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NBME CBSE Actual Test Questions and Answers 2024/2025 | USMLE Step 1 Medical Exam Quiz Bank (All Correct Answers)

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This NBME CBSE 2024/2025 quiz bank contains realistic practice questions and verified correct answers designed to match the latest USMLE Step 1 and Comprehensive Basic Science Exam (CBSE) format. It covers all high-yield medical subjects—anatomy, physiology, pathology, pharmacology, microbiology, and biochemistry—with clear explanations to strengthen your understanding and boost your exam performance. Ideal for medical students preparing for Step 1 or NBME self-assessments, this resource is graded, updated, and review-ready for 2024/2025.

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Institution
Cbse
Course
Cbse

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NBME CBSE ACTUAL TEST QUESTIONS AND
ANSWERS 2024/2025 | QUIZBANK WITH 100%
CORRECT ANSWERS




Decreased Osteoclast Activity
62 year old woman - osteoporosis – a
bisphosphonate is prescribed. The
expected beneficial effect of the drug is
due to which of the following?
Cohot Study of elderly women – relative Statistically Significant Overall Increase Risk
risk ratio for hip fractures among those
who exercise regularly is 1.2 (95%
confidence interval of 1.1 to 1.8). Which of
the following is the conclusion about the
effect of exercise on the risk of hip
fracture?
52 year old man goes to ER with chest pain Increased nitric oxide concentration
radiating to his jaw while shoveling snow.
Pulse is 80/min and blood pressure is
130/70. The most immediate treatment
mechanism of action?
24 year old woman – spilled hot grease on a. Vascular Endothelial Growth Factor
her left leg while working at a fast-food VEGF – stimulates angiogenesiss.
restaurant. Exam of leg shows 7cm pink, TYPE III Collagen = Blood Vessels – early wound repair
soft, granular, edematous wound. The
formation of this tissue was most likely
caused by increased activity of which?
27 year old man- MVC – skull x-ray shows a a. Adenylyl Cyclase
linear, nondepressed basal skull fracture – Adenylate Cyclase – ATP – CAMP --
increased serum osm and decreased urin PROTEKINASE A -- Ca
osm. Following desmopressin urine osm v2
increases. Desmopressin’s effect is due to
the activation of which ofthe following?

, A 10 month old boy – 4 day history of fever Mediation of Cell Entry via a fusion protein
and cough. He attends day care center.
Chest exam shows intercostal retractions
along with bilateral, diffuse wheezes and
expiratory rhonchi. The infectious agent
most likely has which of the following
properties?

A 17 year old girl in ED – 15 minutes after B2- Agonist
being stung by a bee. Mild light
headedness but no difficulty swallowing-
Bilateral wheezing - Which is most
appropriate pharmacotherapy for this
patient?

14 year old boy - 2 day history of sore Infectious Mononucleosis
throat and fever that peaks in late
afternoon. 1 week of fatigue. He recentaly
had sex with one partner. Physical exam
show cervical lymphadenopathy and
pharyngeal erythema with a creamy
exudate. DX?

57 year old man – radiation therapy for G1
squamous cell carcinoma of the lung.
Despite therapy, tumor increases in size
and he dies 6 months later. The
progressive tumor growth is due to a
defect in cell cycle arrest in which of the
following phases of cell cycle?

28 year old – lived in sub-Saharan Africa – Schistosomiasis
until he came to the US. Temp of 100.4 –
imaging shows bilateral hydroureter and
hydronephrosis. Biopsy shows marked
fibrosis and scattered granulomas. DX?

A couple with a family history of a- 50%
thalassemia. Woman has one gene
deletion and man has two gene deletion. If
the two gene is trans – what percentage of
offspring will have a two gene deletion?

previously healthy 40 year brought to Thrombotic Thrombocytopenia Purpura
emergency department by her husband – 2
day history of fever, lethargy, confusion. PE
shows scattered petechiae and
ecchymoses over the lower extremities –
3+ polychromasia and 3+ schistocytes and
Low platelets Dx?

16 year old boy – is admitted to the ER Hemopneumpothorax under tension
because of a knife wound to the left side of
his chest. An X-ray of the chest shows an
air-fluid level in the left side of the chest,
partial collapse of the left lung, and the
elevation of the stomach bubble. The
mediastinum is midline. DX?

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Institution
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Course
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