TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY
16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
66/COMPLETE GUIDE 2024-2025
,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a hospital client who is
having a computed tomography (CT) scan. The nursing attendant working
on the oncology unit administers chemotherapy to hospital clients who have
cancer. At the Public Health Department, a nursing attendant administers a
measles-mumps-rubella (MMR) vaccine to a 14-month-old child as a
routine immunization. Which branch of pharmacology best describes the
actions of all three
nursing attendants?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- B
Reasoning :->>>>>>
Pharmacology is the study of the biologic effects of chemicals. Nursing
attendants are involved with clinical pharmacology or pharmacotherapeutics,
which is a branch of pharmacology that deals with the uses of drugs to treat,
prevent, and diagnose disease. The radiology nursing attendant is
administering a drug to help diagnose a disease. The oncology nursing
attendant is administering a drug to help treat a disease. Pharmacoeconomics
includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.
2. When involved in phase III drug evaluation studies, what
responsibilities would the nursing attendant have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate hospital clients to be involved in the drug study
C) Monitoring and observing hospital clients closely for adverse effects
D) Conducting research to determine effectiveness of the drug
,ACCURATE CHOICE:- C
Reasoning:->>>>>>
Phase III studies involve use of a drug in a vast clinical population in which
hospital clients are asked to record any symptoms they experience while
taking the drugs. Nursing attendants may be responsible for helping collect
and analyzethe information to be shared with the Food and Drug
Administration (FDA)but would not conduct research independently
because nursing attendants donot prescribe medications. Use of animals in
drug testing is done in the preclinical trials. Select hospital clients who are
involved in phase II studies to participate in studies where the participants
have the disease the drug is intended to treat. These hospital clients are
monitored closely for drug action and adverse effects. Phase I studies
involve healthy human volunteers who are usually paid for their
participation. Nursing attendants may observe for
adverse effects and toxicity.
3. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
The nursing attendant is aware this drug has a high abuse potential. Under
what category would morphine be classified?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
ACCURATE CHOICE:- B
Reasoning:->>>>>>
Narcotics with a high abuse potential are classified as Schedule II drugs
because of severe dependence liability. Schedule I drugs have high abuse
potential and no accepted medical use. Schedule III drugs have a lesser
abuse potential than II and an accepted medical use. Schedule IV drugs have
low abuse potential and limited dependence liability.
4. What concept is considered when generic drugs are substituted for brand
name drugs?
A) Bioavailability
, Page 5 of 822
B) Critical concentration
C) Distribution
D) Half-life
ACCURATE CHOICE:-A
Reasoning:->>>>>>
Bioavailability is the portion of a dose of a drug that reaches the systemic
circulation and is available to act on body cells. Binders used in a generic
drug may not be the same as those used in the brand name drug. Therefore,
the way the body breaks down and uses the drug may differ, which may
eliminate a generic drug substitution. Critical concentration is the amount of
a drug that is needed to cause a therapeutic effect and should not differ
between generic and brand name medications. Distribution is the phase of
pharmacokinetics, which involves the movement of a drug to the bodys
tissues and is the same in generic and brand name drugs. A drugs half-life is
the time it takes for the amount of drug to decrease to half the peak level,
which should not change when substituting a generic medication.
5. A nursing attendant is assessing the hospital clients home medication use. After
listening to the hospital client list current medications, the nursing
attendant asks what priority question?
A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
C) Are these medications safe to take during pregnancy?
D) Do you take any over-the-counter medications?
ACCURATE CHOICE:- D
Reasoning:->>>>>>
It is important for the nursing attendant to specifically question use of over-
the-counter medications because hospital clients may not consider them
important. The hospital client is unlikely to know the meaning of orphan
drugs unless they too are primary health care providers. Safety during
pregnancy, use of a genericmedication, or classification of orphan drugs are
things the hospital client would be unable to answer but could be found in
reference books if the nursing attendant wishes to research them.
