NSC 830 ADVANCED PHARM; DIABETES
QUESTIONS AND ANSWERS 2025
Narrow Specturm - ...ANSWER... ✔ ✔Treat limited #
of organisms, Less likely to disrupt normal flora,
organism identified.
Broad Specturm - ...ANSWER... ✔ ✔Treats multiple
organisms, more likely to disrupt normal flora, causative
agent unknown.
Why would you select abx? - ...ANSWER... ✔ ✔Is
antimicrobial therapy indicated, make a clinical
diagnosis, collection of specimens for a cx or lab test,
make microbial diagnosis, select drug.
Extended spectrum - ...ANSWER... ✔ ✔treats
multiple organisms, more likely to disrupt normal flora,
used when causative organism is unknown.
Gram positive - ...ANSWER... ✔ ✔Purple, thick layer
,2|Page
Example of gram positive - ...ANSWER... ✔ ✔Group
A beta-strep
Strep PNA
Gram negative - ...ANSWER... ✔ ✔Red or pink, thin
layer
Example of gram negative - ...ANSWER... ✔ ✔H.
influenza
N. Gonoccocus
Atypical Organism - ...ANSWER... ✔ ✔colorless, no
layer
Example of Atypical organism - ...ANSWER... ✔
✔Macrolides- erythromycins
True or False: Atypical bacteria are resistent to becta-
lactum abx - ...ANSWER... ✔ ✔True
,3|Page
Risk factors for Drug Resistant Strep PNA (DRSP) -
...ANSWER... ✔ ✔Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10
mg/day long term).
Treatment for Drug Resistant Strep PNA - ...ANSWER...
✔ ✔High dose amoxicillin 3-4g/day
Respiratory fluoroquinolones: moxifloxican,
gemifloxican, levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
Factors to determine when selecting an abx... -
...ANSWER... ✔ ✔Allergy history (PCN- risk of cross
allergy with cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
, 4|Page
What are 2 abx contraindicated in pregnancy? -
...ANSWER... ✔ ✔tetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or
baceriostiatic? - ...ANSWER... ✔ ✔Bactericidals
What are bactericidals? - ...ANSWER... ✔ ✔Kills
bacteria
What are bacteriostatic? - ...ANSWER... ✔
✔Restrains production of bacteria. The patient needs a
good immune system.
Minimum inhibitory concentration (MIC) - ...ANSWER...
✔ ✔Min. amount of abx used to inhibit growth of
bacteria. Abx usually dosed 2-4 times MIC
Teaching the patient to ..... - ...ANSWER... ✔ ✔Take
ALL of medication
May need back up birth control and for 7 days after.
Report signs of allergic reaction (SOA, Wheezing, rash)