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A disorder of the inner ear that causes episodes of vertigo, hearing loss, tinnitus (ringing in the
ear), and a feeling of fullness or pressure in the ear.
Maniere's Disease
vertical acceleration, the feeling of rising and falling
The saccule macula detects?
horizontal acceleration. Acceleration or Deceleration
The utricle macula detects?
1. An odorant binds to a G-protein coupled receptor on an olfactory cilium.
2. The G protein¸ gustducin¸ activates adenylate
3. The intracellular levels of cAMP within the olfactory sensory neuron increase.
4. cAMP-gated ion channels in the olfactory sensory neuron open.
5. The olfactory sensory neuron depolarizes and action potentials are carried to the olfactory
nerve fibers where they synapse with the mitral cells.
6.Mitral cells relay the information to the brain via the olfactory tract.
Events of olfactory transduction in order
Sympathetic division and Parasympathetic division
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,ANS is subdivided into two divisions
Fight or Fligh
Sympathetic Nervous System
-Rest and Digest
-Feed and Breed
Parasympathetic Nervous System
IMPORTANT The pre-ganglionic fibers of the parasympathetic ANS are craniosacral, meaning
they arise from the cell bodies of the nuclei of the cranial nerves and sacral spinal cord
segments
IMPORTANT The pre-ganglionic fibers of the parasympathetic ANS are craniosacral, meaning
they arise from the cell bodies of the nuclei of the cranial nerves and sacral spinal cord
segments
IMPORTANT It might be helpful to generalize by saying that the parasympathetic division
originates at the top and bottom of the CNS, whereas the sympathetic division originates in the
middle regions.
IMPORTANT It might be helpful to generalize by saying that the parasympathetic division
originates at the top and bottom of the CNS, whereas the sympathetic division originates in the
middle regions.
Receptors that are coupled to ion channels and affect the neuron by causing those channels to
open
Inotropic Receptors
IMPORTANT The term "craniosacral" refers to the origin of the pre-ganglionic fibers of the
parasympathetic autonomic nervous system (ANS). In this context, "cranio" refers to the head
(cranial) and "sacral" refers to the lower part of the spine (sacral).
IMPORTANT The term "craniosacral" refers to the origin of the pre-ganglionic fibers of the
parasympathetic autonomic nervous system (ANS). In this context, "cranio" refers to the head
(cranial) and "sacral" refers to the lower part of the spine (sacral).
-Activate G proteins that trigger signaling cascades when a ligand binds
-Slow acting but long lasting
Metabotropic receptors (G-protein coupled receptors)
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, Salvation
Lacrimation
Urination
Digestion
The functions of the parasympathetic nervous system are often oversimplified with the acronym
SLUD
IMPORTANT The cell bodies of sympathetic pre-ganglionic neurons are located in the thoracic
and lumbar segments of the spinal cord
IMPORTANT The cell bodies of sympathetic pre-ganglionic neurons are located in the thoracic
and lumbar segments of the spinal cord
Acetylcholine
Norepinephrine
Epinephrine
In the ANS, the three major neurotransmitters
Cholinergic receptor
A receptor that is activated by acetylcholine is referred to as a
Nicotinic Acetylcholine (ACh) Receptor
If a cholinergic receptor is ionotropic
Muscarinic Acetylcholine Receptor
If a cholinergic receptor is metabotropic
Adrenergic Receptors
A receptor that is activated by epinephrine or norepinephrine is referred to as
IMPORTANT An agonist is a chemical that can bind to the same receptor as a particular
neurotransmitter and have the same effect
IMPORTANT An agonist is a chemical that can bind to the same receptor as a particular
neurotransmitter and have the same effect
small crystals in the fluid-filled vestibular sacs of the inner ear that, when shifted by gravity,
stimulate nerve cells that inform the brain of the position of the head
Otoliths
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