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Hemispheres 3.0 Level II Stroke Pathophysiology questions well answered

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Hemispheres 3.0 Level II Stroke Pathophysiology questions well answered

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November 19, 2025
Number of pages
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Written in
2025/2026
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Hemispheres 3.0 Level II Stroke
Pathophysiology questions well
answered

Ischemic Stroke - correct answer ✔✔ 87% of all strokes

Episode of neurological dysfunction due to focal cerebral, spinal or retinal infarction



Causes of ischemic stroke - correct answer ✔✔ complete blockage or reduction in cerebral
blood flow



Hemorrhagic stroke - correct answer ✔✔ 13% of all strokes

Rapidly developing neurological dysfunction due to focal collection of blood within the brain,
ventricular system, or subarachnoid space that is not caused by trauma



Cause of hemorrhagic stroke - correct answer ✔✔ vessel rupture

(commonly caused by HTN or aneurysm burst)



Penumbra - correct answer ✔✔ Ischemic tissue surrounding the infarcted core

Reduced CBF due to blocked artery but has additional inflow from adjacent arteries

Salvageable with timely intervention

Can tolerate reduced CBF for 6-8 hrs with collateral flow



Hematological and metabolic factors affecting damage from stroke - correct answer ✔✔
hypercoagulable state, fever, hyper or hypoglycemia



Small vessel occlusions (SVO) - correct answer ✔✔ Lacunar

, occur in small diameter penetrating branches of cerebral arteries



Large vessel occlusions (LVO) - correct answer ✔✔ occur in large-diameter vessels within the
extracranial and intracranial circulation



Thrombotic Stroke - correct answer ✔✔ occurs when an obstructive blood clot (thrombus forms
within a vessel in the brain



Embolic stroke - correct answer ✔✔ occurs when a blood clot, fat fragment, bacteria or air
bubble (embolus) forms in another location (usually the heart) and then travels to and obstructs
an artery supplying brain tissue



Etiology of strokes - correct answer ✔✔ Cardioembolism

Larger-artery atherosclerosis (embolus/thrombus)

small vessel occlusion (lacunar stroke)

Other known cause

Undetermined (cyrptogenic)



atherosclerosis - correct answer ✔✔ inflammatory disease process resulting in development of
fatty plaque deposits that build up inside arteries



Large artery atherosclerosis (aorta or ICA) - correct answer ✔✔ Can result in reduced blood flow
to the brain and stroke by:

Embolus formation when plaque breaks off, enters circulation and blocks a cerebral artery

Thrombus formation around plaque less commonly

Narrowing or stenosis



thrombotic stroke presentation - correct answer ✔✔ develops over hours, days or longer

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