By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton
Complete
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihn
wd wd wd wd wd wd wd wd
ganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
wd wd wd wd wd wd wd
MULTIPLEwdCHOICE
1. WhichwdnamewdidentifieswdawddrugwdlistedwdbywdthewdUSwdFoo
dwdandwdDrugwdAdministrationwd(FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS:wd C
Thewdofficialwdnamewdiswdthew d namewdunderwdwhichwdawddrugwdiswd
listedwdbywdthewdFDA.wdThewdbrandwdname,wdorwdtrademark,wdiswdt
hewdnamewdgivenwdtowdawddrugwdbywditswdmanufacturer.wdThewdnon
proprietary,wdorwdgeneric,wdnamewdiswdprovidedwdbywdthewdUnited
wdStateswdAdoptedwdNameswdCouncil.
DIF: CognitivewdLevel:wdKnowledge REF:w d p.wd9
OBJ:wd1NAT:wdNCLEXwdClientwdNeedswdCategory:wdSafe,wdEffective
wdCarewdEnvironmentwdTOP:w d NursingwdProcesswdStep:wdAssessment
CON:w
dPatientwdEducation
2. Whichwdsourcewdcontainswdinformationwdspecificwdtowdnutritionalwdsupplements?
a. USPwdDictionarywdofwdUSANwd &wdInternationalwdDrugwdNames
b. NaturalwdMedicineswdComprehensivewdDatabase
c. UnitedwdStateswdPharmacopoeia/NationalwdFormularywd(USPwdNF)
d. DrugwdInteractionwdFacts
ANS:wd C
UnitedwdStateswdPharmacopoeia/NationalwdFormularywdcontainswdinformationwdspecificwdtowdnutriti
onalwdsupplements.wdUSPwdDictionarywdofwdUSANwd&wdInternationalwdDrugwdNameswdiswdawdcompila
tionwdofwddrugwdnames,wdpronunciationwdguide,wdandwdpossiblewdfuturewdFDAwdapprovedwddrugs;wditwd
doeswdnotwdincludewdnutritionalwdsupplements.wdNaturalwdMedicineswdComprehensivewdDatabasewd
contains
evidence-
basedwdinformationwdonwdherbalwdmedicineswdandwdherbalwdcombinationwdproducts;wditwddoeswdnotwdinc
ludewdinformationwdspecificwdtowdnutritionalwdsupplements.wdDrugwdInteractionwdFactswdcontainswdc
omprehensivewdinformationwdonwddrugwdinteractionwdfacts;wditwddoeswdnotwdincludewdnutritionalwdsup
plements.
DIF: CognitivewdLevel:wdKnowledge REF:w d p.wd4
OBJ:wd3wdNAT:w d NCLEXwdClientwdNeedswdCategory:wdPhysiologica
lwdIntegrity
TOP:w d NursingwdProcesswdStep:wdAssessment CON:w d Nutritionwd|wdPatientwdEducation
3. Whichwddrugwdreferencewdcontainswddrugwdmonographswdthatwddescribewdallwddrugswdinwdawdtherapeuticwdclass?
a. DrugwdFactswdandwdComparisons
,TestwdBankwdForwdClayton’swdBasicwdPharmacologywdforwdNurseswd19thwdE 3
dition
b. DrugwdInteractionwdFacts
c. HandbookwdonwdInjectablewdDrugs
d. Martindale—ThewdCompletewdDrugwdReference
ANS:wd A
DrugwdFactswdandwdComparisonswdcontainswddrugwdmonographswdthatwddescribewdallwddrugs
wdinwdawdtherapeuticwdclass.wdMonographs wdarewdformattedwdaswdtableswdtowdallowwdcomparison
wdofwdsimilarwdproducts,wdbrandwdnames,wdmanufacturers,wdcost wdindices,wdandwdavailablewdd
osagewdformswdOnlinewdversionwdiswdavailable.
