__ is an inhibitory neurotransmitter in lower parts of CNS
Correct Answer Glycine
___ enters an NMDA channel, when ___ is expelled from the
channel Correct Answer Ca2+
Mg2+
___ is "programmed cell death", which causes the cell to break
into multiple membreane-wrapped fragments. Does this trigger
an immune response? Correct Answer Apoptosis
No
___ is a drug that blocks GABA release Correct Answer
Tetanospasmin
___ is a drug that blocks GAD. This drug causes ___ Correct
Answer Allglycine
Seizures
___ is a drug that blocks GAT1. What is its medical use?
Correct Answer Tigabine (Gabitril)
Anticonvulsant
___ is a drug that inhibits GABA-aminotransferase. Correct
Answer Vigabatrin (Sabril)
___ is a drug used as an anticonvulsant whose mechanism of
action is unknown. Correct Answer Gaba pentin (Neurotonin)
,___ is a GABA precursor through one pathway, which may
result in overproduction of GABA Correct Answer GHB
___ is a GHB salt used to prevent cataplexy in narcoleppsy and
to treat excessive daytime sleepiness Correct Answer Xyrem
___ is a marker for GABAergic neurons Correct Answer
GABA synthesizing enzume
___ is a neurotoxin that is taken up into dopamine and nore-
epinephrein neurons, then kills the neuron. Correct Answer 6-
hydroxydopamine (6-OHDA_
___ is also to treat acromegaly (overproduction of growth
hormone) and pituitary prolactinomas (tumors of the pituitary
gland). Correct Answer Bromocriptine
___ is death due to physical or chemical insult. Does this trigger
an immune response? Correct Answer Necrosis
Yes
___ is used to treat menstual problems, and stops milk
production in both men and women. Correct Answer
Bromocriptine
___ receptors are ligand and voltage gated Correct Answer
NMDA
___ was used extensively in the 1950's as an antihypertensive
and and antipsychotic agent? What is its mechanism of action?
Correct Answer Reserpine
, It blocks dopamine storage
____ and ____ block NMDA receptors, they are glutamate
antagonists Correct Answer Phencyclidine (PCP)
Ketamine
___, the poison produced by the tetanus bacterium, blocks
release of glycine (and GABA) Correct Answer
Tetanospasmin
1 receptor activation is called a single stimulus. Multiple,
repeated stimuli are called ____. Correct Answer Tetanus
2 drugs treat psychoses by blocking D2 receptors. One is high
potency, the other is low potency. Which is which? Correct
Answer Chlorpromazine - Low potency
Haloperidol - High potency
5 drugs block NE reuptake. Which ones are NE selective, and
are DA/NE non-selective? Correct Answer Desipramine (NE
selective)
Cocaine (DA/NE)
Methylphenidate (DA/NE)
Amphetamine (DA/NE)
MDMA (DA/NE)
6-OHDA was used to study ___ syndrome, which is a rare ,
male-only disorder that consists of mental retardation and self-
mutilation Correct Answer Lesch-Nyhan
Albuteral Correct Answer Beta 2 Selective Agonist