CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Part 1 — Disease Prevention & Health Promotion (5 items)
Item 1
Reference: Ch. 1 — Disease Prevention & Health Promotion —
Immunizations
Question: A 68-year-old man with well-controlled type 2
diabetes presents for routine care. Which immunization should
be prioritized at this visit to reduce risk of invasive
pneumococcal disease?
A. Live attenuated influenza vaccine (nasal)
B. Pneumococcal conjugate vaccine (PCV) followed by
,polysaccharide vaccine (PPSV) per age-based schedule
C. Tetanus booster only if last dose > 10 years
D. Single dose of herpes zoster vaccine regardless of prior
vaccination history
Correct Answer: B
Rationale — Correct: Older adults and those with diabetes
should receive pneumococcal vaccination per age- and risk-
based schedules; CMDT emphasizes sequential/conjugate +
polysaccharide strategies to maximize protection.
accessmedicine.mhmedical.com
Rationale — A: The intranasal live influenza vaccine is
contraindicated in older adults; inactivated injectable influenza
vaccine is preferred. accessmedicine.mhmedical.com
Rationale — C: Tetanus boosters are given based on wound risk
and time since last dose; not the highest priority for
pneumococcal risk reduction. accessmedicine.mhmedical.com
Rationale — D: Herpes zoster vaccine is recommended for older
adults but addressing pneumococcal protection is higher
priority to prevent invasive disease in this patient.
accessmedicine.mhmedical.com
Teaching Point: Prioritize age/risk-based pneumococcal
vaccination for adults ≥65 or with chronic disease.
Citation (Simplified APA): Papadakis et al. (2025). CURRENT
Medical Diagnosis & Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
,Item 2
Reference: Ch. 1 — Disease Prevention & Health Promotion —
Cancer Screening
Question: A 52-year-old woman with no symptoms asks which
cancer screening is most likely to reduce mortality and should
be discussed now. Which screening does CMDT emphasize as
evidence-based for average-risk women in this age group?
A. Annual mammography starting at 50 until 70
B. Colonoscopy at 10-year intervals starting at age 50 (or earlier
if risk factors)
C. Pap smear alone every 3 years regardless of HPV testing
D. Routine CA-125 screening for ovarian cancer
Correct Answer: B
Rationale — Correct: Colon cancer screening (e.g., colonoscopy
intervals per guidelines) is a high-impact, mortality-reducing
screening for average-risk adults and should be addressed in
this age group. CMDT highlights colorectal cancer screening.
accessmedicine.mhmedical.com
Rationale — A: Mammography recommendations vary by
guideline; CMDT notes shared decision-making about
start/intervals rather than reflexive annual screening for all
women. accessmedicine.mhmedical.com
Rationale — C: Pap smear strategies depend on age and HPV
co-testing; "Pap alone every 3 years" is not the universal answer
without considering HPV testing.
accessmedicine.mhmedical.com
Rationale — D: Routine CA-125 screening for ovarian cancer is
, not recommended for average-risk, asymptomatic women.
accessmedicine.mhmedical.com
Teaching Point: Colorectal cancer screening reduces mortality;
follow age-appropriate screening schedules.
Citation (Simplified APA): Papadakis et al. (2025). CURRENT
Medical Diagnosis & Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
Item 3
Reference: Ch. 1 — Disease Prevention & Health Promotion —
Lifestyle Counseling (Smoking Cessation)
Question: A 45-year-old man who smokes asks for the single
most effective long-term intervention to reduce his risk of
smoking-related disease. According to CMDT, which approach
has the best evidence for sustained cessation?
A. Brief advice from provider only
B. Nicotine replacement therapy (NRT) combined with
behavioral counseling
C. Self-help pamphlet and follow-up in 6 months
D. E-cigarettes as first-line cessation therapy
Correct Answer: B
Rationale — Correct: CMDT endorses combining
pharmacotherapy (NRT, varenicline, or bupropion) with
behavioral counseling as the most effective approach to long-
term smoking cessation. accessmedicine.mhmedical.com
Rationale — A: Brief advice improves quit attempts but is less
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Part 1 — Disease Prevention & Health Promotion (5 items)
Item 1
Reference: Ch. 1 — Disease Prevention & Health Promotion —
Immunizations
Question: A 68-year-old man with well-controlled type 2
diabetes presents for routine care. Which immunization should
be prioritized at this visit to reduce risk of invasive
pneumococcal disease?
