GRADED A| NEW VERSION
What is nephrotic syndrome- SELECTED ANSWER 👀 A
condition of increased glomerular permeability that allows
larger molecules to pass through the membrane into the urine
and then be excreted.
What are key features of nephrotic syndrome- SELECTED
ANSWER 👀 -*Massive proteinuria*
-*Hypoalbuminemia*
-*Edema (facial and periorbital)*
-Lipiduria
-Hyperlipidemia
-Increased coagulation
-Reduced kidney function
In nephrotic syndrome, severe protein loss in the urine is
greater than what- SELECTED ANSWER 👀 3.5g in 24 hours
,What is nephrotic syndrome treated with- SELECTED ANSWER
👀 -immunosuppressant agents (if immunity based).
-ACE inhibitors (decreased protein loss in urine)
-statins (improve blood lipid levels).
-Heparin (used to treat vascular effects and improve kidney
function)
Describe the "risk" stage for AKI - SELECTED ANSWER 👀
creatinine x 1.5 of normal, and GFR reduced by 25%
Describe the "injury" stage for AKI - SELECTED ANSWER 👀
creatinine x2 & GFR reduced by 50%
Describe the "failure" stage for AKI - SELECTED ANSWER 👀
creatinine x3 normal, & GFR reduced by 75% (Cant fix)
Describe Prerenal AKI. Give examples. - SELECTED ANSWER 👀
Decreased perfusion to kidneys.
-NSAIDs
-Severe dehydration
, -Renal artery stenosis
-MI or HF resulting in low ejection fraction and low cardiac
output
-Blood/ fluid loss
Describe Intrarenal AKI. Give examples. - SELECTED ANSWER 👀
Tissue damage to the actual kidneys.
-Glomerulonephritis or inflammation of the glomeruli
-Sepsis
-Intrarenal bleeding
-Pyelonephritis
Describe Postrenal AKI. Give examples. - SELECTED ANSWER 👀
Obstruction that occurs after the kidney.
-Enlarged prostate (BPH)
-Bladder Cancer
-Kidney stones