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Fundamental Concepts in Anatomy & Physiology: Gross Anatomy, Development, and Body Organisation

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This document is a comprehensive set of study notes covering the foundational principles of human anatomy and physiology. It explains key biological functions—such as metabolism, responsiveness, growth, development, differentiation, and reproduction—and details major anatomical methods, organ systems, body regions, abdominal divisions, and the structure and function of the peritoneum. It also distinguishes retroperitoneal and intraperitoneal organs and outlines how the body is organised for clinical examination and anatomical study. should not be used as the sole source of revision. Students should always supplement this material with textbook readings, lecture content, diagrams, practice questions, and practical anatomical resources to ensure a complete understanding of the subject

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1. METABOLISM
Definition

Metabolism is the total sum of all chemical reactions occurring inside an organism’s cells
and internal environment.
It includes reactions that:

 Use energy
 Release energy
 Build molecules (anabolism)
 Break molecules down (catabolism)

Together, these reactions allow the organism to:

 Stay alive
 Maintain internal balance
 Grow and develop
 Respond to the environment
 Reproduce




1.1 Two Major Divisions of Metabolism
A. Catabolism (breaking down)

 Larger molecules → smaller molecules
 Releases energy
 Example: digestive enzymes breaking down food
o Proteins → amino acids
o Carbohydrates → glucose
o Lipids → fatty acids
 Energy released is used for:
o Movement
o Heat production
o Cellular reactions




. Anabolism (building up)

 Smaller molecules → larger molecules
 Requires energy
 Examples:
o Building muscle proteins
o Synthesising hormones
o Repairing tissues

, o Forming new cell membranes




1.2 Importance of Molecular Shape
The passage emphasises a key concept in anatomy & physiology:

“The shape of a molecule determines its function.”

 Enzyme shape → determines what reactions it can catalyse
 Receptor shape → determines what signals it detects
 Antibody shape → determines what pathogens it binds

Changes in shape = changes in function.




1.3 Example: Immune Cell Shape-Changing
Some white blood cells (e.g., phagocytes) can:

 Change their shape
 Extend pseudopods
 Surround and engulf bacteria

This shape-changing ability is powered by metabolic energy.




2. RESPONSIVENESS
Definition

Responsiveness is an organism’s ability to:

 Detect changes (stimuli)
 Process them
 Respond appropriately

This includes both external and internal changes.




2.1 Examples of Responsiveness
External stimuli

Connected book
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Kenneth Saladin Human Anatomy
Publisher: 2019 ISBN: 9781260566000 Edition: Unknown

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November 14, 2025
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2023/2024
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Liu joan
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