Test BankFor Abrams’ Clinical Drug Therapy Rationales fo
6
b
Nursing Practice 13th Edition (Version 2025/2026) Geralyn
Frandsen
,Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated through
the bloodstream to their sites of action in various body tissues, and eventually eliminated
from the body. Curative agents are given to cure a disease process. In this case, paroxeti
ne hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff
ects, such as sunscreen and local anesthetics, act mainly at the site of application. Paroxet
ine hydrochloride is not administered parenterally. Parenteral agents are administered sub
cutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
.hCaOt Mi s another name for this type o
b6
f medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
that have been chemically modified. Synthetic drugs are more standardized in their chemic
al characteristics, more consistent in their effects, and less likely to produce allergic react
ions. Biotechnology drugs involve manipulating DNA and RNA and recombining genes i
nto hybrid molecules that can be inserted into living organisms. Prototype drugs are the f
irst drug of a particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
, C. Anti-inflammatory
D. Antihypertensive
ANS: A
Rationale: Drugs are classified according to their effects on particular body systems, their
therapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
rvous system depressant and will produce this effect in the client. A central nervous syste
m stimulant increases attention and raises mood. An anti-
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
antihypertensive agent reduces blood pressure.
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs to whi
ch drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic namGeRoAfD
b6 teE
n SinBdO
b6 icO
atSesTt.hC
b6 b6eOdrug group (e.g., drugs with generic nam
es ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medicatio
ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur
etics are medications that increase urine output; diuretic is a broad classification, not a ge
neric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
not the generic name.
PTS: 1 REF: p. 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and
Drug Administration ANS: D
b6
, Rationale: The Food and Drug Administration approves drugs for over-the-
counter availability, including the transfer of drugs from prescription to OTC status, and
may require clinical trials to determine the safety and effectiveness of OTC use. The Pu
blic Health Service is regulated by the state to maintain the health of individual citizens
of the state. The Federal Trade Commission regulates imports and exports throughout the
nation. The Occupational Safety and Health Administration regulates safety within the wo
rkplace.
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma
nufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and anaboli
c steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powe
rs and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Ac
t restricted the importation, manufacture, sale, and use of opium, cocaine, marijuana, and
other drugs that the act d e f i Gn eRd Aa Ds E
naSrcBoO
tiO
b6csS
.TTh.eCSOhM
erley Amendment of 1912 prohibited
fraudulent claims of drug effectiveness.
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nurse is responsible for maintaining an accurate count and record of the controlled
substances on the nursing division. This nursing action is regulated by which U.S. law
or agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley
Amendment ANS: C
6
b
Nursing Practice 13th Edition (Version 2025/2026) Geralyn
Frandsen
,Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated through
the bloodstream to their sites of action in various body tissues, and eventually eliminated
from the body. Curative agents are given to cure a disease process. In this case, paroxeti
ne hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff
ects, such as sunscreen and local anesthetics, act mainly at the site of application. Paroxet
ine hydrochloride is not administered parenterally. Parenteral agents are administered sub
cutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
.hCaOt Mi s another name for this type o
b6
f medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
that have been chemically modified. Synthetic drugs are more standardized in their chemic
al characteristics, more consistent in their effects, and less likely to produce allergic react
ions. Biotechnology drugs involve manipulating DNA and RNA and recombining genes i
nto hybrid molecules that can be inserted into living organisms. Prototype drugs are the f
irst drug of a particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
, C. Anti-inflammatory
D. Antihypertensive
ANS: A
Rationale: Drugs are classified according to their effects on particular body systems, their
therapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
rvous system depressant and will produce this effect in the client. A central nervous syste
m stimulant increases attention and raises mood. An anti-
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
antihypertensive agent reduces blood pressure.
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs to whi
ch drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic namGeRoAfD
b6 teE
n SinBdO
b6 icO
atSesTt.hC
b6 b6eOdrug group (e.g., drugs with generic nam
es ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medicatio
ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur
etics are medications that increase urine output; diuretic is a broad classification, not a ge
neric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
not the generic name.
PTS: 1 REF: p. 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and
Drug Administration ANS: D
b6
, Rationale: The Food and Drug Administration approves drugs for over-the-
counter availability, including the transfer of drugs from prescription to OTC status, and
may require clinical trials to determine the safety and effectiveness of OTC use. The Pu
blic Health Service is regulated by the state to maintain the health of individual citizens
of the state. The Federal Trade Commission regulates imports and exports throughout the
nation. The Occupational Safety and Health Administration regulates safety within the wo
rkplace.
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma
nufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and anaboli
c steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powe
rs and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Ac
t restricted the importation, manufacture, sale, and use of opium, cocaine, marijuana, and
other drugs that the act d e f i Gn eRd Aa Ds E
naSrcBoO
tiO
b6csS
.TTh.eCSOhM
erley Amendment of 1912 prohibited
fraudulent claims of drug effectiveness.
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nurse is responsible for maintaining an accurate count and record of the controlled
substances on the nursing division. This nursing action is regulated by which U.S. law
or agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley
Amendment ANS: C
