Please write clearly in block capitals.
Centre number Candidate number
Surname
Forename(s)
Candidate signature
I declare this is my own work.
GCSE
COMBINED SCIENCE: TRILOGY
Foundation Tier
F
Biology Paper 2F
Monday 9 June 2025 Morning Time allowed: 1 hour 15 minutes
Materials For Examiner’s Use
For this paper you must have:
a ruler Question Mark
a scientific calculator. 1
2
Instructions
3
Use black ink or black ball-point pen.
Pencil should only be used for drawing. 4
Fill in the boxes at the top of this page. 5
Answer all questions in the spaces provided. 6
If you need extra space for your answer(s), use the lined pages at
the end of this book. Write the question number against your TOTAL
answer(s).
Do all rough work in this book. Cross through any work you do not
want to be marked.
In all calculations, show clearly how you work out your answer.
Information
The maximum mark for this paper is 70.
The marks for questions are shown in brackets.
You are expected to use a calculator where appropriate.
You are reminded of the need for good English and clear presentation in your answers.
IB/M/Jun25/G4006/E9
8464/B/2F
, 2
Do not write
outside the
0 1 The concentration of glucose in the blood can be box
controlled.
0 1 .1 A person drinks a glucose solution.
What happens to the person’s blood glucose concentration soon after
drinking the glucose solution?
[1 mark]
Tick () one box.
Blood glucose concentration
decreases.
Blood glucose concentration stays the same.
Blood glucose concentration increases.
0 1 . Insulin controls blood glucose
2 concentration. Which organ produces
[1 mark]
insulin?
Tick () one box.
Pancreas
Pituitary
Stomach
IB/M/Jun25/8464/B/
2F
, 3
Do not write
outside the
0 1 . Organs affected by insulin are called target box
3 organs. Which two organs are target organs
[2 marks]
for insulin?
Tick () two boxes.
Liver
Lung
Muscle
Ovary
Spinal cord
0 1 .4 Complete the sentences.
Choose answers from the
[2 marks]
box.
DNA glucose glycogen urea
Insulin causes cells to take in .
The storage molecule made inside the cells is .
Question 1 continues on the next page
IB/M/Jun25/8464/B/
2F
, 4
Do not write
outside the
Turn over ►
IB/M/Jun25/8464/B/
2F
Centre number Candidate number
Surname
Forename(s)
Candidate signature
I declare this is my own work.
GCSE
COMBINED SCIENCE: TRILOGY
Foundation Tier
F
Biology Paper 2F
Monday 9 June 2025 Morning Time allowed: 1 hour 15 minutes
Materials For Examiner’s Use
For this paper you must have:
a ruler Question Mark
a scientific calculator. 1
2
Instructions
3
Use black ink or black ball-point pen.
Pencil should only be used for drawing. 4
Fill in the boxes at the top of this page. 5
Answer all questions in the spaces provided. 6
If you need extra space for your answer(s), use the lined pages at
the end of this book. Write the question number against your TOTAL
answer(s).
Do all rough work in this book. Cross through any work you do not
want to be marked.
In all calculations, show clearly how you work out your answer.
Information
The maximum mark for this paper is 70.
The marks for questions are shown in brackets.
You are expected to use a calculator where appropriate.
You are reminded of the need for good English and clear presentation in your answers.
IB/M/Jun25/G4006/E9
8464/B/2F
, 2
Do not write
outside the
0 1 The concentration of glucose in the blood can be box
controlled.
0 1 .1 A person drinks a glucose solution.
What happens to the person’s blood glucose concentration soon after
drinking the glucose solution?
[1 mark]
Tick () one box.
Blood glucose concentration
decreases.
Blood glucose concentration stays the same.
Blood glucose concentration increases.
0 1 . Insulin controls blood glucose
2 concentration. Which organ produces
[1 mark]
insulin?
Tick () one box.
Pancreas
Pituitary
Stomach
IB/M/Jun25/8464/B/
2F
, 3
Do not write
outside the
0 1 . Organs affected by insulin are called target box
3 organs. Which two organs are target organs
[2 marks]
for insulin?
Tick () two boxes.
Liver
Lung
Muscle
Ovary
Spinal cord
0 1 .4 Complete the sentences.
Choose answers from the
[2 marks]
box.
DNA glucose glycogen urea
Insulin causes cells to take in .
The storage molecule made inside the cells is .
Question 1 continues on the next page
IB/M/Jun25/8464/B/
2F
, 4
Do not write
outside the
Turn over ►
IB/M/Jun25/8464/B/
2F
