Final Exam: NR 566 / NR566 (Latest
Update ) Advanced
Pharmacology for Care of the Family
| Questions & Verified Answers |
100% Correct | Grade A -
Chamberlain
Question:
Levodopa and dietary factors
Answer:
Food can delay absorption by slowing gastric emptying especially high protein
foods
Question:
Levodopa MOA
Answer:
increases synthesis of dopamine in the brain
,Question:
How long does Levodopa take for therapeutic effect
Answer:
several months
Question:
Initial treatment selection for Parkinsons
Answer:
Mild symptoms> MAO-B inhibitor
Severe symptoms> Levodopa or a dopamine agonist> Pramipexole, Ropinirole
Question:
Adverse effects of carbidopa/levodopa
Answer:
Orthostatic hypotension
Neuropsychiatric disturbances
Confusion
Hallucinations
Delusions
Psychosis
,Question:
Ways to prevent side effects of carbidopa/levodopa
Answer:
DO not take with high protein foods
N/V can be reduced by taking with low-fat foods
Question:
Dopamine agonists prototype drugs
Answer:
Drug of choice for mild to moderate symptoms
pramipexole, ropinirole, rotigotine and apomorphine.
Question:
Tolcapone adverse effects
Answer:
Used only if safer drugs are ineffective
Intensifies levodopa related effects including dyskinesias, orthostatic
hypotension, hallucinations
, Question:
Black box warning for Tolcapone
Answer:
Live failure
Question:
Side effects of dopamine agonists
Answer:
N/V
Drowsiness
Dyskinesias (tics)
Ortho hypotension
Darkening of urine and sweat
Psychosis
Question:
Dopamine agonist MOA
Answer:
stimulate dopamine receptors in the brain without enzymatic conversion
Update ) Advanced
Pharmacology for Care of the Family
| Questions & Verified Answers |
100% Correct | Grade A -
Chamberlain
Question:
Levodopa and dietary factors
Answer:
Food can delay absorption by slowing gastric emptying especially high protein
foods
Question:
Levodopa MOA
Answer:
increases synthesis of dopamine in the brain
,Question:
How long does Levodopa take for therapeutic effect
Answer:
several months
Question:
Initial treatment selection for Parkinsons
Answer:
Mild symptoms> MAO-B inhibitor
Severe symptoms> Levodopa or a dopamine agonist> Pramipexole, Ropinirole
Question:
Adverse effects of carbidopa/levodopa
Answer:
Orthostatic hypotension
Neuropsychiatric disturbances
Confusion
Hallucinations
Delusions
Psychosis
,Question:
Ways to prevent side effects of carbidopa/levodopa
Answer:
DO not take with high protein foods
N/V can be reduced by taking with low-fat foods
Question:
Dopamine agonists prototype drugs
Answer:
Drug of choice for mild to moderate symptoms
pramipexole, ropinirole, rotigotine and apomorphine.
Question:
Tolcapone adverse effects
Answer:
Used only if safer drugs are ineffective
Intensifies levodopa related effects including dyskinesias, orthostatic
hypotension, hallucinations
, Question:
Black box warning for Tolcapone
Answer:
Live failure
Question:
Side effects of dopamine agonists
Answer:
N/V
Drowsiness
Dyskinesias (tics)
Ortho hypotension
Darkening of urine and sweat
Psychosis
Question:
Dopamine agonist MOA
Answer:
stimulate dopamine receptors in the brain without enzymatic conversion
