UWSA 2 UPDATED QUESTIONS AND ANSWERS RATED
A+
✔✔how does tetanospasmin get to CNS? - ✔✔retrograde transport
✔✔presentation of tetanus? - ✔✔construction worker with jaw pain
✔✔what is present in the window phase of HBV? - ✔✔Hbc-IgM
✔✔what is inflammed in the psoas test of appendicitis? - ✔✔the psoas
✔✔what is a symptom of one of the familial hyperlipidemias? - ✔✔corneal arcus
✔✔xanthomas in type 3 familial hyperlipidemia? - ✔✔tuberoeruptive
palmar
✔✔growth factor in atheromas? - ✔✔PDGF
FGF
✔✔three things pdgf does? - ✔✔vascular remodeling
smooth muscle cell migration
fibroblasts
✔✔what is a symptom of type 1 hyperlipidemia? - ✔✔lipemia retinalis
✔✔histofinding in liposarcomas? - ✔✔scalloping of the membrane
✔✔what is the triad of horner's syndrome? all are due to loss of what? - ✔✔miosis
anhidrosis
ptosis;
loss of SANS to the eye
✔✔which ganglia supplies the parotid gland? - ✔✔otic
✔✔where is aquaporin 2 located before ADH release? - ✔✔stored in vesicles in the
cytoplasm
✔✔side effect of all antipsychotics? - ✔✔QT prolongation
✔✔side effects of the two low potency antipsychotics? - ✔✔chlorpromazine - Corneal
deposits
Thioridazine - retinal deposits
,✔✔what is meckels an example of? - ✔✔choristoma
✔✔what is a choristoma? - ✔✔normal tissue in an abnormal location
✔✔how can meckels present? - ✔✔brisk painless GI bleedig
✔✔what makes HCM quieter? - ✔✔increase in preload and afterload
✔✔what mimics HCM in the effects of preload and afterload? - ✔✔MVP, becomes
better with increased preload and afterload
✔✔where do mitral valves open and close in wiggers? - ✔✔
✔✔what can widen S2 splitting? - ✔✔RBBB
pulmonary stenosis
✔✔immunoglobulins low in CVID? - ✔✔all
✔✔complications of CVID? - ✔✔bacterial
enteroviral
giardia
AI
lymphoma
bronchiectassi
✔✔PE finding in bruton agammaglobulinemia? - ✔✔absent tonsils
✔✔what is accuracy defined as? - ✔✔area under the ROC curve
TP + TN / everything
✔✔axes of the ROC curve? - ✔✔sensitvity - y
1 - specificity - x
✔✔only familial tumor disease that is not a tumor suppressor loss? - ✔✔MEN2 - RET
✔✔side effects of steroids? - ✔✔avascular necrosis of the femur
DM
osteoporosis
psychosis
cataracts
✔✔what degredation pathway does alkaptonuria occur in? - ✔✔in tyrosine and
phenylalaine
, ✔✔what is the pigment deposition in alkaptuonuria called? - ✔✔ochonrosis
✔✔what is the susbtantia nigra located next to? - ✔✔corticobulbar tract
✔✔what electrolyte changes occur in ischemia? which is the hallmark of ischemic
injury? - ✔✔K leaves cells;
Na, Ca, and Bicarb enter
intracellular Ca is the hallmark
✔✔three stimuli for the JG cell? - ✔✔decreased NaCl sensing by macula densa
decreased pressured at afferent
Beta stimulation
✔✔what is the proper marker of fetal lung maturity? - ✔✔lecithin: sphingomyelin ratio of
2:1
✔✔mutation in factor V leiden? explain - ✔✔G to A
causes arginine to glutamin at 506
✔✔sxs of factor V leiden? - ✔✔DVT
cerebral vein thrombosis
recurrent pregnancy loss
✔✔unique symptom of homocytseine from marfan? - ✔✔homocysteine has intellectual
disability
✔✔what level of a CT scan is the pancreas found? - ✔✔L2
✔✔where are most abdominal aortic aneurysm? - ✔✔inferior to renal vessels
✔✔what decreases the volume distribution of a drug? - ✔✔being bound to albumin
✔✔why can heparin be used in pregnancy? - ✔✔its water soluble, so doest cross
✔✔what does gonorrhea have? function - ✔✔OPA - binds surface
✔✔how are picornaviruses synthesized? - ✔✔RNA is made into 1 large polypeptide
which is cleaved by proteases into proteins
✔✔how are ganciclovir and acyclovir similar? - ✔✔both need phosphorylation by host
