Immunology Exam 5 Questions and correct answers Latest Update

Immunology Exam 5 Questions and correct answers Latest Update What term BEST describes a selection process against those cells whose T-cell receptors bind too strongly to self-peptide/MHC combinations? Positive selection Negative selection Lineage commitment Hematopoietic commitment to the T-cell lineage None are correct. Negative selection Name that cell. I am a small, nonproliferating cell found within the thymic cortex and contain CD4 and CD8 on my cell surface. DN thymocyte DP thymocyte Thymocyte DN1 cell DN2 cell DP thymocyte Hematopoietic stem cells cultured in the presence of which receptor differentiate into T cells rather than B cells? CD4 Cd8 Notch B7-1 CD3 Notch At what stage of T-cell development is the pre-TCR expressed? DN DP SP Pro-T cell None are correct. DN Costimulatory signals, such as CD28 and ICOS, are required to achieve optimal T-cell activation (via exposure to antigen) and are considered part of which of the three steps essential to this process? Signal 1 Signal 2 Signal 3 Both signal 1 and signal 2. Both signal 2 and signal 3. Signal 2 Committed lymphocyte progenitors originate in the