Unit 8 - Women's Health
____ found in Natazia®. This fourth-generation progestin is a testosterone derivative without the
K+-sparing effects. - ANS -Dienogest
\-Applied to certain locations any day of the cycle, changed every 8th day, removed the last 7
days.
-Slowly releases combined E/P
-Releases about 60% more of the hormones compared to pills
-Unpredictable absorption in obese females - ANS -Ortho Evra® patch
\-Self-applied
-Used for 21 days, removed for 7 days to allow for withdrawal bleeding
-Could be removed during sex, to be replaced within 3
hours - ANS -NuvaRing® vaginal ring
\-This is NOT abortion.
-This is a post-coital contraception in cases of unwanted pregnancy as in failed barrier method,
rape, non-use of contraceptives
-Highest efficacy if used as soon as possible up to 5 days - ANS -Plan B
\A bone disorder characterized by low bone density, impaired bone architecture, and
compromised bone strength that predisposes a person to increased fracture risk. - ANS
-Osteoporosis
\A thyroid hormone that inhibits osteoclastic bone resorption. - ANS -Calcitonin
\Advantages of:
-Can be used by women with contraindications to estrogen
-Many long-term options that require little attention
-Can be used by breast-feeding women - ANS -progesterone only contraception
\Always use the lowest dose, for the shortest duration: - ANS -HRT
\Antiresorptive therapy side effects:
-nasal: rhinitis and flu-like symptoms are most common, epistaxis
-injections: nausea, flushing, local inflammation - ANS -Calcitonin
\Antiresorptive therapy side effects: flatulence, eczema, cellulitis, and increased urinary and
respiratory tract infections. - ANS -RANK Ligand Inhibitor
\Antiresorptive therapy side effects: Hot flushes, leg pain, spasms or cramps. Venous
thromboembolism - ANS -EEAs
\Antiresorptive therapy side effects: Orthostatic hypotension with first few injections, pain at
injection site, nausea, headache, dizziness, leg cramps. - ANS -Formation (Anabolic) Therapy
\Any of the following 4 methods can be used:
-Combined E/P pills
-Progesterone-only pills
-Anti-progestins: mifepristone (Mifeprex®)
-Copper IUD - ANS -Plan B
\Bacterial Vaginosis tx: - ANS -Metronidazole Or Clindamycin [Topical or oral]
\Benefits of:
, -Favorable effect on menstrual flow: more predictable/regular, less breakthrough bleeding, less
cramps, lighter, shorter
-Decreased risk of ovarian cancer, ovarian cysts, PID, and acne - ANS -COCs
\Calcitonin-salmon is available in two forms: - ANS -nasal spray
s.c. injections
\Chlamydia tx - ANS -Azithromycin OR Doxycycline
\Clinical Implication: Advise the patient to take the medication with a full glass of water and
remain sitting upright for at least 30 min to avoid esophagitis - ANS -Bisphosphonates
\COCs can be divided into 3 groups: - ANS --Monophasic
-Biphasic
-Triphasic
\COCs: Pills - ANS -Combined Oral Contraceptives
\Combination HRT Therapy:
Women with intact uterus, should receive progesterone [____] with estrogen to decrease the
risk of endometrial carcinoma. - ANS -Progesterone, micronized (Prometrium®)
\Combination HRT Therapy:
Women with intact uterus, should receive progesterone [Progesterone, micronized
(Prometrium®)] with estrogen to decrease the risk of: - ANS -endometrial carcinoma.
\Combined estrogen/progesterone first-generation: ____ found in Brevicon® - ANS
-Norethindrone
\Combined estrogen/progesterone second-generation: ____ and ____ found in Lo/Ovral®,
Seasonale®. More potent, longer t1/2. Less spotting, less androgenic. - ANS -Norgestrel,
levonorgestrel
\Combined estrogen/progesterone third-generation: ____ found in Desogen®. - ANS
-Desogestrel
\Copper IUD is also called: - ANS -Paragard®
\Dienogest found in Natazia®. This fourth-generation progestin is a ____ derivative without the
K+-sparing effects. - ANS -testosterone
\Dienogest found in Natazia®. This fourth-generation progestin is a testosterone derivative
without the ____-sparing effects. - ANS -K+
\Disadvantages of:
-More chance for irregular breakthrough bleeding (especially at the start of use)
-The pills have to be taken exactly same time each day
-Side effects (related to the type): depression, weight gain, hair loss, acne - ANS -progesterone
only contraception
\EAAs - ANS -Mixed Estrogen Agonists Antagonists
\Emergency Contraception: - ANS -Plan B
\Estrogen only treatment during menopause might cause: - ANS -endometrial carcinoma
\Estrogen or progesterone?
Activates clotting mechanisms - ANS -estrogen
\Estrogen or progesterone?
Decreases SHBG (thus might worsen acne) - ANS -progesterone
\Estrogen or progesterone?
