ADVANCED PATHOPHYSIOLOGY, 2025/2026
WITH CORRECT/ACCURATE ANSWERS
GRADE A
AT CHAMBERLAIN
ADVANCED PATHOPHYSIOLOGY
1. A patient with normal lungs should be able to exhale ____ of the forced vital capacity
(FVC) within the first second.
,a. 95%
b. 50%
c. 80%
d. 99%
Correct Answer: c. 80%
Rationale: A normal FEV1/FVC ratio is ~80%, indicating non-obstructed airflow.
2. Simple spirometry includes measurement of residual capacity.
a. True
b. False
Correct Answer: b. False
Rationale: Residual volume (RV) and total lung capacity (TLC) require body
plethysmography, not simple spirometry.
3. FVC and TLC are both reduced. Which condition is most likely?
a. Pneumonia
b. Chronic asthma
c. Emphysema
d. Pulmonary fibrosis
Correct Answer: d. Pulmonary fibrosis
Rationale: Restrictive lung diseases show decreased TLC and FVC.
4. A patient with chronic bronchitis is most likely to experience:
a. Decreased FEV1
b. Decreased TLC
c. Increased FEV1
d. Increased TLC
Correct Answer: a. Decreased FEV1
Rationale: Airway obstruction narrows bronchi, lowering FEV1.
, 5. Which of the following indicates obstructive lung disease?
a. Chronic asthma
b. Pneumonia
c. Pulmonary fibrosis
d. Pulmonary hypertension
Correct Answer: a. Chronic asthma
Rationale: Obstructive disease includes asthma, chronic bronchitis, emphysema.
6. Which primarily results in chronic obstructive lung disease?
a. FEV1/FVC ↑, TLC ↑
b. FEV1 ↓, TLC ↓
c. FEV1/FVC ↓, TLC ↓
d. FEV1 ↓, FEV1/FVC ↓ (Correct Answer)
Rationale: Obstruction: reduced FEV1 + reduced FEV1/FVC.
7. FVC and TLC reduced but FEV1/FVC normal. Interpretation?
a. Obstructive
b. Mixed
c. Restrictive
d. Normal
Correct Answer: c. Restrictive
Rationale: Restriction = low TLC + low FVC + normal ratio.
8. Chronic Bronchitis is characterized by:
a. Decreased TLC
b. Decreased FEV1
c. Increased compliance
d. Increased diffusing capacity
Correct Answer: b. Decreased FEV1
Rationale: Mucus hypersecretion obstructs airflow.