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USA NU578 EXAM 3 QUESTIONS AND CORRECT ANSWERS. VERIFIED 2025/2026.

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USA NU578 EXAM 3 QUESTIONS AND CORRECT ANSWERS. VERIFIED 2025/2026.

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2025/2026
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USA NU578 EXAM 3 QUESTIONS AND
CORRECT ANSWERS. VERIFIED
2025/2026.




What is the moa for diuretics? - ANS Affects Maintenance of ecf volume and composition



What is the Path that urine takes through the nephron - ANS Glomerulus Prox convol
tube Loop of Henle: Descrnding limb Ascending limb DCT Collecting duct



What is the site of action for osmotic diuretics like

Mannitol? - ANS Proximal convoluted tubule



What is the Site of action for Thiazide diuretics like

HCTZ? - ANS Early distal convoluted tubule



What is the (site of action for Potassium sparing diuretics like

Spironolactone? - ANS Late distal convoluted tubule and collecting duct (distal nephron)



What is the sote of action for Loop diuretics like

Furosemide? - ANS Loop of Henle
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.

, Loop diuretics cause drug toxicity due to increased Na+ excretion. - ANS Lithium excretion is
decreased with hyponatremia and causes lithium toxicity.



Nephron order of diuretic action - ANS Osmotics Loops

Thiazides K+ sparing



PCT (proximal convoluted tubule) - ANS High resorptive capacity. About 65% of filtered Na+
and Cl resorbed here. Urine is isotonic



Freely permeable to water - ANS Descending limb loop of Henle



Na/K exchange: Na+ reabsorbed, K+ excreted stimulated by - ANS Distal nephron: late
DCT/CD



Causes transient deafness - ANS Furosemide



Only diuretic class that is ototoxic - ANS Loop diuretics (pg451)



Digoxin is potentiated with hypokalemia and ventricular dysrhythmias are greatly increased.
These diuretics promote K+ loss. - ANS Loop diuretics

Thiazide diuretics



Preferred drugs for mobilizing edema associated with mild to moderate failure -
ANS Thiazides



Diuretic Must be given parenterally. Only osmotic avail in US - ANS Mannitol

2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.

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