COMLEX Level 1 Exam Material Newest
2025/2026 Complete Questions And
Correct Answers (Verified
Answers)|Brand New Version!
cysteine stone - ,,,answer,,,..- *Hexagonal* stones
- *Ground, glass appearance*
- *(+) urinary cyanide nitroprusside test
- Defect in renal transport of COLA: Cysteine, Ornithine, Lysine, Arginine
- Does NOT respond to shock wave therapy
angiodysplasia - ,,,answer,,,..most common cause of lower GI bleeding in
pt's >60
superior mesenteric artery - ,,,answer,,,..supplies the lower portion of the
duodenum, jejunum, ileum, cecum, ascending colon, and transverse
colon to the splenic flexure
pancreatic cancer - ,,,answer,,,..-usually arises in the *head* of the
pancreas
-is associated with *jaundice and pain* due to obstruction of the
common bile duct
- it is the *4th* most common cause of cancer
-has a very poor prognosis
,1. Calcium channel blockers--> specifically smooth muscle antagonists--
> SM dilation
2. Alpha adrenergic receptor blockers --> cause dilation of vessels instead
of constriction
3. Beta 2 agonists: causes dilation of smooth muscle vessels -
,,,answer,,,..Patients with GERD normally have a dysfunction with LES
sphincter tone that allows acid to reflux into the esophagus, thus drugs
that affect sphincter tone would make GERD worse. What are the name of
three drug categories that do this?
celiac disease - ,,,answer,,,..malabsorption syndrome caused by an
immune reaction to gliadian protein in gluten
-Tissue transglutaminase
-results in villous atrophy of small intestine mucosa and causes
steatorrhea, diarrhea, bloating and abdominal pain
-*also associated with other autoimmune disorders like hashimotos
thyroiditis*
make NPO, Place on an NG tube and suction obstruction out--> this will
usually resolve obstruction - ,,,answer,,,..after a patient comes to the ER
with sudden onset of pain and abdominal distention W/O peritoneal signs
and after x-ray you diagnose her with a small bowel obstruction. What do
you do next?
Low total calcium due to low albumin levels from cirrhosis (95% of Ca2+
is bound to albumin) and normal ionized Ca2+ because PTH regulates
free ionized Ca2+ independently--> that is why there are no signs go
hypocalcemia - ,,,answer,,,..In a patient with liver cirrhosis what calcium
levels would you expect to see?
Would there be signs of hypocalcemia--> tetany, paresthesias, abdominal
cramps?
,T5-T11 - ,,,answer,,,..where would you find a viserosomatic reflex
resulting in placatory changes of the pancreas?
Deferoxamine (Desferal) - ,,,answer,,,..iron chelating agent used in the
treatment of iron intoxication
short leg syndrome - ,,,answer,,,..when a patient presents with a flexible
scoliotic curve it is important to evaluate for...
inferior trunk--> encompasses broadmann areas 22,39,40 which are in
the temporal region - ,,,answer,,,..Infarct to what trunk of the Left MCA
results in Wernicke's aphasia?
Superior division--> encompasses brooks area, frontal eye field, primary
motor cortex and primary somatosensory cortex - ,,,answer,,,..Infarct to
what trunk of the Left MCA results in Broca's aphasia?
Osteosarcoma - ,,,answer,,,..bone tumor that is present in young adult
males that involves the metaphysis of the long bones
Ewing's sarcoma t(11;22) - ,,,answer,,,..bone tumor that is present in
young adult males that involves the *diaphysis(mid-shaft)* of the long
bones.
fibrosarcoma - ,,,answer,,,..malignant fibroblasts within a collagenous
matrix
chondrosarcoma - ,,,answer,,,..osseous sarcomas that affect older
patients and has a predilection for flat bones in the *shoulders and
pelvis*
tyrosine, due to a defect in phenylalanine hydroxylase - ,,,answer,,,..PKU
presents as failure to thrive, mental retardation, gapped teeth, etc. What
, is the amino acid that needs to be supplemented due to a defect in what
enzyme?
Rib 2 - ,,,answer,,,..where does the posterior scalene attach to?
Paclitaxel - ,,,answer,,,..used in the treatment of breast and ovarian
cancer
MOA: hyper stabilization of polymerized microtubules--> prevents the
breakdown of the mitotic spindle
restrictive barrier - ,,,answer,,,..maximum distance a patient can actually
move a joint, can be pathologic
narcissistic personality disorder - ,,,answer,,,..patterns of grandiosity,
need for admiration, lack of empathy for others
A carotid massage causes an increase in stretch of the carotid
baroreceptors which causes a reflexive PARASYM response which slows
down the conduction velocity through the AV node this slowing down
Heart Rate--> used in paroxysmal supra ventricular tachycardia -
,,,answer,,,..what does a carotid massage do and how does it affect the
AV node?
Chronic myelogenous leukemia t(9;22)--> Philly chx - ,,,answer,,,..a form
of leukemia characterized by the accumulation of abnormal, mature
granulocytes (granulocytes are a type of white blood cell), mild anemia,
thrombocytosis and basophilia. What is the associated chromosomal
translocation?
Burkitt's lymphoma t(8;14) - ,,,answer,,,..germinal B celll lymphoma that
is associated with a translocation between c-MYC and the Ig heavy chain
on which two chromosomes? It is endemic in the continent of Africa
which produces this
2025/2026 Complete Questions And
Correct Answers (Verified
Answers)|Brand New Version!
cysteine stone - ,,,answer,,,..- *Hexagonal* stones
- *Ground, glass appearance*
- *(+) urinary cyanide nitroprusside test
- Defect in renal transport of COLA: Cysteine, Ornithine, Lysine, Arginine
- Does NOT respond to shock wave therapy
angiodysplasia - ,,,answer,,,..most common cause of lower GI bleeding in
pt's >60
superior mesenteric artery - ,,,answer,,,..supplies the lower portion of the
duodenum, jejunum, ileum, cecum, ascending colon, and transverse
colon to the splenic flexure
pancreatic cancer - ,,,answer,,,..-usually arises in the *head* of the
pancreas
-is associated with *jaundice and pain* due to obstruction of the
common bile duct
- it is the *4th* most common cause of cancer
-has a very poor prognosis
,1. Calcium channel blockers--> specifically smooth muscle antagonists--
> SM dilation
2. Alpha adrenergic receptor blockers --> cause dilation of vessels instead
of constriction
3. Beta 2 agonists: causes dilation of smooth muscle vessels -
,,,answer,,,..Patients with GERD normally have a dysfunction with LES
sphincter tone that allows acid to reflux into the esophagus, thus drugs
that affect sphincter tone would make GERD worse. What are the name of
three drug categories that do this?
celiac disease - ,,,answer,,,..malabsorption syndrome caused by an
immune reaction to gliadian protein in gluten
-Tissue transglutaminase
-results in villous atrophy of small intestine mucosa and causes
steatorrhea, diarrhea, bloating and abdominal pain
-*also associated with other autoimmune disorders like hashimotos
thyroiditis*
make NPO, Place on an NG tube and suction obstruction out--> this will
usually resolve obstruction - ,,,answer,,,..after a patient comes to the ER
with sudden onset of pain and abdominal distention W/O peritoneal signs
and after x-ray you diagnose her with a small bowel obstruction. What do
you do next?
Low total calcium due to low albumin levels from cirrhosis (95% of Ca2+
is bound to albumin) and normal ionized Ca2+ because PTH regulates
free ionized Ca2+ independently--> that is why there are no signs go
hypocalcemia - ,,,answer,,,..In a patient with liver cirrhosis what calcium
levels would you expect to see?
Would there be signs of hypocalcemia--> tetany, paresthesias, abdominal
cramps?
,T5-T11 - ,,,answer,,,..where would you find a viserosomatic reflex
resulting in placatory changes of the pancreas?
Deferoxamine (Desferal) - ,,,answer,,,..iron chelating agent used in the
treatment of iron intoxication
short leg syndrome - ,,,answer,,,..when a patient presents with a flexible
scoliotic curve it is important to evaluate for...
inferior trunk--> encompasses broadmann areas 22,39,40 which are in
the temporal region - ,,,answer,,,..Infarct to what trunk of the Left MCA
results in Wernicke's aphasia?
Superior division--> encompasses brooks area, frontal eye field, primary
motor cortex and primary somatosensory cortex - ,,,answer,,,..Infarct to
what trunk of the Left MCA results in Broca's aphasia?
Osteosarcoma - ,,,answer,,,..bone tumor that is present in young adult
males that involves the metaphysis of the long bones
Ewing's sarcoma t(11;22) - ,,,answer,,,..bone tumor that is present in
young adult males that involves the *diaphysis(mid-shaft)* of the long
bones.
fibrosarcoma - ,,,answer,,,..malignant fibroblasts within a collagenous
matrix
chondrosarcoma - ,,,answer,,,..osseous sarcomas that affect older
patients and has a predilection for flat bones in the *shoulders and
pelvis*
tyrosine, due to a defect in phenylalanine hydroxylase - ,,,answer,,,..PKU
presents as failure to thrive, mental retardation, gapped teeth, etc. What
, is the amino acid that needs to be supplemented due to a defect in what
enzyme?
Rib 2 - ,,,answer,,,..where does the posterior scalene attach to?
Paclitaxel - ,,,answer,,,..used in the treatment of breast and ovarian
cancer
MOA: hyper stabilization of polymerized microtubules--> prevents the
breakdown of the mitotic spindle
restrictive barrier - ,,,answer,,,..maximum distance a patient can actually
move a joint, can be pathologic
narcissistic personality disorder - ,,,answer,,,..patterns of grandiosity,
need for admiration, lack of empathy for others
A carotid massage causes an increase in stretch of the carotid
baroreceptors which causes a reflexive PARASYM response which slows
down the conduction velocity through the AV node this slowing down
Heart Rate--> used in paroxysmal supra ventricular tachycardia -
,,,answer,,,..what does a carotid massage do and how does it affect the
AV node?
Chronic myelogenous leukemia t(9;22)--> Philly chx - ,,,answer,,,..a form
of leukemia characterized by the accumulation of abnormal, mature
granulocytes (granulocytes are a type of white blood cell), mild anemia,
thrombocytosis and basophilia. What is the associated chromosomal
translocation?
Burkitt's lymphoma t(8;14) - ,,,answer,,,..germinal B celll lymphoma that
is associated with a translocation between c-MYC and the Ig heavy chain
on which two chromosomes? It is endemic in the continent of Africa
which produces this
