Update ) Advanced
Pharmacology for Care of the Family
| Questions & Answers | Grade A |
100% Correct – Chamberlain
Question:
What is the primary action of cholinesterase inhibitors in Alzheimer's
Disease?
Answer:
Prevent the breakdown of acetylcholine by acetylcholinesterase.
Question:
What are the potential gastrointestinal side effects of cholinesterase
inhibitors?
Answer:
Nausea, vomiting, diarrhea, and dyspepsia.
,Question:
What cardiovascular effect can cholinesterase inhibitors cause?
Answer:
Bradycardia, which can lead to fainting and falls.
Question:
What should be monitored in patients taking topiramate?
Answer:
Frequency and type of seizures, degree of CNS change, and signs of
depression or behavior change.
Question:
What is the main therapeutic goal of using drugs in seizure disorders?
Answer:
To suppress seizures that depend on high-frequency neuronal discharge.
Question:
What mutation should phenytoin not be prescribed for?
Answer:
HLA-B*1502 mutation, which occurs almost exclusively in people of Asian
descent.
,Question:
What are the teratogenic effects of phenytoin during pregnancy?
Answer:
Risks include cleft palate, heart malformations, and fetal hydantoin
syndrome, characterized by growth deficiency, motor or mental deficiency,
microcephaly, craniofacial distortion, positional deformities of the limbs,
hypoplasia of the nails and fingers, and impaired neurodevelopment.
Question:
What cardiovascular effects can occur with IV administration of phenytoin?
Answer:
Cardiac dysrhythmias and hypotension
Question:
What is the maximum recommended rate for IV phenytoin administration?
Answer:
Phenytoin should be injected no faster than 50 mg/min.
, Question:
What is the black box warning associated with phenytoin?
Answer:
Administering phenytoin faster than 50 mg/min via IV can cause severe
hypotension and cardiac dysrhythmias.
Question:
How does phenytoin affect oral contraceptives and warfarin?
Answer:
Phenytoin can decrease the effects of oral contraceptives and warfarin due to
its induction of hepatic enzymes.
Question:
What are the common adverse effects of gabapentin?
Answer:
Drowsiness, dizziness, fatigue, and ataxia.
Question:
What is the only form of gabapentin approved for epilepsy?
Answer:
Neurontin.