A. Live attenuated influenza vaccine (nasal)
B. Pneumococcal conjugate vaccine (PCV) followed by
,polysaccharide vaccine (PPSV) per age-based schedule
C. Tetanus booster only if last dose > 10 years
D. Single dose of herpes zoster vaccine regardless of prior
vaccination history
Correct Answer: B
Rationale — Correct: Older adults and those with diabetes
should receive pneumococcal vaccination per age- and risk-
based schedules; CMDT emphasizes sequential/conjugate +
polysaccharide strategies to maximize protection.
accessmedicine.mhmedical.com
Rationale — A: The intranasal live influenza vaccine is
contraindicated in older adults; inactivated injectable influenza
vaccine is preferred. accessmedicine.mhmedical.com
Rationale — C: Tetanus boosters are given based on wound risk
and time since last dose; not the highest priority for
pneumococcal risk reduction. accessmedicine.mhmedical.com
Rationale — D: Herpes zoster vaccine is recommended for older
adults but addressing pneumococcal protection is higher
priority to prevent invasive disease in this patient.
accessmedicine.mhmedical.com
Teaching Point: Prioritize age/risk-based pneumococcal
vaccination for adults ≥65 or with chronic disease.
Citation (Simplified APA): Papadakis et al. (2025). CURRENT
Medical Diagnosis & Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
,Item 2
Reference: Ch. 1 — Disease Prevention & Health Promotion —
Cancer Screening
Question: A 52-year-old woman with no symptoms asks which
cancer screening is most likely to reduce mortality and should
be discussed now. Which screening does CMDT emphasize as
evidence-based for average-risk women in this age group?
A. Annual mammography starting at 50 until 70
B. Colonoscopy at 10-year intervals starting at age 50 (or earlier
if risk factors)
C. Pap smear alone every 3 years regardless of HPV testing
D. Routine CA-125 screening for ovarian cancer
Correct Answer: B
Rationale — Correct: Colon cancer screening (e.g., colonoscopy
intervals per guidelines) is a high-impact, mortality-reducing
screening for average-risk adults and should be addressed in
this age group. CMDT highlights colorectal cancer screening.
accessmedicine.mhmedical.com
Rationale — A: Mammography recommendations vary by
guideline; CMDT notes shared decision-making about
start/intervals rather than reflexive annual screening for all
women. accessmedicine.mhmedical.com
Rationale — C: Pap smear strategies depend on age and HPV
co-testing; "Pap alone every 3 years" is not the universal answer
without considering HPV testing.
accessmedicine.mhmedical.com
Rationale — D: Routine CA-125 screening for ovarian cancer is
, not recommended for average-risk, asymptomatic women.
accessmedicine.mhmedical.com
Teaching Point: Colorectal cancer screening reduces mortality;
follow age-appropriate screening schedules.
Citation (Simplified APA): Papadakis et al. (2025). CURRENT
Medical Diagnosis & Treatment 2026 (65th Ed.). Ch. 1.
accessmedicine.mhmedical.com
Item 3
Reference: Ch. 1 — Disease Prevention & Health Promotion —
Lifestyle Counseling (Smoking Cessation)
Question: A 45-year-old man who smokes asks for the single
most effective long-term intervention to reduce his risk of
smoking-related disease. According to CMDT, which approach
has the best evidence for sustained cessation?
A. Brief advice from provider only
B. Nicotine replacement therapy (NRT) combined with
behavioral counseling
C. Self-help pamphlet and follow-up in 6 months
D. E-cigarettes as first-line cessation therapy
Correct Answer: B
Rationale — Correct: CMDT endorses combining
pharmacotherapy (NRT, varenicline, or bupropion) with
behavioral counseling as the most effective approach to long-
term smoking cessation. accessmedicine.mhmedical.com
Rationale — A: Brief advice improves quit attempts but is less
