Med Surg HESI V2 Exam (2025–2026 Edition) | Verified Exam
Questions & Answers | 100% Accurate | Graded A+
The Med Surg HESI V2 Exam (2025–2026 Edition) provides verified and fully updated
exam questions with accurate, expert-reviewed answers. This comprehensive study resource is
designed to help nursing students prepare for the Medical-Surgical Nursing section of the
HESI exam by reinforcing critical thinking, patient-centered care, and clinical decision-making
skills across diverse patient scenarios.
Introduction
This updated HESI V2 review includes all the major areas covered in the actual
exam—cardiovascular, respiratory, neurological, gastrointestinal, renal, endocrine,
musculoskeletal, and integumentary systems. Each question is structured to mirror
HESI testing standards, integrating NCLEX-style rationales that build test-taking confidence
and clinical judgment proficiency. The resource ensures mastery of nursing priorities, safety
measures, and evidence-based interventions for both acute and chronic patient conditions. The
HESI Med Surg V2 Exam typically consists of 55 questions, and this guide provides a full set of
55 questions to reflect the exam structure.
Answer Format
All correct answers are highlighted in bold and green, with detailed rationales explaining the
reasoning behind each solution. These explanations reinforce understanding of core nursing
concepts, pathophysiology links, pharmacological management, and priority-based
interventions. Graded A+ | Verified 2025/2026 Edition | 100% Accuracy Guaranteed.
Cardiovascular System (8 Questions)
1. A patient with acute coronary syndrome is receiving nitroglycerin IV.
What is the priority nursing assessment?
a) Blood pressure
b) Blood glucose
c) Respiratory rate
d) Pain level
a) Blood pressure
Rationale: Nitroglycerin, a vasodilator, can cause hypotension. Monitoring blood pressure is the
priority to prevent hemodynamic instability in acute coronary syndrome.
2. A patient with heart failure is prescribed spironolactone. What
electrolyte should the nurse monitor?
a) Sodium
b) Potassium
c) Calcium
, d) Magnesium
b) Potassium
Rationale: Spironolactone, a potassium-sparing diuretic, can cause hyperkalemia. Monitoring
potassium levels is essential to prevent arrhythmias.
3. A patient with a new diagnosis of atrial fibrillation is started on
amiodarone. What should the nurse teach the patient?
a) Avoid grapefruit juice
b) Increase fiber intake
c) Expect weight gain
d) Take with meals
a) Avoid grapefruit juice
Rationale: Amiodarone interacts with grapefruit juice, increasing drug levels and toxicity risk.
Patients should avoid grapefruit to ensure safe use.
4. A patient post-coronary artery bypass graft (CABG) reports chest pain.
What should the nurse do first?
a) Administer morphine
b) Notify the provider
c) Increase oxygen flow
d) Check vital signs
d) Check vital signs
Rationale: Chest pain post-CABG may indicate complications (e.g., ischemia, graft occlusion).
Checking vital signs assesses stability and guides further action.
5. A patient with deep vein thrombosis (DVT) is prescribed enoxaparin.
What should the nurse monitor?
a) Platelet count
b) Blood glucose
c) Liver function
d) Thyroid levels
a) Platelet count
Rationale: Enoxaparin, a low-molecular-weight heparin, can cause thrombocytopenia.
Monitoring platelet count ensures early detection of adverse effects.
6. A patient with hypertension reports a headache. What should the nurse
do first?
a) Administer acetaminophen
b) Check blood pressure
c) Encourage fluid intake
d) Provide a dark room
b) Check blood pressure
Rationale: A headache in a hypertensive patient may indicate a hypertensive crisis. Checking
blood pressure is the priority to assess for urgency.
Questions & Answers | 100% Accurate | Graded A+
The Med Surg HESI V2 Exam (2025–2026 Edition) provides verified and fully updated
exam questions with accurate, expert-reviewed answers. This comprehensive study resource is
designed to help nursing students prepare for the Medical-Surgical Nursing section of the
HESI exam by reinforcing critical thinking, patient-centered care, and clinical decision-making
skills across diverse patient scenarios.
Introduction
This updated HESI V2 review includes all the major areas covered in the actual
exam—cardiovascular, respiratory, neurological, gastrointestinal, renal, endocrine,
musculoskeletal, and integumentary systems. Each question is structured to mirror
HESI testing standards, integrating NCLEX-style rationales that build test-taking confidence
and clinical judgment proficiency. The resource ensures mastery of nursing priorities, safety
measures, and evidence-based interventions for both acute and chronic patient conditions. The
HESI Med Surg V2 Exam typically consists of 55 questions, and this guide provides a full set of
55 questions to reflect the exam structure.
Answer Format
All correct answers are highlighted in bold and green, with detailed rationales explaining the
reasoning behind each solution. These explanations reinforce understanding of core nursing
concepts, pathophysiology links, pharmacological management, and priority-based
interventions. Graded A+ | Verified 2025/2026 Edition | 100% Accuracy Guaranteed.
Cardiovascular System (8 Questions)
1. A patient with acute coronary syndrome is receiving nitroglycerin IV.
What is the priority nursing assessment?
a) Blood pressure
b) Blood glucose
c) Respiratory rate
d) Pain level
a) Blood pressure
Rationale: Nitroglycerin, a vasodilator, can cause hypotension. Monitoring blood pressure is the
priority to prevent hemodynamic instability in acute coronary syndrome.
2. A patient with heart failure is prescribed spironolactone. What
electrolyte should the nurse monitor?
a) Sodium
b) Potassium
c) Calcium
, d) Magnesium
b) Potassium
Rationale: Spironolactone, a potassium-sparing diuretic, can cause hyperkalemia. Monitoring
potassium levels is essential to prevent arrhythmias.
3. A patient with a new diagnosis of atrial fibrillation is started on
amiodarone. What should the nurse teach the patient?
a) Avoid grapefruit juice
b) Increase fiber intake
c) Expect weight gain
d) Take with meals
a) Avoid grapefruit juice
Rationale: Amiodarone interacts with grapefruit juice, increasing drug levels and toxicity risk.
Patients should avoid grapefruit to ensure safe use.
4. A patient post-coronary artery bypass graft (CABG) reports chest pain.
What should the nurse do first?
a) Administer morphine
b) Notify the provider
c) Increase oxygen flow
d) Check vital signs
d) Check vital signs
Rationale: Chest pain post-CABG may indicate complications (e.g., ischemia, graft occlusion).
Checking vital signs assesses stability and guides further action.
5. A patient with deep vein thrombosis (DVT) is prescribed enoxaparin.
What should the nurse monitor?
a) Platelet count
b) Blood glucose
c) Liver function
d) Thyroid levels
a) Platelet count
Rationale: Enoxaparin, a low-molecular-weight heparin, can cause thrombocytopenia.
Monitoring platelet count ensures early detection of adverse effects.
6. A patient with hypertension reports a headache. What should the nurse
do first?
a) Administer acetaminophen
b) Check blood pressure
c) Encourage fluid intake
d) Provide a dark room
b) Check blood pressure
Rationale: A headache in a hypertensive patient may indicate a hypertensive crisis. Checking
blood pressure is the priority to assess for urgency.
