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Saunders NCLEX-RN Medical-Surgical Test Bank 2025 | 250+ Original Practice Questions with Rationales | Pathophysiology & Nursing Priorities

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Saunders NCLEX-RN Medical-Surgical Test Bank 2025 | 250+ Original Practice Questions with Rationales | Pathophysiology & Nursing Priorities Master the NCLEX-RN 2025 with 250+ original Saunders-style Med-Surg questions & rationales. Build clinical judgment, confidence, and test-day readiness. Ace the NCLEX-RN with Expert-Level Medical-Surgical Mastery Step into your exam fully prepared with this comprehensive, evidence-based NCLEX-RN Medical-Surgical Test Bank, expertly crafted to align with the 2025 NCLEX-RN Test Plan and the latest edition of Saunders Comprehensive Review for the NCLEX-RN Examination. This professionally formatted resource includes 250+ brand-new, original NCLEX-RN style questions that mirror the tone, structure, and cognitive level of the real exam. Each question is meticulously written by experienced nurse educators and NCLEX item writers to strengthen your clinical judgment, critical thinking, and test-taking confidence. What’s Inside 7 Major Body Systems Covered: Cardiovascular, Respiratory, Neurological, Gastrointestinal, Renal, Endocrine, and Musculoskeletal. Focus Areas: Pathophysiology, nursing priorities, laboratory interpretation, and patient education — the exact domains tested on the NCLEX-RN. Detailed Rationales: Every question includes comprehensive rationales for both correct and incorrect options, reinforcing deep understanding and long-term retention. Professional Test Bank Format: Organized for self-paced study or classroom integration, ideal for students, tutors, and nursing faculty. 2025 NCLEX-RN Alignment: Reflects current Next-Generation NCLEX (NGN) emphasis on clinical judgment, evidence-based nursing interventions, and patient-centered care. Why This Resource Works Unlike recycled question sets, this collection delivers original, high-quality items that integrate real-world nursing scenarios with rationale-based learning. Each question challenges your reasoning, interpretation, and decision-making — skills essential for modern nursing practice and NCLEX success. Whether you’re reviewing for your final semester, preparing for licensure, or teaching in a nursing education program, this resource ensures mastery across complex Med-Surg systems and patient care domains. Benefits for Nursing Students & Educators Develop critical thinking and clinical judgment through realistic case scenarios. Review essential labs, pathophysiology, and safety interventions. Perfect for independent practice, tutoring, or faculty test preparation. Boost confidence before the NCLEX-RN and improve pass rates. Authored and reviewed by nurse educators with real exam-writing expertise. Take Control of Your NCLEX Success Empower your study sessions with the precision and depth of Saunders Comprehensive Review — reimagined for next-generation NCLEX readiness. Download now and start mastering the Medical-Surgical foundations every registered nurse must know. Turn your preparation into performance, and walk into the NCLEX with total confidence. Saunders NCLEX-RN review NCLEX-RN 2025 test bank Medical-Surgical nursing questions NCLEX practice questions with rationales Saunders comprehensive review latest edition Nursing test bank Med-Surg NCLEX-RN exam prep 2025 Next Generation NCLEX questions NCLEX practice exam medical surgical Nursing student study guide Evidence-based nursing review NCLEX-RN clinical judgment practice Professional nursing test bank PDF Pathophysiology NCLEX questions NCLEX lab values review Cardiovascular respiratory renal NCLEX Endocrine and GI nursing questions Original NCLEX-RN questions Nursing educator resource NCLEX NCLEX success practice questions #NCLEXPrep #NCLEXRN #NursingStudents #NursingEducation #MedSurgNursing #SaundersReview #NextGenNCLEX #NurseEducator #NurseLife #NursingExam #NCLEXQuestions #ClinicalJudgment #FutureNurse #NursingSchool #NCLEXSuccess #TestBank #NursingResource #StudySmart #NursingRationales #NursingCommunity

