Solutions
3 stages of transcription Correct Answers 1. initiation
2. elongation
3. termination
4 fold degeneracy Correct Answers 4 codons will code for the
same amino acid
5' capping Correct Answers what is it: modified 7-
methylguanosine cap nucleotide added to the 5' end
enzyme doesn't recognize this
what it does:
1. regulate nuclear export
2. prevent degradation by exonucleases in cytoplasm
3. promote translation
4. promote 5' proximal intron removal
a strand of dna Correct Answers a polymer of nucleotides
nucleotides linked together by phosphodiester bonds
the 5' phosphate of one nucleotide undergoes a dehydration
reaction with the 3' hydroxyl of the next nucleotide (dehydration
synthesis makes phosphodiester bonds)
after pre mra processing Correct Answers the mature eukaryotic
mra is ready to export
aging Correct Answers number of cell division is limited
telomerase activity stops
,protection against cancer: telomerase stops uncontrolled cell
division
anticodon (nucleotide triplet) Correct Answers recognizes a
complementary codon on the mrna
used to read mrna codon
H bonds to it
"decoder"
assembly of other transcription factors Correct Answers may
also be required, especially in eukaryotes
bacteria assembles around the AUG Correct Answers
eukaryotes use the 5' cap and poly-a tail for assembly then scan
for the start sight
bacterial initiation Correct Answers triplet H bond with
ribosomal bonding sequence initiation brings together the
translation complex (small ribosomal subunit, large ribosomal
subunit, mrna and initiatior trna)
establishes the correct reading frame
requires other initiation factors and energy in the form of GTP
hydrolysis
benign tumor Correct Answers grows slowly, not a problem
bonds between amino acids in polymer Correct Answers
peptide bonds
brca1 mutation Correct Answers dna can't be repaired and cell
cycle doesn't stop
, cancer Correct Answers a disease characterized by uncontrolled
cell division with the potential to spread to the rest of the body
caused by genetic changes
carbon #3 Correct Answers defines the 3' end of a template
strand
carbon #5 Correct Answers defines the 5' end of a template
strand
central dogma Correct Answers dna -> pre mrna -> mrna ->
protein
changes in dna sequence Correct Answers will change the mrna
sequence which can change the amino acid sequence and that
can change protein function
chargaff's rules Correct Answers in any species there are an
equal number of a and t bases and an equal amount of g and c
bases
check points Correct Answers very important for regulating the
cell cycle and for preventing cancer
coding sequence Correct Answers has the code for your protein
coding strand Correct Answers the non template strand
codon Correct Answers every 3 nucleotides
1 codon = 1 amino acid