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Exam (elaborations)

Test Bank — Hematology in Practice, 2nd Edition — Betty Ciesla

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The Test Bank for Hematology in Practice, 2nd Edition by Betty Ciesla offers a complete, instructor‑oriented repository of assessment questions aligned with the textbook’s chapter layout and learning objectives. It includes multiple‑choice, true/false, short‑answer, and case‑based questions designed to assess students’ mastery of hematology principles, red cell pathology, white cell disorders, coagulation science, and laboratory methodology. Each question is mapped to specific chapters and subtopics—such as morphology, pathophysiology, diagnostic criteria, and instrumentation—to support quizzes, midterms, and final exams. The Test Bank mirrors the detailed organization of the text, beginning with Part I: Basic Hematology Principles, which includes Chapter 1: Introduction to Hematology and Basic Laboratory Practice, covering topics like microscope care, safety and quality assurance, preanalytic and postanalytic variables, delta checks, and critical values. Chapter 2: From Hematopoiesis to the Complete Blood Count explores stem cell regulation, bone marrow vs. spleen roles, erythropoiesis, red cell indices, morphology, and anemia classification. Chapter 3: Red Blood Cell Production, Function, and Relevant Red Blood Cell Morphology delves into RBC maturation, membrane structure, metabolism, and abnormal cell forms. Chapter 4: Hemoglobin Function and Principles of Hemolysis explains hemoglobin synthesis, oxygen dissociation, abnormal hemoglobins, mechanisms of hemolysis, and diagnostic markers. Part II: Red Blood Cell Disorders includes Chapter 5: The Microcytic Anemias, addressing iron deficiency, anemia of chronic disease, sideroblastic anemia, and thalassemia syndromes. Chapter 6: The Macrocytic Anemias covers megaloblastic processes, vitamin B/folate deficiency, and non‑megaloblastic macrocytosis. Chapter 7: Normochromic Anemias examines membrane defects, enzymopathies (e.g. G6PD, pyruvate kinase), and other non‑hemoglobin hemolysis. Chapter 8: Normochromic Anemias Caused by Hemoglobinopathies focuses on sickle cell disease, hemoglobin variants, and trait/compound heterozygous states. Part III: White Blood Cell Disorders features Chapter 9: Leukopoiesis and Leukopoietic Function, covering normal leukocyte development, differential counts, and lymphocyte maturation. Chapter 10: Abnormalities of White Blood Cells: Quantitative, Qualitative, and the Lipid Storage Diseases addresses leukocytosis, leukopenia, congenital white cell anomalies, functional defects, reactive changes, and storage disorders. Chapter 11: Acute Leukemias discusses classification, laboratory features, prognostic factors, and differential diagnosis. Chapter 12: Chronic Myeloproliferative Disorders addresses CML, essential thrombocythemia, polycythemia vera, idiopathic myelofibrosis, and related syndromes. Chapter 13: Lymphoproliferative Disorders and Related Plasma Cell Disorders covers leukemias, lymphomas, multiple myeloma, Waldenström’s macroglobulinemia. Chapter 14: The Myelodysplastic Syndromes explores dysplasia, classification, prognostic criteria, cytogenetics, and management. Part IV: Hemostasis and Disorders of Coagulation includes Chapter 15: Overview of Hemostasis and Platelet Physiology, covering primary/secondary hemostasis pathways, platelet function, and coagulation testing. Chapter 16: Quantitative and Qualitative Platelet Disorders reviews thrombocytopenia, thrombocytosis, platelet function defects, acquired and inherited platelet disorders. Chapter 17: Defects of Plasma Clotting Factors addresses hemophilias, congenital factor deficiencies, inhibitors, and vitamin K roles. Chapter 18: Fibrinogen, Thrombin, and the Fibrinolytic System examines fibrinogen defects, dysfibrinogenemias, thrombin’s role, fibrinolysis, and DIC. Chapter 19: Introduction to Thrombosis and Anticoagulant Therapy focuses on thrombosis pathophysiology, inherited and acquired hypercoagulable states, laboratory diagnosis, and anticoagulant/thrombolytic management. Part V: Laboratory Procedures is represented by Chapter 20: Basic Procedures in a Hematology Laboratory, which includes microhematocrit, erythrocyte sedimentation rate, manual reticulocyte counts, peripheral smear evaluation, WBC/platelet counting, coagulation assays (PT, aPTT), D-dimer testing, automation technologies, flow cytometry, mixing studies, and quality control practices.

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Hematology In Practice, 2nd Edition
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Hematology in Practice, 2nd Edition











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Institution
Hematology in Practice, 2nd Edition
Course
Hematology in Practice, 2nd Edition

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Uploaded on
October 24, 2025
Number of pages
96
Written in
2025/2026
Type
Exam (elaborations)
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STHematology in Practice –
UV
IA_ 2nd Edition
AP
TEST BANK PR
O VE
Betty Ciesla
D?
Comprehensive Test Bank for Instructors

and Students

© Betty Ciesla

All rights reserved. Reproduction or distribution without permission is prohibited.