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Uploaded on
October 10, 2025
Number of pages
920
Written in
2025/2026
Type
Exam (elaborations)
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Saunders Comprehensive Review for the NCLEX-PN®
Examination
9th Edition


Questions (1–20)


1 — Cardiovascular (Heart failure — pathophysiology &
priority action)
A 68-year-old man with chronic systolic heart failure (EF
30%) is admitted with increasing dyspnea, orthopnea,
and bilateral crackles. His weight has increased 4 kg in 3
days. Vital signs: BP 110/68, HR 102, RR 24, SpO₂ 91% on
room air. Which nursing action has the highest priority?
A. Teach the patient to restrict sodium to ≤2 g/day
B. Elevate the head of the bed and administer
supplemental oxygen as ordered
C. Weigh the patient daily and document intake/output
D. Administer furosemide (lasix) IV as prescribed
Correct answer: B
Rationale — Correct (B): The patient shows acute
decompensated heart failure with pulmonary congestion

,(dyspnea, orthopnea, crackles, hypoxemia). Immediate
priority is to improve oxygenation and reduce work of
breathing — elevate head of bed and give supplemental
oxygen per order. This addresses the ABCs
(airway/oxygenation) and stabilizes before other
interventions. Evidence-based nursing practice prioritizes
airway and oxygenation in cardiopulmonary compromise.
Why not A: Sodium restriction is important long-term
management but is not the immediate priority in acute
decompensation.
Why not C: Daily weights and I/O are essential for
monitoring fluid status but are monitoring actions, not
the immediate priority to relieve hypoxemia.
Why not D: IV diuretics are often indicated (and may be
next) but oxygenation/positioning must be initiated
immediately; if diuretic administration is already ordered
and available, give it promptly — however
airway/oxygenation remains the first priority action.
Teaching point: For acute pulmonary edema, position
upright, give oxygen, and follow with diuretics and other
orders to reduce preload and afterload.

,2 — Cardiovascular (Acute coronary syndrome:
recognition & priority)
A 58-year-old woman arrives with chest pressure
radiating to jaw and left arm for 45 minutes. ECG shows
ST elevation in leads V2–V4. Which nursing action is
highest priority?
A. Obtain a 12-lead ECG and administer chewable aspirin
per protocol
B. Start IV access and prepare the patient for emergent
reperfusion therapy (PCI) per facility protocol
C. Administer sublingual nitroglycerin and monitor BP
every 5 minutes
D. Give morphine for pain control and anxiety reduction
Correct answer: B
Rationale — Correct (B): ST-elevation myocardial
infarction (STEMI) requires rapid reperfusion (PCI or
fibrinolysis) to limit infarct size. Starting IV access and
preparing for emergent reperfusion is the priority to
expedite definitive treatment. Time to reperfusion
critically affects outcomes.
Why not A: Obtaining ECG and aspirin are important and
usually come earlier, but the stem already indicates ST
elevation (ECG done). The highest priority now is to

, expedite reperfusion (PCI activation). If ECG not done yet,
it would be first — but here activation/prep is top.
Why not C: Nitroglycerin can relieve ischemic pain but
may lower blood pressure and is not the key life-saving
intervention when reperfusion must be initiated urgently.
Why not D: Morphine can help pain but does not
improve survival and is not the priority over reperfusion.
Teaching: For STEMI, door-to-balloon and door-to-needle
times are critical — activate cath lab and prepare patient
(IV, consent, labs, anticoagulation as ordered).


3 — Cardiovascular (Anticoagulation education)
A patient with new atrial fibrillation is prescribed
warfarin. Which statement by the patient indicates
correct understanding of warfarin teaching?
A. “I will stop taking my aspirin now that I am on
warfarin.”
B. “I will have my INR checked regularly and keep my diet
consistent in vitamin K.”
C. “If my gums bleed, I will stop the warfarin
immediately.”
D. “I can take OTC decongestants whenever I need them.”
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