APEA- Psych Pharm Questions with
Correct Answers
Bupropion (Wellbutrin), used in the treatment of depression, should NOT be
administered to a patient with:
alcoholism.
attention deficit disorder.
hypertension.
seizure disorder. - ANSWERSseizure disorder.
First-generation antipsychotics (e.g., haloperidol [Haldol]) are associated with side
effects including:
sedation.
tardive dyskinesia.
weight gain.
weight loss. - ANSWERStardive dyskinesia.
If methylphenidate is contraindicated, which of the following medications is
recommended for treatment of ADHD in an adult?
Bupropion (Wellbutrin)
Clonazepam (Klonopin)
Fluoxetine (Prozac)
Phenelzine (Nardil) - ANSWERSBupropion (Wellbutrin)
Therapeutic drug levels and predictability of clinical response are difficult to determine in
first-generation antipsychotics (e.g., haloperidol [Haldol]) because they:
are poorly absorbed in the intestines, hydrophilic and highly protein bound.
are highly bioavailable and poorly protein bound.
have a decreased first pass effect, are hydrophilic and poorly protein bound.
have variable bioavailability, are lipophilic and highly protein bound. - ANSWERShave
variable bioavailability, are lipophilic and highly protein bound.
Guanfacine (Intuniv), used in the treatment of attention deficit disorder, is classified as
a(n):
alpha-2-adrenergic agonist.
selective norepinephrine reuptake inhibitor.
sympathomimetic/stimulant.
tricyclic antidepressant. - ANSWERSalpha-2-adrenergic agonist.
Suvorexant (Belsomra), used in the treatment of insomnia, induces sleep by:
activating melatonin receptors.
blocking the signals of orexin chemicals in the hypothalamus.
increasing the catabolism of tryptophan.
, raising the levels of gamma-aminobutyric acid (GABA). - ANSWERSblocking the signals
of orexin chemicals in the hypothalamus.
The mechanism of action of second-generation antipsychotic medications such as
aripiprazole (Abilify) does NOT include:
5-HT2A receptor blockade.
dopamine D2 receptor blockade.
serotonin reuptake stimulation.
enhanced dopamine release. - ANSWERSserotonin reuptake stimulation.
After initiation or increase in dose of a selective serotonin receptor inhibitor (SSRI) such
as escitalopram (Lexapro), the patient should be monitored for:
agitation, hypersalivation and decreased bowel sounds.
hypothermia, dilated pupils and diaphoresis.
hyperthermia, akathisia and clonus.
lead pipe rigidity, hyporeflexia and tachypnea. - ANSWERShyperthermia, akathisia and
clonus.
Which statement about naltrexone (Vivitrol) is correct?
The patient may develop tolerance to naltrexone.
Naltrexone should be tapered once desired results are achieved.
The patient should be aware that a possible "rebound" effect may occur after
discontinuation.
Naltrexone does not cause physical dependence. - ANSWERSNaltrexone does not
cause physical dependence.
The generic name for Intuniv, used in the treatment of attention deficit disorder, is:
atomoxetine.
guaifenesin.
guanfacine.
dextroamphetamine. - ANSWERSguanfacine.
A side effect NOT associated with the use of suvorexant (Belsomra) is:
amnesia.
cataplexy.
sleep paralysis.
hypogonadism. - ANSWERShypogonadism.
Ramelteon (Rozerem), a melatonin receptor agonist:
is not likely to cause sleep walking or sleep driving.
is safe for patients with sleep apnea.
does not affect testosterone or prolactin levels.
should be used with caution in patients with liver disease. - ANSWERSshould be used
with caution in patients with liver disease.
Fluvoxamine (Luvox) is approved for the treatment of:
Correct Answers
Bupropion (Wellbutrin), used in the treatment of depression, should NOT be
administered to a patient with:
alcoholism.
attention deficit disorder.
hypertension.
seizure disorder. - ANSWERSseizure disorder.
First-generation antipsychotics (e.g., haloperidol [Haldol]) are associated with side
effects including:
sedation.
tardive dyskinesia.
weight gain.
weight loss. - ANSWERStardive dyskinesia.
If methylphenidate is contraindicated, which of the following medications is
recommended for treatment of ADHD in an adult?
Bupropion (Wellbutrin)
Clonazepam (Klonopin)
Fluoxetine (Prozac)
Phenelzine (Nardil) - ANSWERSBupropion (Wellbutrin)
Therapeutic drug levels and predictability of clinical response are difficult to determine in
first-generation antipsychotics (e.g., haloperidol [Haldol]) because they:
are poorly absorbed in the intestines, hydrophilic and highly protein bound.
are highly bioavailable and poorly protein bound.
have a decreased first pass effect, are hydrophilic and poorly protein bound.
have variable bioavailability, are lipophilic and highly protein bound. - ANSWERShave
variable bioavailability, are lipophilic and highly protein bound.
Guanfacine (Intuniv), used in the treatment of attention deficit disorder, is classified as
a(n):
alpha-2-adrenergic agonist.
selective norepinephrine reuptake inhibitor.
sympathomimetic/stimulant.
tricyclic antidepressant. - ANSWERSalpha-2-adrenergic agonist.
Suvorexant (Belsomra), used in the treatment of insomnia, induces sleep by:
activating melatonin receptors.
blocking the signals of orexin chemicals in the hypothalamus.
increasing the catabolism of tryptophan.
, raising the levels of gamma-aminobutyric acid (GABA). - ANSWERSblocking the signals
of orexin chemicals in the hypothalamus.
The mechanism of action of second-generation antipsychotic medications such as
aripiprazole (Abilify) does NOT include:
5-HT2A receptor blockade.
dopamine D2 receptor blockade.
serotonin reuptake stimulation.
enhanced dopamine release. - ANSWERSserotonin reuptake stimulation.
After initiation or increase in dose of a selective serotonin receptor inhibitor (SSRI) such
as escitalopram (Lexapro), the patient should be monitored for:
agitation, hypersalivation and decreased bowel sounds.
hypothermia, dilated pupils and diaphoresis.
hyperthermia, akathisia and clonus.
lead pipe rigidity, hyporeflexia and tachypnea. - ANSWERShyperthermia, akathisia and
clonus.
Which statement about naltrexone (Vivitrol) is correct?
The patient may develop tolerance to naltrexone.
Naltrexone should be tapered once desired results are achieved.
The patient should be aware that a possible "rebound" effect may occur after
discontinuation.
Naltrexone does not cause physical dependence. - ANSWERSNaltrexone does not
cause physical dependence.
The generic name for Intuniv, used in the treatment of attention deficit disorder, is:
atomoxetine.
guaifenesin.
guanfacine.
dextroamphetamine. - ANSWERSguanfacine.
A side effect NOT associated with the use of suvorexant (Belsomra) is:
amnesia.
cataplexy.
sleep paralysis.
hypogonadism. - ANSWERShypogonadism.
Ramelteon (Rozerem), a melatonin receptor agonist:
is not likely to cause sleep walking or sleep driving.
is safe for patients with sleep apnea.
does not affect testosterone or prolactin levels.
should be used with caution in patients with liver disease. - ANSWERSshould be used
with caution in patients with liver disease.
Fluvoxamine (Luvox) is approved for the treatment of:
