chronic eczematous rash
verapamil increases the plasma level of what medication by 60%? - ANSWERS-digoxin
What should patients avoid taking with CCBs? - ANSWERS-grapefruit juice
(INHIBITOR)
Can nifedipine be used to treat dysrhythmias? - ANSWERS-No
Reflex tachycardia can occur with which CCB? - ANSWERS-Nifedipine
CYP450 inhibitors drug names - ANSWERS-Valproate, isoniazid, sulfonamides,
amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact pharmacodynamics and
pharmacokinetic properties of drugs? - ANSWERS-increase glomerular filtration rate
leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic - ANSWERS-Antiepileptic drugs,
antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in large doses,
some anticoagulants, and hormonal medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in neonates? - ANSWERS-
slow and erratic due to low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased in infancy? - ANSWERS-
delayed gastric emptying
Some medications that should be avoided in the pediatric patient? - ANSWERS-
glucocorticoids, discoloration of developing teeth with tetracyclines, and kernicterus with
sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration patient education? - ANSWERS-
dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
, What are some things that put the elderly patient at higher risk for adverse drug
reactions? - ANSWERS-reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
How can healthcare providers decrease likelihood of an elderly patient experiencing an
adverse drug reaction? - ANSWERS-obtaining a thorough drug history that includes
over-the-counter medications
considering pharmacokinetic and pharmacodynamics changes due to age
monitoring the patient's clinical response and plasma drug levels
using the simplest regimen possible
monitoring for drug-drug interactions and iatrogenic illness
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the Beers list
How can we promote medication adherence with elderly patients? - ANSWERS-
simplifying drug regimens
providing clear and concise verbal and written instructions
using an appropriate dosage form
clearly labeling and dispensing easy-to-open containers
developing daily reminders
monitoring frequently
affordability of drugs
support systems
Why do nitrates need to be taken no later than 4 PM? - ANSWERS-Need nitrate free
interval so tolerance doesn't develop
Nine factors that impact outcome of medication? - ANSWERS-Gender and race
Genetics and pharmacogenomics
Variability in absorption
placebo effect
Tolerance
patho
age
bodyweight
Do you need informed consent for genetic testing? - ANSWERS-yes
Advanced Pharmacology
midterm – Chamberlain
EXAM LATEST 2025-2026
WITH QUESTIONS AND
CORRECT VERIFIED
ANSWERS GRADED A+
CYP450 pneumonic - ANSWERS-"VISA credit card debt INHIBITS spending on
designers like CK to look GQ"
Inhibitors of what can lead to toxic levels of eplerenone? - ANSWERS-Inhibitors of
CYP3A4, increase levels of medication, risk for toxicity
MOST concerning adverse effects of eplerenone - ANSWERS-hyperkalemia
,adverse effects of CCBs in elderly patients - ANSWERS-gingival hyperplasia
(overgrowth of gum tissue) and chronic eczematous rash
verapamil increases the plasma level of what medication by 60%? - ANSWERS-digoxin
What should patients avoid taking with CCBs? - ANSWERS-grapefruit juice
(INHIBITOR)
Can nifedipine be used to treat dysrhythmias? - ANSWERS-No
Reflex tachycardia can occur with which CCB? - ANSWERS-Nifedipine
CYP450 inhibitors drug names - ANSWERS-Valproate, isoniazid, sulfonamides,
amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact pharmacodynamics and
pharmacokinetic properties of drugs? - ANSWERS-increase glomerular filtration rate
leads to increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic - ANSWERS-Antiepileptic drugs,
antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in large doses,
some anticoagulants, and hormonal medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in neonates? - ANSWERS-
slow and erratic due to low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased in infancy? - ANSWERS-
delayed gastric emptying
Some medications that should be avoided in the pediatric patient? - ANSWERS-
glucocorticoids, discoloration of developing teeth with tetracyclines, and kernicterus with
sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration patient education? - ANSWERS-
dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
, What are some things that put the elderly patient at higher risk for adverse drug
reactions? - ANSWERS-reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
How can healthcare providers decrease likelihood of an elderly patient experiencing an
adverse drug reaction? - ANSWERS-obtaining a thorough drug history that includes
over-the-counter medications
considering pharmacokinetic and pharmacodynamics changes due to age
monitoring the patient's clinical response and plasma drug levels
using the simplest regimen possible
monitoring for drug-drug interactions and iatrogenic illness
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the Beers list
How can we promote medication adherence with elderly patients? - ANSWERS-
simplifying drug regimens
providing clear and concise verbal and written instructions
using an appropriate dosage form
clearly labeling and dispensing easy-to-open containers
developing daily reminders
monitoring frequently
affordability of drugs
support systems
Why do nitrates need to be taken no later than 4 PM? - ANSWERS-Need nitrate free
interval so tolerance doesn't develop
Nine factors that impact outcome of medication? - ANSWERS-Gender and race
Genetics and pharmacogenomics
Variability in absorption
placebo effect
Tolerance
patho
age
bodyweight
Do you need informed consent for genetic testing? - ANSWERS-yes
