CORRECT ANSWERS
in the elderly drugs distributed in water increase or decrease concentration; examples - correct answer-
increase; ETOH, lithium
in the elderly drugs distributed in fat increase or decrease concentration; examples - correct answer-
decrease; psychoactive meds
drugs distributed in fat have more or less action in those with adipose tissue - correct answer-more
higher protein binding drugs have increased or decreased risk for ADRBin lean body mass; examples -
correct answer-increased; warfarin, salicylates, dilantin
in elderly urine specific gravity - correct answer-decreases
in elderly, glucose - correct answer-decreased
in elderly urine protein - correct answer-increased
in elderly ESR; value over _______ s significant - correct answer-increased; 50
in elderly leukocytes/lymphocytes - correct answer-decreased
in elderly BUN - correct answer-increased
in elderly creatnine - correct answer-slight incrase
in elderly creatnine clearance - correct answer-decreased
,in elderly cholesterol - correct answer-increased
in elderly albumin - correct answer-decreased
consider the of medications affecting absorption - correct answer-timing
medications which can increase absorption - correct answer-slow gastric motility
these increase the risk for drug distribution changes - correct answer-dehydration and malnutrition
muscle loss is partially reversible by - correct answer-exercise
body composition changes SQ fat - correct answer-decreased
body composition changes visceral fat - correct answer-increased
max heart rate - correct answer-decreases
cardiac output depends on this in elderly, not HRB- correct answer-preload
baroreceptor function is by diuretics - correct answer-exaggerated
airway reactivity - correct answer-increases
respiratory changes oxygen level but not - correct answer-CO2
EF decrease is not considered - correct answer-normal aging
triad of doom of aging heart - correct answer-diastolic dysfunction, afib, rvr
, this may be absent with fever, blood loss, hypotension, dehydration - correct answer-tachycardia
this can impair cardiac output - correct answer-over diuresis
this can significantly elevate BP - correct answer-stress
kidney concentration and diluting capacity is - correct answer-decreased
erythropoietin production is - correct answer-unchanged until very old
cockcroft-gault formula - correct answer-[(140-
age)(weight in kg)]/[72xserum creating] multiply by 0.85 for woman
the cockcroft fault formula in debilitated patients - correct answer-overestimates creatnine clearance
modification of diet in renal disease (MDRD) formula estimates creating clearance based on -
correct answer-serum creatnine, age, race, gender
use MDRD cautiously in - correct answer-extremes in weight, age, altered body surfaces
aging predisposes to disease by - correct answer-immunocompromised state
chronic inflammatory state
hyper coagulable state
insulin resistant state
labs that increase - correct answer-alk phos
ana
crp
tot chol
clotting factors VII and VIII
copper