NMT 3210 | EVERY QUESTION SOLVED | EVERY
SCORE SECURED!
How long does it take for a cell to repair? - Answer: 24 hours
The more non-differentiated
Or actively dividing a cell is,
The more radiosensitive it is
And... The more differentiated or
Mitotically fixed a cell is,
The more radioresistant it is.
Except mature
Lymphocytes. - Answer: Direct and Indirect effects
Summed up in Law of Bergonie
And Tribondeau
-All or none response to
Radiation: random or
Statistical
-No threshold - can result
From a single interaction
-Probability increases with
Dose
-Severity does not increase
With dose - Answer: Stochastic effect
-Collective injury to a number
1
APPHIA - Crafted with Care and Precision for Academic Excellence.
,Of cells
-Non-linear w/Known
Thresholds
-Severity of effect increases
With dose - Answer: Deterministic effect
___________ effect examples are Cancer, Leukemia, Genetic damage appears in
offspring - Answer: stochastic
Stochastic effects can have long latent periods. Therefore, also known as - Answer:
Late effects
______-______ rem enough to cause effect on embryo - Answer: 5-15
Fetus is generally less radiosensitive after week _____ - Answer: 20
______ Trimester is most sensitive - Answer: 1st
Occupational dose limit to fetus is _____ rem/ gestation - Answer: 0.5
What kind of exposure is a High dose of radiation delivered
Within a short time: 500 rem for 10 sec? (also deterministic) - Answer: Acute
Short term Deterministic are seen as - Answer: early effects
Erythema - skin reddening (sunburn), depilation - hair loss, blood changes, diarrhea,
fever are signs of _________ effects - Answer: early
2
APPHIA - Crafted with Care and Precision for Academic Excellence.
, Ataracts, fibrosis, degenerative diseases are signs of _______ term and
______________ effects - Answer: Long, deterministic
Acute Effects are also______________ ____________
-Whole body
-High level exposure >100rads
-Lethal/near lethal syndromes (Hematologic or BMS, Gastrointestinal,CNS) - Answer:
Early effects
-Results from damage to the stem cells in the bone marrow and
Lymphatic organs
-usually occurs above doses of 2 Gy/200 rad
-results in infections and hemorrhage due to granulo- and
Thrombocytopenia.
-Death occurs within 4-5 weeks
Acute (100-1000 rad (1000 lethal), Prodromal stage: nausea vomiting, Latent period 3-5
weeks, Manifest illness: lose WBC/RBC forming
Capacity, Die from infection, electrolyte imbalance) - Answer: The Hematopoietic
Syndrome (Bone Marrow Syndrome BMS)
-Occurs when doses exceed 6 Gy/600rad
-Loss of intestinal stem cells leads to a breakdown of the intestinal/vascular barrier
-Sepsis and death within 5-8 days.
Acute (600-5000 rad, Prodromal stage: nausea/vomiting/diarrhea, Latent period 5 days,
Manifest illness: lose lining of GI tract, Die from dehydration, sepsis) - Answer: The
Gastrointestinal Syndrome (GIS)
3
APPHIA - Crafted with Care and Precision for Academic Excellence.
SCORE SECURED!
How long does it take for a cell to repair? - Answer: 24 hours
The more non-differentiated
Or actively dividing a cell is,
The more radiosensitive it is
And... The more differentiated or
Mitotically fixed a cell is,
The more radioresistant it is.
Except mature
Lymphocytes. - Answer: Direct and Indirect effects
Summed up in Law of Bergonie
And Tribondeau
-All or none response to
Radiation: random or
Statistical
-No threshold - can result
From a single interaction
-Probability increases with
Dose
-Severity does not increase
With dose - Answer: Stochastic effect
-Collective injury to a number
1
APPHIA - Crafted with Care and Precision for Academic Excellence.
,Of cells
-Non-linear w/Known
Thresholds
-Severity of effect increases
With dose - Answer: Deterministic effect
___________ effect examples are Cancer, Leukemia, Genetic damage appears in
offspring - Answer: stochastic
Stochastic effects can have long latent periods. Therefore, also known as - Answer:
Late effects
______-______ rem enough to cause effect on embryo - Answer: 5-15
Fetus is generally less radiosensitive after week _____ - Answer: 20
______ Trimester is most sensitive - Answer: 1st
Occupational dose limit to fetus is _____ rem/ gestation - Answer: 0.5
What kind of exposure is a High dose of radiation delivered
Within a short time: 500 rem for 10 sec? (also deterministic) - Answer: Acute
Short term Deterministic are seen as - Answer: early effects
Erythema - skin reddening (sunburn), depilation - hair loss, blood changes, diarrhea,
fever are signs of _________ effects - Answer: early
2
APPHIA - Crafted with Care and Precision for Academic Excellence.
, Ataracts, fibrosis, degenerative diseases are signs of _______ term and
______________ effects - Answer: Long, deterministic
Acute Effects are also______________ ____________
-Whole body
-High level exposure >100rads
-Lethal/near lethal syndromes (Hematologic or BMS, Gastrointestinal,CNS) - Answer:
Early effects
-Results from damage to the stem cells in the bone marrow and
Lymphatic organs
-usually occurs above doses of 2 Gy/200 rad
-results in infections and hemorrhage due to granulo- and
Thrombocytopenia.
-Death occurs within 4-5 weeks
Acute (100-1000 rad (1000 lethal), Prodromal stage: nausea vomiting, Latent period 3-5
weeks, Manifest illness: lose WBC/RBC forming
Capacity, Die from infection, electrolyte imbalance) - Answer: The Hematopoietic
Syndrome (Bone Marrow Syndrome BMS)
-Occurs when doses exceed 6 Gy/600rad
-Loss of intestinal stem cells leads to a breakdown of the intestinal/vascular barrier
-Sepsis and death within 5-8 days.
Acute (600-5000 rad, Prodromal stage: nausea/vomiting/diarrhea, Latent period 5 days,
Manifest illness: lose lining of GI tract, Die from dehydration, sepsis) - Answer: The
Gastrointestinal Syndrome (GIS)
3
APPHIA - Crafted with Care and Precision for Academic Excellence.
