ADVANCED PHARMACOLOGY FINAL EXAM QUESTIONS AND ANSWERS 2025
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? -
(ANSWER)To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - (ANSWER)Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with? -
(ANSWER)Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - (ANSWER)Aldosterone
antagonist
Heparin exerts its therapeutic action by what? - (ANSWER)Upregulating the activity of one of the body's
natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an anaphylactic
reaction. - (ANSWER)Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - (ANSWER)Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
hypertension? - (ANSWER)Thiazide diuretics
What is the effect of cardiac glycosides? - (ANSWER)Digitalis glycosides have a negative chronotropic
effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
(ANSWER)Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-receptor sites? -
(ANSWER)Atenolol (Tenormin)
, ADVANCED PHARMACOLOGY FINAL EXAM QUESTIONS AND ANSWERS 2025
What type of action does nitrates have on the body? - (ANSWER)Reduction in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with known
coronary artery disease? - (ANSWER)100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - (ANSWER)Depressing phase 4 depolarization and
lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-
establish eumetabolic state in a patient with Graves' disease? - (ANSWER)Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency? -
(ANSWER)Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart failure? -
(ANSWER)Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? - (ANSWER)Methyldopa
(Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker? - (ANSWER)Prazosin
(Minipress)
What is an expected effect of the use of a beta-adrenergic blocker to control angina? -
(ANSWER)Reduced force of cardiac contraction.
What side effect should be monitored closely in the elderly when taking Metformin (Glucophage) for
type 2 diabetes? - (ANSWER)Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? - (ANSWER)Deactivate and detoxify
medications and other substances.
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? -
(ANSWER)To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - (ANSWER)Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with? -
(ANSWER)Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - (ANSWER)Aldosterone
antagonist
Heparin exerts its therapeutic action by what? - (ANSWER)Upregulating the activity of one of the body's
natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an anaphylactic
reaction. - (ANSWER)Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - (ANSWER)Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
hypertension? - (ANSWER)Thiazide diuretics
What is the effect of cardiac glycosides? - (ANSWER)Digitalis glycosides have a negative chronotropic
effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
(ANSWER)Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-receptor sites? -
(ANSWER)Atenolol (Tenormin)
, ADVANCED PHARMACOLOGY FINAL EXAM QUESTIONS AND ANSWERS 2025
What type of action does nitrates have on the body? - (ANSWER)Reduction in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with known
coronary artery disease? - (ANSWER)100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - (ANSWER)Depressing phase 4 depolarization and
lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-
establish eumetabolic state in a patient with Graves' disease? - (ANSWER)Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency? -
(ANSWER)Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart failure? -
(ANSWER)Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? - (ANSWER)Methyldopa
(Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker? - (ANSWER)Prazosin
(Minipress)
What is an expected effect of the use of a beta-adrenergic blocker to control angina? -
(ANSWER)Reduced force of cardiac contraction.
What side effect should be monitored closely in the elderly when taking Metformin (Glucophage) for
type 2 diabetes? - (ANSWER)Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? - (ANSWER)Deactivate and detoxify
medications and other substances.
