Principles of Biochemistry Exam 1
-log [H+]= - ANS-pH
[H+][A-]
————
[HA] - ANS-Ka
<7 - ANS-Acidic pH
=7 - ANS-neutral pH
>7 - ANS-Basic pH
3-dimmensional form - ANS-Conformation
allosteric effector - ANS--binds non-covalently at regulatory web page
- modify enzyme hobby via conformational modifications
Altered by way of a trade in pH - ANS-Ionization kingdom of amino acids
Always ionized in aqueous answers
depending on pH, net fee at the molecule may be zero
internet bad rate if the pH of the answer is above its pl; it will have internet nice rate if the pH of
the answer is beneath pl - ANS-Amino acids
Amide bond between amino acids
formed by using condensation of the a-carboxyl of 1 amino acid with the a-amino of every other
amino acid - ANS-peptide bond
amino acid linear collection
the 3 dimensional structure of a protein is determined with the aid of - ANS-number one
structure
Amino acid polymers with > 50 amino acid residues - ANS-Polypeptides
Arrangement of or greater polypeptide chains into multisubunit molecule - ANS-Quaternary
structure
, Association of no polar molecules or companies with every other in aqueous structures -
ANS-Hydrophobic interactions
Between oppositely charged side chains inside the indoors of a protein also stabilize protein
shape - ANS-Charge-rate interactions
biological catalyst
generally are proteins
quickens reaction with the aid of lowering the activation power for the response
do no longer adjust G of the response - ANS-Enzymes
Can additionally be expressed as pKa = -log Ka - ANS-Ka
Capability to release H+ - ANS-Acid dissociation consistent (Ka)
Changing the fee of synthesis & degradation of enzyme (relative slow) - ANS-Control of enzyme
tiers
colloidal aggregates with the charged "head" facing outward to the water and the nonpolar "tail"
component internal - ANS-Micelles
Compounds that have the identical molecular system but differ inside the association of atoms
in space - ANS-Stereoisomers
Contain both polar & nonpolar corporations - ANS-Amphiphilic
Contain electronegative atoms (O,N,S) that gives upward push to unequal sharing of electrons
in the bonds - ANS-Polar corporations
Contributes to cooperativity of folding
enables stabilize secondary systems & native conformation - ANS-Hydrogen boding
disruption of local conformation of a protein, with lack of biological hobby by using chemical or
physical manner
retailers disrupt noncovalent bonding, ensuing in lack of tertiary & quaternary structure (every
now and then secondary)
-log [H+]= - ANS-pH
[H+][A-]
————
[HA] - ANS-Ka
<7 - ANS-Acidic pH
=7 - ANS-neutral pH
>7 - ANS-Basic pH
3-dimmensional form - ANS-Conformation
allosteric effector - ANS--binds non-covalently at regulatory web page
- modify enzyme hobby via conformational modifications
Altered by way of a trade in pH - ANS-Ionization kingdom of amino acids
Always ionized in aqueous answers
depending on pH, net fee at the molecule may be zero
internet bad rate if the pH of the answer is above its pl; it will have internet nice rate if the pH of
the answer is beneath pl - ANS-Amino acids
Amide bond between amino acids
formed by using condensation of the a-carboxyl of 1 amino acid with the a-amino of every other
amino acid - ANS-peptide bond
amino acid linear collection
the 3 dimensional structure of a protein is determined with the aid of - ANS-number one
structure
Amino acid polymers with > 50 amino acid residues - ANS-Polypeptides
Arrangement of or greater polypeptide chains into multisubunit molecule - ANS-Quaternary
structure
, Association of no polar molecules or companies with every other in aqueous structures -
ANS-Hydrophobic interactions
Between oppositely charged side chains inside the indoors of a protein also stabilize protein
shape - ANS-Charge-rate interactions
biological catalyst
generally are proteins
quickens reaction with the aid of lowering the activation power for the response
do no longer adjust G of the response - ANS-Enzymes
Can additionally be expressed as pKa = -log Ka - ANS-Ka
Capability to release H+ - ANS-Acid dissociation consistent (Ka)
Changing the fee of synthesis & degradation of enzyme (relative slow) - ANS-Control of enzyme
tiers
colloidal aggregates with the charged "head" facing outward to the water and the nonpolar "tail"
component internal - ANS-Micelles
Compounds that have the identical molecular system but differ inside the association of atoms
in space - ANS-Stereoisomers
Contain both polar & nonpolar corporations - ANS-Amphiphilic
Contain electronegative atoms (O,N,S) that gives upward push to unequal sharing of electrons
in the bonds - ANS-Polar corporations
Contributes to cooperativity of folding
enables stabilize secondary systems & native conformation - ANS-Hydrogen boding
disruption of local conformation of a protein, with lack of biological hobby by using chemical or
physical manner
retailers disrupt noncovalent bonding, ensuing in lack of tertiary & quaternary structure (every
now and then secondary)