16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
66/COMPLETE GUIDE 2024-2025
,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a hospital client who is
having a computed tomography (CT) scan. The nursing attendant working
on the oncology unit administers chemotherapy to hospital clients who have
cancer. At the Public Health Department, a nursing attendant administers a
measles-mumps-rubella (MMR) vaccine to a 14-month-old child as a
routine immunization. Which branch of pharmacology best describes the
actions of all three
nursing attendants?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- B
Reasoning :->>>>>>
Pharmacology is the study of the biologic effects of chemicals. Nursing
attendants are involved with clinical pharmacology or pharmacotherapeutics,
which is a branch of pharmacology that deals with the uses of drugs to treat,
prevent, and diagnose disease. The radiology nursing attendant is
administering a drug to help diagnose a disease. The oncology nursing
attendant is administering a drug to help treat a disease. Pharmacoeconomics
includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.
2. When involved in phase III drug evaluation studies, what
responsibilities would the nursing attendant have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate hospital clients to be involved in the drug study
C) Monitoring and observing hospital clients closely for adverse effects
D) Conducting research to determine effectiveness of the drug
,ACCURATE CHOICE:- C
Reasoning:->>>>>>
Phase III studies involve use of a drug in a vast clinical population in which
hospital clients are asked to record any symptoms they experience while
taking the drugs. Nursing attendants may be responsible for helping collect
and analyzethe information to be shared with the Food and Drug
Administration (FDA)but would not conduct research independently
because nursing attendants donot prescribe medications. Use of animals in
drug testing is done in the preclinical trials. Select hospital clients who are
involved in phase II studies to participate in studies where the participants
have the disease the drug is intended to treat. These hospital clients are
monitored closely for drug action and adverse effects. Phase I studies
involve healthy human volunteers who are usually paid for their
participation. Nursing attendants may observe for
adverse effects and toxicity.
3. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
The nursing attendant is aware this drug has a high abuse potential. Under
what category would morphine be classified?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
ACCURATE CHOICE:- B
Reasoning:->>>>>>
Narcotics with a high abuse potential are classified as Schedule II drugs
because of severe dependence liability. Schedule I drugs have high abuse
potential and no accepted medical use. Schedule III drugs have a lesser
abuse potential than II and an accepted medical use. Schedule IV drugs have
low abuse potential and limited dependence liability.
4. What concept is considered when generic drugs are substituted for brand
name drugs?
A) Bioavailability
, Page 5 of 822
B) Critical concentration
C) Distribution
D) Half-life
ACCURATE CHOICE:-A
Reasoning:->>>>>>
Bioavailability is the portion of a dose of a drug that reaches the systemic
circulation and is available to act on body cells. Binders used in a generic
drug may not be the same as those used in the brand name drug. Therefore,
the way the body breaks down and uses the drug may differ, which may
eliminate a generic drug substitution. Critical concentration is the amount of
a drug that is needed to cause a therapeutic effect and should not differ
between generic and brand name medications. Distribution is the phase of
pharmacokinetics, which involves the movement of a drug to the bodys
tissues and is the same in generic and brand name drugs. A drugs half-life is
the time it takes for the amount of drug to decrease to half the peak level,
which should not change when substituting a generic medication.
5. A nursing attendant is assessing the hospital clients home medication use. After
listening to the hospital client list current medications, the nursing
attendant asks what priority question?
A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
C) Are these medications safe to take during pregnancy?
D) Do you take any over-the-counter medications?
ACCURATE CHOICE:- D
Reasoning:->>>>>>
It is important for the nursing attendant to specifically question use of over-
the-counter medications because hospital clients may not consider them
important. The hospital client is unlikely to know the meaning of orphan
drugs unless they too are primary health care providers. Safety during
pregnancy, use of a genericmedication, or classification of orphan drugs are
things the hospital client would be unable to answer but could be found in
reference books if the nursing attendant wishes to research them.