viral kinases
A+
✔✔how does tetanospasmin get to CNS? - ✔✔retrograde transport
✔✔presentation of tetanus? - ✔✔construction worker with jaw pain
✔✔what is present in the window phase of HBV? - ✔✔Hbc-IgM
✔✔what is inflammed in the psoas test of appendicitis? - ✔✔the psoas
✔✔what is a symptom of one of the familial hyperlipidemias? - ✔✔corneal arcus
✔✔xanthomas in type 3 familial hyperlipidemia? - ✔✔tuberoeruptive
palmar
✔✔growth factor in atheromas? - ✔✔PDGF
FGF
✔✔three things pdgf does? - ✔✔vascular remodeling
smooth muscle cell migration
fibroblasts
✔✔what is a symptom of type 1 hyperlipidemia? - ✔✔lipemia retinalis
✔✔histofinding in liposarcomas? - ✔✔scalloping of the membrane
✔✔what is the triad of horner's syndrome? all are due to loss of what? - ✔✔miosis
anhidrosis
ptosis;
loss of SANS to the eye
✔✔which ganglia supplies the parotid gland? - ✔✔otic
✔✔where is aquaporin 2 located before ADH release? - ✔✔stored in vesicles in the
cytoplasm
✔✔side effect of all antipsychotics? - ✔✔QT prolongation
✔✔side effects of the two low potency antipsychotics? - ✔✔chlorpromazine - Corneal
deposits
Thioridazine - retinal deposits
,✔✔what is meckels an example of? - ✔✔choristoma
✔✔what is a choristoma? - ✔✔normal tissue in an abnormal location
✔✔how can meckels present? - ✔✔brisk painless GI bleedig
✔✔what makes HCM quieter? - ✔✔increase in preload and afterload
✔✔what mimics HCM in the effects of preload and afterload? - ✔✔MVP, becomes
better with increased preload and afterload
✔✔where do mitral valves open and close in wiggers? - ✔✔
✔✔what can widen S2 splitting? - ✔✔RBBB
pulmonary stenosis
✔✔immunoglobulins low in CVID? - ✔✔all
✔✔complications of CVID? - ✔✔bacterial
enteroviral
giardia
AI
lymphoma
bronchiectassi
✔✔PE finding in bruton agammaglobulinemia? - ✔✔absent tonsils
✔✔what is accuracy defined as? - ✔✔area under the ROC curve
TP + TN / everything
✔✔axes of the ROC curve? - ✔✔sensitvity - y
1 - specificity - x
✔✔only familial tumor disease that is not a tumor suppressor loss? - ✔✔MEN2 - RET
✔✔side effects of steroids? - ✔✔avascular necrosis of the femur
DM
osteoporosis
psychosis
cataracts
✔✔what degredation pathway does alkaptonuria occur in? - ✔✔in tyrosine and
phenylalaine
, ✔✔what is the pigment deposition in alkaptuonuria called? - ✔✔ochonrosis
✔✔what is the susbtantia nigra located next to? - ✔✔corticobulbar tract
✔✔what electrolyte changes occur in ischemia? which is the hallmark of ischemic
injury? - ✔✔K leaves cells;
Na, Ca, and Bicarb enter
intracellular Ca is the hallmark
✔✔three stimuli for the JG cell? - ✔✔decreased NaCl sensing by macula densa
decreased pressured at afferent
Beta stimulation
✔✔what is the proper marker of fetal lung maturity? - ✔✔lecithin: sphingomyelin ratio of
2:1
✔✔mutation in factor V leiden? explain - ✔✔G to A
causes arginine to glutamin at 506
✔✔sxs of factor V leiden? - ✔✔DVT
cerebral vein thrombosis
recurrent pregnancy loss
✔✔unique symptom of homocytseine from marfan? - ✔✔homocysteine has intellectual
disability
✔✔what level of a CT scan is the pancreas found? - ✔✔L2
✔✔where are most abdominal aortic aneurysm? - ✔✔inferior to renal vessels
✔✔what decreases the volume distribution of a drug? - ✔✔being bound to albumin
✔✔why can heparin be used in pregnancy? - ✔✔its water soluble, so doest cross
✔✔what does gonorrhea have? function - ✔✔OPA - binds surface
✔✔how are picornaviruses synthesized? - ✔✔RNA is made into 1 large polypeptide
which is cleaved by proteases into proteins
✔✔how are ganciclovir and acyclovir similar? - ✔✔both need phosphorylation by host
viral kinases
