CWS EXAM PREP UPDATED QUESTIONS
AND CORRECT ANSWERS.
Name the five types of Cell Adhesion Molecules? Which type enables cells to detect and
interact with components of the extracellular matrix? - ANS 1. Cadherins
2. Immunoglobulin Superfamily (IGSF)
3. Selectins
4. Integrins
5. Mucins
Integrins allow cells to interact with the surrounding environment or components of the ECM.
What are the layers of the epidermis from most superficial to most deep? - ANS Stratum
corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale (germinativa)
What are the layers of the dermis from most superficial to most deep? - ANS Papillary dermis
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,Reticular dermis
What is/are the primary cell type(s) of the stratum spinosum? - ANS Langerhan's cells
What is/are the primary cell type(s) of the stratum basale? - ANS Keratinocytes, Melanocytes,
Merkel cells
What is/are the primary cell type(s) of the stratum granulosum? - ANS Corneocytes
(terminally differentiated keratinocytes)
What is/are the primary cell type(s) of the stratum corneum? - ANS Dead keratinocytes
What is/are the primary cell type(s) of the dermis? - ANS Fibroblasts, Mast cells,
Macrophages, Lymphocytes
Tissue loss includes only the epidermis. - ANS Superficial
Tissue loss includes the epidermis and part of the dermis. - ANS Partial thickness
Tissue loss includes the epidermis and all of the dermis. - ANS Full thickness
Tissue loss includes subcutaneous tissues. - ANS Subdermal
When does hemostasis or coagulation occur during the stages of healing? - ANS Immediately
after tissue injury
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,When does inflammation occur during the stages of healing? - ANS 0-4 days
When does proliferation occur during the stages of healing? - ANS 4-21 days
How long can remodeling last? - ANS Up to 2 years
What are the key cells of hemostasis? - ANS Platelets
What are the key cells of inflammation? - ANS Neutrophils, Macrophages
What are the key cells of proliferation? - ANS Fibroblasts, Epithelial cells, Endothelial cells,
Macrophages
What are the key cells of remodeling? - ANS Fibroblasts
What produces PDGF? - ANS Platelets and macrophages
What stimulates fibroblasts? - ANS Platelet Derived Growth Factor
What is an integrin? - ANS A cell surface receptor that enables cells to interact with
components of the ECM
What secretes MMPs and TIMPs? - ANS Keratinocytes and fibroblasts
What regulates the activity of MMPs? - ANS TIMPs
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, Fibroblasts play a key role in the extracellular matrix deposition of which types of proteins? -
ANS Collagen
Elastin
Reticulin
Proteoglycans
Glycosaminoglycans
Myofibroblasts secrete which type of collagen? - ANS Type I
Which type of collagen is primarily found in uninjured tissue? - ANS Type I
Which type of collagen is primarily found in wounds in the proliferative phase of wound
healing? - ANS Type III
What is the transitional marker between the inflammatory and proliferative phases of healing? -
ANS Macrophage migration into the wound site
Which cells are the last to arrive during the proliferative phase? - ANS T lymphocytes
What are the three types of T lymphocytes and what are their functions? - ANS 1. Cytotoxic T
cells = directly target and kill any antigen-bearing cells
2. Helper T cells = activate macrophages and B lymphocytes
3. Suppressor T cells = down regulate inflammation and proliferation as the wound reaches
maturity
What is considered the "first line of defense" in wound healing? - ANS Neutrophils (PMN
leukocytes)
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
AND CORRECT ANSWERS.
Name the five types of Cell Adhesion Molecules? Which type enables cells to detect and
interact with components of the extracellular matrix? - ANS 1. Cadherins
2. Immunoglobulin Superfamily (IGSF)
3. Selectins
4. Integrins
5. Mucins
Integrins allow cells to interact with the surrounding environment or components of the ECM.
What are the layers of the epidermis from most superficial to most deep? - ANS Stratum
corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale (germinativa)
What are the layers of the dermis from most superficial to most deep? - ANS Papillary dermis
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,Reticular dermis
What is/are the primary cell type(s) of the stratum spinosum? - ANS Langerhan's cells
What is/are the primary cell type(s) of the stratum basale? - ANS Keratinocytes, Melanocytes,
Merkel cells
What is/are the primary cell type(s) of the stratum granulosum? - ANS Corneocytes
(terminally differentiated keratinocytes)
What is/are the primary cell type(s) of the stratum corneum? - ANS Dead keratinocytes
What is/are the primary cell type(s) of the dermis? - ANS Fibroblasts, Mast cells,
Macrophages, Lymphocytes
Tissue loss includes only the epidermis. - ANS Superficial
Tissue loss includes the epidermis and part of the dermis. - ANS Partial thickness
Tissue loss includes the epidermis and all of the dermis. - ANS Full thickness
Tissue loss includes subcutaneous tissues. - ANS Subdermal
When does hemostasis or coagulation occur during the stages of healing? - ANS Immediately
after tissue injury
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,When does inflammation occur during the stages of healing? - ANS 0-4 days
When does proliferation occur during the stages of healing? - ANS 4-21 days
How long can remodeling last? - ANS Up to 2 years
What are the key cells of hemostasis? - ANS Platelets
What are the key cells of inflammation? - ANS Neutrophils, Macrophages
What are the key cells of proliferation? - ANS Fibroblasts, Epithelial cells, Endothelial cells,
Macrophages
What are the key cells of remodeling? - ANS Fibroblasts
What produces PDGF? - ANS Platelets and macrophages
What stimulates fibroblasts? - ANS Platelet Derived Growth Factor
What is an integrin? - ANS A cell surface receptor that enables cells to interact with
components of the ECM
What secretes MMPs and TIMPs? - ANS Keratinocytes and fibroblasts
What regulates the activity of MMPs? - ANS TIMPs
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, Fibroblasts play a key role in the extracellular matrix deposition of which types of proteins? -
ANS Collagen
Elastin
Reticulin
Proteoglycans
Glycosaminoglycans
Myofibroblasts secrete which type of collagen? - ANS Type I
Which type of collagen is primarily found in uninjured tissue? - ANS Type I
Which type of collagen is primarily found in wounds in the proliferative phase of wound
healing? - ANS Type III
What is the transitional marker between the inflammatory and proliferative phases of healing? -
ANS Macrophage migration into the wound site
Which cells are the last to arrive during the proliferative phase? - ANS T lymphocytes
What are the three types of T lymphocytes and what are their functions? - ANS 1. Cytotoxic T
cells = directly target and kill any antigen-bearing cells
2. Helper T cells = activate macrophages and B lymphocytes
3. Suppressor T cells = down regulate inflammation and proliferation as the wound reaches
maturity
What is considered the "first line of defense" in wound healing? - ANS Neutrophils (PMN
leukocytes)
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