Endometrial hyperplasia - ANS -estrogen
____ found in Natazia®. This fourth-generation progestin is a testosterone derivative without the
K+-sparing effects. - ANS -Dienogest
\-Applied to certain locations any day of the cycle, changed every 8th day, removed the last 7
days.
-Slowly releases combined E/P
-Releases about 60% more of the hormones compared to pills
-Unpredictable absorption in obese females - ANS -Ortho Evra® patch
\-Self-applied
-Used for 21 days, removed for 7 days to allow for withdrawal bleeding
-Could be removed during sex, to be replaced within 3
hours - ANS -NuvaRing® vaginal ring
\-This is NOT abortion.
-This is a post-coital contraception in cases of unwanted pregnancy as in failed barrier method,
rape, non-use of contraceptives
-Highest efficacy if used as soon as possible up to 5 days - ANS -Plan B
\A bone disorder characterized by low bone density, impaired bone architecture, and
compromised bone strength that predisposes a person to increased fracture risk. - ANS
-Osteoporosis
\A thyroid hormone that inhibits osteoclastic bone resorption. - ANS -Calcitonin
\Advantages of:
-Can be used by women with contraindications to estrogen
-Many long-term options that require little attention
-Can be used by breast-feeding women - ANS -progesterone only contraception
\Always use the lowest dose, for the shortest duration: - ANS -HRT
\Antiresorptive therapy side effects:
-nasal: rhinitis and flu-like symptoms are most common, epistaxis
-injections: nausea, flushing, local inflammation - ANS -Calcitonin
\Antiresorptive therapy side effects: flatulence, eczema, cellulitis, and increased urinary and
respiratory tract infections. - ANS -RANK Ligand Inhibitor
\Antiresorptive therapy side effects: Hot flushes, leg pain, spasms or cramps. Venous
thromboembolism - ANS -EEAs
\Antiresorptive therapy side effects: Orthostatic hypotension with first few injections, pain at
injection site, nausea, headache, dizziness, leg cramps. - ANS -Formation (Anabolic) Therapy
\Any of the following 4 methods can be used:
-Combined E/P pills
-Progesterone-only pills
-Anti-progestins: mifepristone (Mifeprex®)
-Copper IUD - ANS -Plan B
\Bacterial Vaginosis tx: - ANS -Metronidazole Or Clindamycin [Topical or oral]
\Benefits of:
, -Favorable effect on menstrual flow: more predictable/regular, less breakthrough bleeding, less
cramps, lighter, shorter
-Decreased risk of ovarian cancer, ovarian cysts, PID, and acne - ANS -COCs
\Calcitonin-salmon is available in two forms: - ANS -nasal spray
s.c. injections
\Chlamydia tx - ANS -Azithromycin OR Doxycycline
\Clinical Implication: Advise the patient to take the medication with a full glass of water and
remain sitting upright for at least 30 min to avoid esophagitis - ANS -Bisphosphonates
\COCs can be divided into 3 groups: - ANS --Monophasic
-Biphasic
-Triphasic
\COCs: Pills - ANS -Combined Oral Contraceptives
\Combination HRT Therapy:
Women with intact uterus, should receive progesterone [____] with estrogen to decrease the
risk of endometrial carcinoma. - ANS -Progesterone, micronized (Prometrium®)
\Combination HRT Therapy:
Women with intact uterus, should receive progesterone [Progesterone, micronized
(Prometrium®)] with estrogen to decrease the risk of: - ANS -endometrial carcinoma.
\Combined estrogen/progesterone first-generation: ____ found in Brevicon® - ANS
-Norethindrone
\Combined estrogen/progesterone second-generation: ____ and ____ found in Lo/Ovral®,
Seasonale®. More potent, longer t1/2. Less spotting, less androgenic. - ANS -Norgestrel,
levonorgestrel
\Combined estrogen/progesterone third-generation: ____ found in Desogen®. - ANS
-Desogestrel
\Copper IUD is also called: - ANS -Paragard®
\Dienogest found in Natazia®. This fourth-generation progestin is a ____ derivative without the
K+-sparing effects. - ANS -testosterone
\Dienogest found in Natazia®. This fourth-generation progestin is a testosterone derivative
without the ____-sparing effects. - ANS -K+
\Disadvantages of:
-More chance for irregular breakthrough bleeding (especially at the start of use)
-The pills have to be taken exactly same time each day
-Side effects (related to the type): depression, weight gain, hair loss, acne - ANS -progesterone
only contraception
\EAAs - ANS -Mixed Estrogen Agonists Antagonists
\Emergency Contraception: - ANS -Plan B
\Estrogen only treatment during menopause might cause: - ANS -endometrial carcinoma
\Estrogen or progesterone?
Activates clotting mechanisms - ANS -estrogen
\Estrogen or progesterone?
Decreases SHBG (thus might worsen acne) - ANS -progesterone
\Estrogen or progesterone?
Endometrial hyperplasia - ANS -estrogen
