PHM 350 EXAM 2 Questions and Correct
Answers/ Latest Update / Already Graded
As a non steroidal anti-inflammatory drug, aspirin:
A. Inhibits the actions of both cyclooxygenase and lipoxygenase
B. Increases phagocytic macrophage migration into tissue at sites of
inflammation
C. Is used to treat headache and fever
D. Is used as a prophylactic medication to prevent development of
arthritis
E. None of the above.
Ans: C. Is used to treat headache and fever
As a non steroidal anti-inflammatory drug, aspirin:
A. Increases the activity and effects of cyclooxygenase but not of
lipoxygenase
B. Decreases phagocytic macrophage migration into tissue at sites of
inflammation
C. Is used to treat headache and fever because it does not cause
irritation of the gastro-intestinal tract
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D. Is used to prevent osteoporosis
E. A and C, above.
Ans: B. Decreases phagocytic macrophage migration into
tissue at sites of inflammation
Glucocorticoids such as predisnone (DELTASONE):
A. Induce hyperglycemia
B. Are useful to treat Type II diabetes
C. Are used to treat conditions characterized by chronic inflammation
D. Treat Type I diabetes because these drugs induce release insulin
from the pancreas
E. A and C, above.
Ans: E. A and C, above.
Which of the following statements about anti-inflammatory drugs is
correct?
A. One of the more frequent adverse side effects of indomethacin
(INDOCIN) is metaboliC acidosis
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B. One of the more frequent adverse side effects of aspirin is bone
marrow suppression
C. One of the more frequent adverse side effects of prednisone
(DELTASONE) is
development of osteoporosis
D. One of the more frequent adverse side effects of low dose aspirin is
suppression of blood clotting processes
E. A and C, above.
Ans: C. One of the more frequent adverse side effects of
prednisone (DELTASONE) is
development of osteoporosis
Which of the following drugs causes hepatotoxicity in overdose?
A. Celecoxib (CELEBREX)
B. Prednisone (DELTASONE)
C. Acetaminophen (TYLENOL)
D. Ibuprofen (MOTRIN)
E. A and C, above.
Ans: C. Acetaminophen (TYLENOL)
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The advantage of using celecoxib (CELEBREX) for treatment of
arthritis pain (compared to use of aspirin) is that:
A. Celecoxib produces gastrointestinal irritation at a lower incidence
than aspirin does
B. Celecoxib is a lipoxygenase inhibitor and aspirin is not
C. Celecoxib inhibits COX-2 but not COX-1 but aspirin only inhibits
COX-1
D. Celecoxib increases blood flow to the inflamed joints
E. A and C, above.
Ans: A. Celecoxib produces gastrointestinal irritation at a lower
incidence than aspirin does
Indomethacin (INDOCIN) is used to treat:
A. Gout
B. Infertility
C. Rheumatoid arthritis
D. Congestive heart failure
E. A and C.
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