NR 565 Week 1 Pharmacogenomics Discussion (Original Post, Responses)

In your initial post, respond to the following scenario (Hint: use the pharmgkb website to guide your responses): Before initiating abacavir, an anti-retroviral, for a newly diagnosed HIV positive patient the nurse practitioner orders HLA-B*5701 allele genetic testing. The test confirms that the patient carries the HLA-B*5701 allele. * Describe what these results mean. * Should the nurse practitioner prescribe abacavir in this case? If not, state why. A patient is prescribed antiplatelet therapy (clopidogrel) following an acute myocardial infarction (MI). Six months later, the patient suffers another acute MI. The patient has been adherent to therapy and the nurse practitioner suspects that clopidrogel may have been ineffective. How might genetic testing have been beneficial in this case? Identify 2 limitations of pharmacogenomics testing. Explain. Identify 2 ethical concerns of using pharmacogenomics testing. Explain.