MARYVILLE UNIVERSITY PHARMACOLOGY EXAM
3 | PREMIUM STUDY GUIDES FOR EVERY STUDENT!
Procainamide is used to treat what? - Answer: It is an anti-arrhythmic and treats 1a arrhythmias.
Used for SVT and ventricular arrhythmias.
What is the dosing schedule for procainamide? - Answer: It has a short half life and needs to be
dosed every 3-4 hours.
What happens after 6 months of treatment with procainamide? - Answer: Procainamide anti-
nuclear antibodies are formed. Also, there is a high risk of toxicity.
Side effects of procainamide include? - Answer: Systemic lupus and symptoms related to lupus
What is the first line therapy for a patient with heart failure? - Answer: Angiotensin II
converting enzyme inhibitor (ACE inhibitor), or an ARB. Beta blockers
What population of people should not receive ACE or ARB? - Answer: African American
What would be a good alternative to ACE for African American populations? - Answer:
Hydralazine and Isosorbide nitrate
What is the recommended treatment for patients who had a markedly reduced EF? - Answer:
You should add an aldosterone antagonist (diuretic) to the ACE and Beta Blockers.
2nd line drug therapy for HF? - Answer: Digitalis but it has a narrow therapeutic window and
high degree of toxicity and does not show a mortality benefit.
What are the contraindications for Coumadin? - Answer: It is contraindicated for pregnancy and
with vitamin K.
What is the action of Coumadin? - Answer: It decreases the coagulation by inhibiting recycled
oxidized vitamin K. It does not antagonize Vitamin K, it just antagonizes the process of vitamin
K recycling which depletes active vitamin K.
pg. 1 ELIWAN EXAMINERS – YOUR SHORTCUT TO EXAM SUCCESS.
, What is the duration of a single dose of coumadin? - Answer: 2-5 days
What foods should people avoid eating while on Coumadin? - Answer: Green leafy vegetables
like kale and spinach
What is nitroglycerin used for? - Answer: Angina, AMI, Severe hypertension, coronary artery
spasms
Nitrates can cause what symptoms? - Answer: Severe headache, severe hypotension, certain
cases can cause bradycardia. This can affect compliance.
What is nitrate tolerance? - Answer: Loss of one or several of the effects of organic nitrates after
long-term use of nitrates.
What is the dosing schedule of nitrates? - Answer: Frequent dosing such as 3-4 times a day
How do you avoid tolerance to long-term nitrate? - Answer: Provide a 10-12 hour nitratd-free
interval when possible, so say the patient will take it at 0800, 1400, and then not the rest of the
day
If patients have breakthrough angina during that 12 hour free of long-acting nitrates what can
you suggest? - Answer: Using a short term nitrate like sublingual nitroglycerin during that time
Why should a thyroid panel be run on a patient while taking amiodorone? - Answer:
Amiodorone can cause the thyroid to not function properly. They thyroid can become either
hypo or hyper. TSH should be checked every 6 months.
What is a common side effect of Digoxin? - Answer: Patients can develop color vision
disturbances, mostly of yellow and green which is caleld tritanopia.
What are the most common indications for Digoxin? - Answer: A-fib, and A-flutter with RVR.
But this is not the first choice of med to use
pg. 2 ELIWAN EXAMINERS – YOUR SHORTCUT TO EXAM SUCCESS.
3 | PREMIUM STUDY GUIDES FOR EVERY STUDENT!
Procainamide is used to treat what? - Answer: It is an anti-arrhythmic and treats 1a arrhythmias.
Used for SVT and ventricular arrhythmias.
What is the dosing schedule for procainamide? - Answer: It has a short half life and needs to be
dosed every 3-4 hours.
What happens after 6 months of treatment with procainamide? - Answer: Procainamide anti-
nuclear antibodies are formed. Also, there is a high risk of toxicity.
Side effects of procainamide include? - Answer: Systemic lupus and symptoms related to lupus
What is the first line therapy for a patient with heart failure? - Answer: Angiotensin II
converting enzyme inhibitor (ACE inhibitor), or an ARB. Beta blockers
What population of people should not receive ACE or ARB? - Answer: African American
What would be a good alternative to ACE for African American populations? - Answer:
Hydralazine and Isosorbide nitrate
What is the recommended treatment for patients who had a markedly reduced EF? - Answer:
You should add an aldosterone antagonist (diuretic) to the ACE and Beta Blockers.
2nd line drug therapy for HF? - Answer: Digitalis but it has a narrow therapeutic window and
high degree of toxicity and does not show a mortality benefit.
What are the contraindications for Coumadin? - Answer: It is contraindicated for pregnancy and
with vitamin K.
What is the action of Coumadin? - Answer: It decreases the coagulation by inhibiting recycled
oxidized vitamin K. It does not antagonize Vitamin K, it just antagonizes the process of vitamin
K recycling which depletes active vitamin K.
pg. 1 ELIWAN EXAMINERS – YOUR SHORTCUT TO EXAM SUCCESS.
, What is the duration of a single dose of coumadin? - Answer: 2-5 days
What foods should people avoid eating while on Coumadin? - Answer: Green leafy vegetables
like kale and spinach
What is nitroglycerin used for? - Answer: Angina, AMI, Severe hypertension, coronary artery
spasms
Nitrates can cause what symptoms? - Answer: Severe headache, severe hypotension, certain
cases can cause bradycardia. This can affect compliance.
What is nitrate tolerance? - Answer: Loss of one or several of the effects of organic nitrates after
long-term use of nitrates.
What is the dosing schedule of nitrates? - Answer: Frequent dosing such as 3-4 times a day
How do you avoid tolerance to long-term nitrate? - Answer: Provide a 10-12 hour nitratd-free
interval when possible, so say the patient will take it at 0800, 1400, and then not the rest of the
day
If patients have breakthrough angina during that 12 hour free of long-acting nitrates what can
you suggest? - Answer: Using a short term nitrate like sublingual nitroglycerin during that time
Why should a thyroid panel be run on a patient while taking amiodorone? - Answer:
Amiodorone can cause the thyroid to not function properly. They thyroid can become either
hypo or hyper. TSH should be checked every 6 months.
What is a common side effect of Digoxin? - Answer: Patients can develop color vision
disturbances, mostly of yellow and green which is caleld tritanopia.
What are the most common indications for Digoxin? - Answer: A-fib, and A-flutter with RVR.
But this is not the first choice of med to use
pg. 2 ELIWAN EXAMINERS – YOUR SHORTCUT TO EXAM SUCCESS.
