Pharmacokinetics Exam Questions and Answers 100% Pass

Pharmacokinetics Exam Questions and
Answers 100% Pass


Four principles of pharmacokinetics -

[ANSWER]: - Absorption

- Distribution

- Metabolism

- Excretion




QUESTION: What is pharmacokinetics? -

[ANSWER]: What the body does to the drug




QUESTION: What is biotransformation? -

[ANSWER]: Changing a compound into something more usable by the

body

,QUESTION: 5 Factors that impact the degree of drug absorption -

[ANSWER]: 1) route of administration

2) solubility of drug administered

3) conditions at site of absorption

4) degree of ionization of the drug

5) bioavailability




QUESTION: Why does the solubility of a drug matter in relation to

drug absorption? -

[ANSWER]: More lipid soluble, aka lipophilic (lipid LOVING) can pass

through cell membranes easily (remember cell membranes are composed

of a lipid bilayer).




QUESTION: What effect does ionization have on drug absorption? -

, [ANSWER]: Drug absorption is greater if the drug is in non-ionized,

lipid soluble form. The ionized form is water soluble and possesses an

electrical charge which is repelled by the cell membrane.




QUESTION: Routes of administration: name the fastest to the slowest

route in terms of onset -

[ANSWER]: Onset (quickest - slowest) : IV>IM>SC>oral




QUESTION: Routes of administration: name the shortest to the longest

route in terms of duration -

[ANSWER]: Duration (shortest to longest) : IV>IM>SC>oral




QUESTION: Advantages of oral route of administration -

[ANSWER]: 1) Convenient

2) Economical




QUESTION: Disadvantages of oral route of administration -