PHM 350 FINAL | ELIWAN EXAMINARS — MASTER
EVERY TOPIC!
Hair loss, GI tract, suppressed bone marrow, liver and kidney damage - Answer: Classic side
effects of drugs for cancer therapy
Uses of alkylating agents - Answer: Hodgkin's disease, lymphoma, leukemia, ovarian, breast,
testicular cancers, head, neck, lung cancers, neuroblastomas, and brain tumors.
Antimetabolites - Answer: Only work effectively in S phase of cell cycle. Substitutes for normal
substrates in DNA.
Methotrexate - Answer: Also used for Crohn's disease and ulcerative colitis
Uses of antimetabolites - Answer: Breast and colorectal cancers, osteosarcoma, leukemias,
Non-Hodgkin's lymphoma
Mitotic inhibitors - Answer: Target microtubules so they cannot separate DNA during
replication. Can cause neuropathy. Vinblastine, vincristine, and paclitaxel.
Steroid hormone agonist - Answer: Slows replication
Steroid hormone antagonist - Answer: Enhances replication
-tinib - Answer: Tyrosine kinase inhibitor
Monoclonal antibody - Answer: Drug meant to carry alpha radioisotope directly to cancerous
cells. Do not cause hair loss nor simply target quickly replicating cells.
-mab - Answer: Monoclonal antibody
pg. 1
, Uticaria - Answer: Skin rash
Bacteriostatic - Answer: Inhibits bacterial growth
Sulfonamides and trimethoprim - Answer: Competitively block bacterial intermediary
metabolism
Penicillins cephalosporins and vancomycin - Answer: Cell wall disruption, inhibition of cell wall
synthesis
Erythromycin and clindamycin - Answer: Bacteriostatic inhibition of protein synthesis
Tetracyclines and aminoglycosides - Answer: Bactericidal inhibition of protein synthesis
Quinolones - Answer: Inhibition of DNA/RNA synthesis
Sulfonamide and trimethoprim - Answer: Anti folate antibacterials. Bacterial need it to make
purines.
Gram positive - Answer: Type of bacteria sensitive to penicillins
Clavulanate and sulbactam - Answer: Additives for penicillins. Penicillinase inhibitors.
Cef- - Answer: Cephalosporins
-cycline - Answer: Tetracyclines
-mycin - Answer: Aminoglycosides
-oxacin - Answer: Quinolones
pg. 2
EVERY TOPIC!
Hair loss, GI tract, suppressed bone marrow, liver and kidney damage - Answer: Classic side
effects of drugs for cancer therapy
Uses of alkylating agents - Answer: Hodgkin's disease, lymphoma, leukemia, ovarian, breast,
testicular cancers, head, neck, lung cancers, neuroblastomas, and brain tumors.
Antimetabolites - Answer: Only work effectively in S phase of cell cycle. Substitutes for normal
substrates in DNA.
Methotrexate - Answer: Also used for Crohn's disease and ulcerative colitis
Uses of antimetabolites - Answer: Breast and colorectal cancers, osteosarcoma, leukemias,
Non-Hodgkin's lymphoma
Mitotic inhibitors - Answer: Target microtubules so they cannot separate DNA during
replication. Can cause neuropathy. Vinblastine, vincristine, and paclitaxel.
Steroid hormone agonist - Answer: Slows replication
Steroid hormone antagonist - Answer: Enhances replication
-tinib - Answer: Tyrosine kinase inhibitor
Monoclonal antibody - Answer: Drug meant to carry alpha radioisotope directly to cancerous
cells. Do not cause hair loss nor simply target quickly replicating cells.
-mab - Answer: Monoclonal antibody
pg. 1
, Uticaria - Answer: Skin rash
Bacteriostatic - Answer: Inhibits bacterial growth
Sulfonamides and trimethoprim - Answer: Competitively block bacterial intermediary
metabolism
Penicillins cephalosporins and vancomycin - Answer: Cell wall disruption, inhibition of cell wall
synthesis
Erythromycin and clindamycin - Answer: Bacteriostatic inhibition of protein synthesis
Tetracyclines and aminoglycosides - Answer: Bactericidal inhibition of protein synthesis
Quinolones - Answer: Inhibition of DNA/RNA synthesis
Sulfonamide and trimethoprim - Answer: Anti folate antibacterials. Bacterial need it to make
purines.
Gram positive - Answer: Type of bacteria sensitive to penicillins
Clavulanate and sulbactam - Answer: Additives for penicillins. Penicillinase inhibitors.
Cef- - Answer: Cephalosporins
-cycline - Answer: Tetracyclines
-mycin - Answer: Aminoglycosides
-oxacin - Answer: Quinolones
pg. 2