Created by MedConnoisseur ©2025/2026

,ST
TABLE OF CONTENTS
UV
Hematology in Practice – 2nd Edition
Betty Ciesla
IA_
Part I: Basic Hematology Principles
AP
1. Introduction to Hematology and Basic Laboratory Practice
2. From Hematopoiesis to the Complete Blood Count
3. Red Blood Cell Production, Function, and Relevant Red Cell
PR
Morphology
4. Hemoglobin Function and Principles of Hemolysis

Part II: Red Blood Cell Disorders
O
5. The Microcytic Anemias
6. The Macrocytic Anemias
VE
7. Normochromic Anemias: Biochemical, Membrane, and Miscellaneous Red
Blood Cell Disorders
8. The Normochromic Anemias Caused by Hemoglobinopathies D?
Part III: White Blood Cell Disorders
9. Leukopoiesis, WBC Differential, and Lymphocyte Function
10. Abnormalities of White Blood Cells: Quantitative, Qualitative, and Storage
Diseases
11. Acute Leukemias
12. Myeloproliferative Neoplasms
13. Lymphoproliferative Disorders and Plasma Cell Disorders
14. The Myelodysplastic Syndromes

Part IV: Hemostasis and Disorders of Coagulation
15. Overview of Hemostasis and Platelet Physiology
16. Quantitative & Qualitative Platelet Disorders
17. Defects of Plasma Clotting Factors
18. Fibrinogen, Thrombin, and the Fibrinolytic System
19. Introduction to Thrombosis and Anticoagulant Therapy

Part V: Hematology Automation, Flow Cytometry & Lab Procedures
20. Hematology Automation and Flow Cell Cytometry
21. Basic Procedures in a Hematology Laboratory


Created by MedConnoisseur ©2025/2026

, ST
Chapter 1: Introduction to Hematology and Basic Laboratory Practice

Multiple Choice


____
UV
Identify the choice that best completes the statement or answers the question.

1. Tube length when referring to the microscope is the:
a. Resolution power of the objective
IA_
b. Distance from the eyepiece to the objective
c. Numerical aperture
d. Magnitude of the image on the stage

____ 2. What is the most useful corrective action for the microscope when fine details cannot be visualized
AP
in immature cells?
a. Open up diaphragm for maximum light.
b. Wipe off lenses with lens cleaner.
c. Get a new slide.


____
d. Move to a lower power.
PR
3. Which of the following behaviors is a violation of standard precautions?
a. Handwashing after glove removal
b. Use of impermeable laboratory gowns
c. Use of goggles and face shields
d. Placing laboratory notebooks on laboratory work area
OV
____ 4. Standards and calibrators differ from control materials because: ED
a. An exact amount of analyte is present in a standard or calibrator
b. A variable amount of analyte is present depending on patient samples
c. Standards only need to be within a target range
d. Standards are run to the best estimate of the known value ?
____ 5. If the confidence interval for most laboratories is 95.5%, what is the acceptable range for
hemoglobin if a hemoglobin control was run with a mean of 12.5 and a standard deviation of 1.0?
a. 9.5 to 12.5
b. 10.5 to 14.5
c. 11.5 to 15.5
d. 10.0 to 13.5
____ 6. Proper mixing of samples and timely delivery of samples to the laboratory are both examples of:
a. Delta checks
b. Postanalytic variables
c. Preanalytic variables
d. Reflex testing

____ 7. A delta check is a historical reference on samples run in the laboratories. Once a sample fails a delta
check, the most obvious corrective action is to:
a. Verify the identification of the patient sample
b. Reestablish the parameters of the delta check
c. Perform reflex testing

, ST
____
d. Perform a manual method

8. Which of the following is the definition of a reference interval?
a. A solution of a known amount of analyte
UV
b. Materials analyzed concurrently with unknown samples
c. Values established for a particular analyte, given a method, instrument, or patient
population
d. Validation techniques on flagged samples

____
IA_
9. Which of the following is not considered a postanalytic variable?
a. Delta checks
b. Proper anticoagulant used
c. Specimen checked for clots
AP
d. Critical results called

____ 10. Error analysis, standard protocols, and turnaround time are all part of the:
a. Quality assurance system
b. Quality control program
c. Reference standards
d. Delta check protocol
PR
a. Mean
b. Mode
c. Median
OV
____ 11. The average of a group of data points is defined as the:



d. Modicum ED
____ 12. Safety training is part of new employee training in health care and includes:
a. Biological hazards
b. Chemical hazards ?
c. Environmental hazards
d. All of the above

____ 13. Control materials are:
a. Analyzed concurrently with the unknown samples
b. Substances with a known amount of analyte
c. Used to calibrate the method
d. All of the above

____ 14. Delta checks are used in the hematology laboratory to:
a. Compare past patient results to the current result
b. Verify control accuracy
c. Establish a target range
d. Establish reference ranges for a particular analyte

____ 15. When handwashing after a patient contact, the soap application process should last at least:
a. 5 seconds
b. 15 seconds
c. 20 seconds

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