DIF: CognitivewdLevel:wdKnowledge REF:w d p.wd4wdTablewd1.2
OBJ:w d w d 3 NAT:w d NCLEXwdClientwdNeedswdCategory:wdPhysiologicalwdIntegrity
TOP:w d NursingwdProcesswdStep:wdAssessment CON:w d Safetywd|wdPatientwdEducationwd|wdClinicalwdJudgment
4. Whichwddrugwdreferencewdcontainswdmonographswdaboutwdvirtuallywdeverywdsingle-
entitywddrugwdavailablewdinwdthewdUnitedwdStateswdandwddescribeswdtherapeuticwduseswdofwddrugs,wdin
cludingwdapprovedwdandwdunapprovedwduses?
a. Martindale:wdThewdCompletewdDrugwdReference
b. AHFSwdDrugwdInformation
c. DrugwdReference
d. DrugwdFactswdandwdComparisons
ANS:wd B
AHFSwdDrugwdInformationwdcontainswdmonographswdaboutwdvirtuallywdeverywdsingle-
entitywddrugwdavailablewdinwdthewdUnitedwdStateswdandwddescribeswdtherapeuticwduseswdofwddrugs,wdinclu
dingwdapprovedwdandwdunapprovedwduses.
DIF: CognitivewdLevel:wdKnowledge REF:w d p.wd4wdTablewd1.2
OBJ:w d w d 3 NAT:w d NCLEXwdClientwdNeedswdCategory:wdPhysiologicalwdIntegrity
TOP:w d NursingwdProcesswdStep:wdPlanning CON:w d Safetywd|wdPatientwdEducationwd|wdClinicalwdJudgment
5. Whichwdonlinewddrugwdreferencewdmakeswdavailablewdtowdhealthcarewdproviderswdandwdthewdpubli
cwdawdstandard,wdcomprehensive,wdup-to-
datewdlookwdupwdandwddownloadablewdresourcewdaboutwdmedicines?
a. AmericanwdDrugwdIndex
b. AmericanwdHospitalwdFormulary
c. DailyMed
d. DrugwdReference
ANS:wd C
DailyMedwdmakeswdavailablewdtowdhealthcarewdproviderswdandwdthewdpublicwdawdstandard,wdcompreh
ensive,wdup-to-
datewdlookwdupwdandwddownloadablewdresourcewdaboutwdmedicines.wdThewdAmericanwdDrugwdIndexwdis
wdnotwdappropriatewdforwdpatientwduse.wdThewdAmericanwdHospital wdFormularywdiswdnot wdappropriate
wdforwdpatient wduse.wdThewddrugwdreferencewdiswdnotwdappropriatewdforwdpatient wduse.
DIF: CognitivewdLevel:wdKnowledge REF:w d p.wd3wd|wdp.wd4
OBJ:wd3wdNAT:w d NCLEXwdClientwdNeedswdCategory:wdPhysiologica
lwdIntegrity
TOP:wd NursingwdProcesswdStep:wdImplementation
CON:w d Safetywd|wdPatientwdEducationwd|wdClinicalwdJudgment
6. WhichwdlegislationwdauthorizeswdthewdFDAwdtowddeterminewdthewdsafetywdofwdawddrugwdbeforewditswdmarketing?
a. FederalwdFood,wdDrug,wdandwdCosmeticwdActwd(1938)
b. DurhamwdHumphreywdAmendmentwd(1952)
, TestwdBankwdForwdClayton’swdBasicwdPharmacologywdforwdNurseswd19thwdE 4
dition
c. ControlledwdSubstanceswdActwd(1970)
d. KefauverwdHarriswdDrugwdAmendmentwd(1962)
ANS:wd A
ThewdFederalwdFood,wdDrug,wdandwdCosmeticwdActwdofwd1938wdauthorizedwdthewdFDAwdtowddetermine
wdthewdsafetywdofwdallwddrugswdbeforewdmarketing. wdLaterwdamendments wdandwdacts wdhelpedwdtightenwd
FDAwdcontrolwdandwdensurewddrugwdsafety.wdThewdDurhamwdHumphreywdAmendmentwddefineswdthew
dkindswdofwddrugs wdthatwdcannotwdbewdusedwdsafelywdwithoutwdmedical wdsupervisionwdandwdrestrictswdth
eirwdsalewdtowdprescriptionwdbywdawdlicensedwdpractitioner.wdThewdControlledwdSubstanceswdActwdaddre
sseswdonlywdcontrolledwdsubstanceswdandwdtheirwdcategorization.wdThewdKefauverwdHarriswdDrugwdAm
endmentwdensureswddrugwdefficacywdandwdgreaterwddrugwdsafety.wdDrugwdmanufacturerswdarewdrequire
dwdtowdprovewdtowdthewdFDAwdthewdeffectivenesswdofwdtheirwdproductswdbeforewdmarketingwdthem.
DIF: CognitivewdLevel:wdKnowledge REF:w d p.wd5wdTablewdl.3
OBJ:w d 5
NAT:wdNCLEXwdClientwdNeedswdCategory:wdPhysiologicalwdInte
gritywdTOP:w d NursingwdProcesswdStep:wdAssessment
CON:w d Safetywd|wdPatientwdEducationwd|wdEvidencewd|wdHealthwdCarewdLaw
7. Whichwdclassificationwddoeswdmeperidinewd(Demerol)wdfallwdunder?
a. I
b. II
c. III
d. IV
ANS:wd B
Meperidinewd(Demerol)wdiswdawdSchedulewdIIwddrug;wditwdhaswdawdhighwdpotentialwdforwdabusewdandwdma
ywdleadwdtowdseverewdpsychologicalwdandwdphysicalwddependence.wdSchedulewdIwddrugswdhavewdhighwdpo
tentialwdforwdabusewdandwdnowdrecognizedwdmedicalwduse.wdSchedulewdIIIwddrugswdhavewdsomewdpotent
ialwdforwdabuse.wdUsewdmaywdleadwdtowdlowwdtowdmoderatewdphysicalwddependencewdorwdhighwdpsychol
ogicalwddependence.wdSchedulewdIVwddrugswdhavewdlowwdpotentialwdforwdabuse.wdUsewdmaywdleadwdtow
dlimitedwdphysicalwdorwdpsychological wddependence.
DIF: CognitivewdLevel:wdKnowledge REF:w d p.wd10
OBJ:wd2wdNAT:w d NCLEXwdClientwdNeedswdCategory:wdSafe,wdEffecti
vewdCarewdEnvironment
TOP:w d NursingwdProcesswdStep:wdAssessment CON:w d PatientwdEducationwd|wdAddictionwd|wdPain
8. WhichwdactionwdwouldwdthewdFDAwdtakewdtowdexpeditewddrugwddevelopmentwdandwdapprovalwdforwdanwdo
utbreakwdofwdsmallpox?
a. Listwdsmallpoxwdaswdawdhealthwdorphanwddisease.
b. Omitwdthewdpreclinicalwdresearchwdphase.
c. Extendwdthewdclinicalwdresearchwdphase.
d. Fastwdtrackwdthewdinvestigationalwddrug.
ANS:wd D
OncewdthewdInvestigationalwdNewwdDrugwdApplicationwdhaswdbeenwdapproved,wdthewddrugwdcanwdrece
ivewdhighestwdprioritywdwithinwdthewdagency,wdwhichwdiswdcalledwdfastwdtracking.wdAwdsmallpoxwdoutb
reakwdwouldwdbecomewdawdprioritywdconcernwdinwdthewdworld.wdOrphanwddiseaseswdarewdnotwdresearch
edwdinwdawdprioritywdmanner.wdPreclinicalwdresearchwdiswdnotwdomitted.wdExtendingwdanywdphasewdofwdt
hewdresearchwdwouldwdmeanwdawdlongerwdtimewdtowddevelopwdawdvaccine.wdThewdFDAwdmustwdensurewdth
atwdallwdphaseswdofwdthewdpreclinicalwdandwdclinicalwdresearchwdphasewdhavewdbeenwdcompletedwdinwdawd
safewdmanner.
DIF: CognitivewdLevel:wdKnowledge REF:w d w d p.wd7 OBJ:wd 5