PAPER 2026 PRACTICE TEST QUESTIONS
WITH SOLUTIONS
⩥ Diseases associated with a dysfunction of polymorphonuclear
neutrophils (PMNs) include all of the following with the exception of:
A. Chediak Higashi Syndrome
B. Chronic Granulomatous Dz
C. Gaucher's Dz
D. Myeloperoxidase Deficiency. Answer: C. Gaucher's disease
⩥ In which of the following cells are Auer rods most likely to be seen?
A. Myeloblast
B. Lymphoblast
C. Erythroblast
D. Megakaryocyte. Answer: A. Myeloblast
⩥ A 55-year-old white male had the following lab data:
RBC 3.7 X 1012/L
Serum iron 220 µg/dL (N: 60-80 µg/dL)
TIBC 300 µg/dL (N: 260-400 µg/dL)
,Hct 32%
Serum Ferritin 2,800 ng/mL (N: 10-200 ng/mL)
WBC 5.8 x 109/L
MCV 86 fL
MCH 26 pg
MCHC 32%
Prussian Blue stain of bone marrow aspirate indicates markedly elevated
iron stores.
These laboratory results are MOST consistent with which of the
following conditions?
A. Sideroblastic anemia
B. Anemia of chronic dz
C. Hemochromatosis
D. Megaloblastic anemia. Answer: C. Hemochromatosis
Characteristic findings are elevations in serum iron and ferritin. Positive
Prussian Blue stain of the bone marrow indicates elevated iron
(hemosiderin) stores.
⩥ All of the following are associated with Hgb C disease, EXCEPT?
A. Hgb C Crystals
B. Target Cells
, C. Lysine substituted for glutamic acid at the sixth position of the beta
chain
D. Fast mobility of Hgb C at pH 8.6. Answer: D. Fast mobility of Hgb C
at pH 8.6
Hemoglobin C has a high positive charge and therefore has slow
mobility on electrophoresis using alkaline gel. Hemoglobin C migrates
with hemoglobin A2 and hemoglobin E on cellulose acetate
electrophoresis at pH 8.6
⩥ When performing controls for the morning run in coagulation, the
normal control is within acceptable limits for both the PT and APTT, but
the abnormal control is out of range for both procedures. Which of the
following would be an appropriate action to take?
A. Document the out of range QC and continue with the morning run
while reporting out only those results that are in normal range
B. Continue with the morning run and report out only those results that
fall within normal range
C. Document QC, then repeat controls at the end of the morning run and
report if both controls are acceptable
D. Document QC, repeat the abnormal control, troubleshoot if
necessary; report patient results only when both controls are within
acceptable ranges. Answer: Document QC, repeat the abnormal control,
troubleshoot if necessary; report patient results only when both controls
are within acceptable ranges