MSN 570 ADVANCED PATHOPHYSIOLOGY
ADVANCED PATHOPHYSIOLOGY MSN 570
FINAL EXAM 4 VERIFIED QUESTIONS AND
CORRECT DETAILED ANSWERS GRADED A+
GUARANTEED PASS (RATIONALES) |
The principle Ig mediator of type I hypersensitivity reactions is
- IgA.
- IgG.
- IgM.
- IgE. - Correct Answer :IgE
Immunoglobulin E (IgE) is the principal antibody mediating type I
hypersensitivity reactions. IgA is not the primary Ig mediator of type I
hypersensitivity reactions. IgG is involved in type II hypersensitivity reactions.
IgM is involved in type II hypersensitivity reactions.
A+ TEST BANK 1
, MSN 570 ADVANCED PATHOPHYSIOLOGY
Autoimmune diseases result from (Select all that apply.)
- overactive immune function.
- increase in self-tolerance.
- failure of the immune system to differentiate self and nonself molecules.
- communicable infections. –
Correct Answer :- overactive immune function.
- failure of the immune system to differentiate self and nonself molecules.
Autoimmunity results from a functional increase in the activity of the immune
system. Breakdown of self-tolerance occurs. Genetic and environmental factors
are thought to contribute to autoimmunity. Autoimmune disease results from
failure of the immune system to differentiate self and nonself molecules; this
results in immune reactions that attack normal tissue.
Severe combined immunodeficiency (SCID) syndrome is an example of a(n)
- deficient immune response.
- excessive immune response.
- primary acquired immunodeficiency.
- hypersensitivity reaction. - Correct Answer :deficient immune response.
SCID syndrome is an example of a deficient immune response in which the
immune response is ineffective because of disease-causing genotypes or
secondary/acquired dysfunction. An excessive immune response includes
disorders in which the immune system is overfunctioning or hyperfunctioning.
A+ TEST BANK 2
, MSN 570 ADVANCED PATHOPHYSIOLOGY
HIV/AIDS is an example of a primary acquired immunodeficiency disorder.
Hypersensitivity reactions are an excessive immune response.
Secondary immune deficiency problems may be caused by (Select all that
apply.)
- surgery.
- high blood sugar.
- corticosteroids.
- genetic disorders.
- low protein level. –
Correct Answer :- surgery.
- high blood sugar.
- corticosteroids.
- low protein level.
Surgery leads to reduced B and T-cell counts. High blood sugar decreases WBC
function. Corticosteroids are immunosuppressive. Antibodies are composed of
proteins; low protein level impairs antibody synthesis. Genetic abnormalities of
immune components lead to primary immune deficiency problems.
A primary effector cell of the type I hypersensitivity response is
- monocytes.
- mast cells.
- neutrophils.
A+ TEST BANK 3
, MSN 570 ADVANCED PATHOPHYSIOLOGY
- cytotoxic cells. –
Correct Answer :mast cells
Mast cells are a primary effector cell of the type I hypersensitivity response.
Monocytes, neutrophils, and cytotoxic cells are not primary effectors of the type
I hypersensitivity response.
When mast cells degranulate, they release:
- perforins and other toxins.
- histamine and other inflammatory mediators.
- complement.
- antibodies. –
Correct Answer :histamine and other inflammatory mediators.
Mast cells release inflammatory mediators such as histamine when they
degranulate.
How does a cytotoxic T lymphocyte kill another cell?
- By secreting cytokines that attract phagocytes
- By producing antibodies that opsonize it
- By phagocytizing it directly
- By secreting perforins and granzymes –
A+ TEST BANK 4
ADVANCED PATHOPHYSIOLOGY MSN 570
FINAL EXAM 4 VERIFIED QUESTIONS AND
CORRECT DETAILED ANSWERS GRADED A+
GUARANTEED PASS (RATIONALES) |
The principle Ig mediator of type I hypersensitivity reactions is
- IgA.
- IgG.
- IgM.
- IgE. - Correct Answer :IgE
Immunoglobulin E (IgE) is the principal antibody mediating type I
hypersensitivity reactions. IgA is not the primary Ig mediator of type I
hypersensitivity reactions. IgG is involved in type II hypersensitivity reactions.
IgM is involved in type II hypersensitivity reactions.
A+ TEST BANK 1
, MSN 570 ADVANCED PATHOPHYSIOLOGY
Autoimmune diseases result from (Select all that apply.)
- overactive immune function.
- increase in self-tolerance.
- failure of the immune system to differentiate self and nonself molecules.
- communicable infections. –
Correct Answer :- overactive immune function.
- failure of the immune system to differentiate self and nonself molecules.
Autoimmunity results from a functional increase in the activity of the immune
system. Breakdown of self-tolerance occurs. Genetic and environmental factors
are thought to contribute to autoimmunity. Autoimmune disease results from
failure of the immune system to differentiate self and nonself molecules; this
results in immune reactions that attack normal tissue.
Severe combined immunodeficiency (SCID) syndrome is an example of a(n)
- deficient immune response.
- excessive immune response.
- primary acquired immunodeficiency.
- hypersensitivity reaction. - Correct Answer :deficient immune response.
SCID syndrome is an example of a deficient immune response in which the
immune response is ineffective because of disease-causing genotypes or
secondary/acquired dysfunction. An excessive immune response includes
disorders in which the immune system is overfunctioning or hyperfunctioning.
A+ TEST BANK 2
, MSN 570 ADVANCED PATHOPHYSIOLOGY
HIV/AIDS is an example of a primary acquired immunodeficiency disorder.
Hypersensitivity reactions are an excessive immune response.
Secondary immune deficiency problems may be caused by (Select all that
apply.)
- surgery.
- high blood sugar.
- corticosteroids.
- genetic disorders.
- low protein level. –
Correct Answer :- surgery.
- high blood sugar.
- corticosteroids.
- low protein level.
Surgery leads to reduced B and T-cell counts. High blood sugar decreases WBC
function. Corticosteroids are immunosuppressive. Antibodies are composed of
proteins; low protein level impairs antibody synthesis. Genetic abnormalities of
immune components lead to primary immune deficiency problems.
A primary effector cell of the type I hypersensitivity response is
- monocytes.
- mast cells.
- neutrophils.
A+ TEST BANK 3
, MSN 570 ADVANCED PATHOPHYSIOLOGY
- cytotoxic cells. –
Correct Answer :mast cells
Mast cells are a primary effector cell of the type I hypersensitivity response.
Monocytes, neutrophils, and cytotoxic cells are not primary effectors of the type
I hypersensitivity response.
When mast cells degranulate, they release:
- perforins and other toxins.
- histamine and other inflammatory mediators.
- complement.
- antibodies. –
Correct Answer :histamine and other inflammatory mediators.
Mast cells release inflammatory mediators such as histamine when they
degranulate.
How does a cytotoxic T lymphocyte kill another cell?
- By secreting cytokines that attract phagocytes
- By producing antibodies that opsonize it
- By phagocytizing it directly
- By secreting perforins and granzymes –
A+ TEST BANK 4
