Questions with Guaranteed Pass
Solutions 2025-2026 Updated.
increasing life expectancy - Answer antibiotics have played a major role in increasing
_________ throughout the world
60-70%, methicillin-resistant S. aureus (MRSA) - Answer antibiotics may soon become useless
due to being overprescribed and misused especially in hospital setting and as many as _______
of nosocomial staphylococcus infections are the result of _________
a compound produced by one microbe that adversely affects other microbes - Answer what is
an antibiotic?
proposed that bacteria and molds engage in a perpetual battle for survival - Answer what did
Ernest Duchesne contribute to antibiotics
Ernest Duchesne - Answer proposed that bacteria and molds engage in a perpetual battle for
survival
alexander fleming - Answer who rediscovered penicillin in 1928
rediscovered penicillin in 1928, mold was identified as Penicillium notatum - Answer what
contribution did Alexander Fleming make to science?
Howard Florey and Ernst Chain - Answer in the 1940s, penicillin was purified by _______ and
_______ which saved millions of lives
purified penicillin which has saved millions of lives since - Answer what contribution did
Howard Florey and Ernst Chain make to microbiology?
1) discovered sulfa drugs (prontosil dye)
2) inactive until converted by the body to active agents
, Gerhard Domagk - Answer discovered sulfa drugs which were inactive until converted by the
body to active agents
1) discovered streptomycin
2) antibiotic produced by actinomycete bacterium found in the soil: Streptomyces griseus -
Answer what contribution did Salman Waksman make to microbiology?
Salman Waksman - Answer discovered streptomycin which is an antibiotic bacterium found in
the soil
1) antibiotic must affect target organism: drug should affect microbial physiology, that does not
exist, or is greatly modified, in humans: peptidoglycan, differences in ribosome structure,
biochemical pathway missing in humans
2) but it must NOT affect humans: many have side effects at high concentration:
chloramphenicol interferes with RBC development, some may cause allergic response - Answer
what are the two criteria for an effective antibiotic?
effective against many species (both Gram + and Gram -) - Answer broad spectrum antibiotics
broad-spectrum antibiotics - Answer effective against many species (both Gram + and Gram -)
narrow-spectrum antibiotics - Answer effective against specific bacteria
effective against specific bacteria - Answer narrow-spectrum antibiotics
bactericidal - Answer ________ antibiotics kill target organisms
bacteriostatic: cannot kill organism, immune system removes intruding microbe - Answer
_________ antibiotics prevent growth of organisms
1) the relative effectiveness of different antibiotics on the organism causing the infection
2) the average attainable tissue levels of each drug
3) minimal inhibitory concentration (MIC) - Answer when deciding on which antibiotic to
prescribe, what factors must they consider: