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Saunders NCLEX-RN Medical-Surgical Test Bank 2025 | 250+ Original Questions & Rationales | Pathophysiology, Labs & Nursing Priorities

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Saunders NCLEX-RN Medical-Surgical Test Bank 2025 | 250+ Original Questions & Rationales | Pathophysiology, Labs & Nursing Priorities Master the 2025 NCLEX-RN with 250+ original Saunders-style Med-Surg questions & rationales. Perfect for nursing students & educators. Test smarter, pass faster! Product Overview Take your NCLEX-RN preparation to the next level with this comprehensive Medical-Surgical Nursing Test Bank, expertly crafted from the latest edition of Saunders Comprehensive Review for the NCLEX-RN Examination. Featuring 250+ original NCLEX-style questions, this resource is meticulously aligned with the 2025 NCLEX-RN Test Plan — ensuring you study smarter, retain key concepts, and build clinical judgment with confidence. Developed by experienced nurse educators and NCLEX item writers, each question mirrors the tone, format, and difficulty of the real exam — with detailed rationales for both correct and incorrect answers to strengthen your critical thinking and clinical reasoning. What’s Inside 250+ original NCLEX-RN style Medical-Surgical questions based on Saunders Comprehensive Review (latest edition). In-depth coverage of all major body systems: Cardiovascular Respiratory Neurological Gastrointestinal Renal Endocrine Musculoskeletal Emphasis on core nursing competencies — pathophysiology, priority nursing interventions, lab interpretation, and patient education. Evidence-based rationales for both correct and incorrect options, helping you understand why — not just what. Professional test-bank formatting for educators and students — ideal for classroom integration, study groups, and individual review. Why Nursing Students & Educators Love This Resource Perfectly aligned with the 2025 NCLEX-RN Test Plan to reflect the latest exam structure and question types. Builds clinical judgment and decision-making skills, the foundation of next-generation NCLEX success. Saves study time by focusing on high-yield Med-Surg content tested most frequently on the NCLEX. Enhances confidence with rationales that explain concepts in simple, clinical terms supported by evidence-based nursing care. Versatile use: ideal for self-assessment, classroom exams, tutoring sessions, and remediation programs. Learning Outcomes By the end of this test bank, learners will be able to: Analyze patient scenarios and prioritize nursing actions using clinical judgment. Interpret laboratory values and link them to pathophysiologic processes. Identify early warning signs of complications and implement timely interventions. Educate patients effectively on treatment, medication safety, and lifestyle modifications. Apply evidence-based nursing principles confidently across all major body systems. Why Choose This Test Bank Trusted by nursing students and educators worldwide, this Saunders-based test bank combines academic rigor with practical clinical relevance. Whether you’re a first-time NCLEX candidate or an educator designing review modules, this resource delivers a complete, authentic, and exam-ready experience.

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Uploaded on
October 10, 2025
Number of pages
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Written in
2025/2026
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Saunders Comprehensive Review for the NCLEX-PN®
Examination
9th Edition


1 — Cardiovascular: Acute MI — Priority Intervention
A 62-year-old man is admitted with chest pressure radiating to
his left arm and jaw for 45 minutes. ECG shows ST-segment
elevation in leads II, III, and aVF. Blood pressure 90/56 mm Hg,
HR 110 bpm, respiratory rate 20/min, SpO₂ 96% on room air.
Which nursing action is the highest priority?
A. Administer aspirin 325 mg chewable per protocol.
B. Obtain blood for troponin and basic metabolic panel.
C. Prepare the client for emergent percutaneous coronary
intervention (PCI).
D. Give sublingual nitroglycerin.
Answer: A. Administer aspirin 325 mg chewable per protocol.
Rationale (correct): Chewable aspirin should be given
immediately in suspected acute myocardial infarction (AMI)
unless contraindicated — it inhibits platelet aggregation and
reduces early mortality. Immediate antiplatelet therapy is a
time-sensitive, evidence-based priority in STEMI care.
Rationale (incorrect):
B — Obtaining labs is important but not the single highest
priority; it should occur concurrently but after/while

,administering aspirin.
C — Preparing for PCI is essential for STEMI reperfusion, but the
nurse can and should give aspirin immediately while arranging
PCI. Timely aspirin administration is quicker and life-saving.
D — Sublingual nitroglycerin may relieve ischemic pain and
reduce preload, but it can worsen hypotension (BP 90/56); thus
nitroglycerin is contraindicated until BP stabilizes.


2 — Cardiovascular: Heart Failure — Lab Interpretation &
Teaching
A 74-year-old woman with chronic heart failure (HF) presents
with increasing dyspnea and ankle swelling. Her serum B-type
natriuretic peptide (BNP) is 980 pg/mL (normal <100),
creatinine 1.1 mg/dL, potassium 4.5 mEq/L. Which statement
by the nurse best explains the BNP result and next steps?
A. “A BNP of 980 confirms fluid overload from HF; we will likely
increase your diuretic and monitor your weight and
electrolytes.”
B. “This BNP is normal; it rules out heart failure as the cause of
your symptoms.”
C. “BNP only reflects kidney function, so we’ll consult
nephrology instead of changing your HF medications.”
D. “A high BNP means your ejection fraction is normal; no
changes are needed.”

,Answer: A. “A BNP of 980 confirms fluid overload from HF; we
will likely increase your diuretic and monitor your weight and
electrolytes.”
Rationale (correct): Elevated BNP correlates with ventricular
stretch and is commonly used to support HF diagnosis and
assess severity. A value of 980 is consistent with
decompensated HF. Diuretic adjustment and close monitoring
of weight, urine output, and electrolytes (K⁺, creatinine) are
evidence-based interventions.
Rationale (incorrect):
B — BNP 980 is markedly elevated and does not rule out HF; it
supports it.
C — BNP is influenced by both cardiac and renal function but
primarily indicates cardiac ventricular stress; nephrology
referral may be needed if renal issues arise, but primary HF
management is indicated.
D — BNP does not indicate ejection fraction being normal; high
BNP usually suggests volume/pressure overload and warrants
treatment.


3 — Cardiovascular: Anticoagulation Education
A client with new atrial fibrillation is prescribed warfarin. Which
statement by the client indicates correct understanding of
discharge teaching?

, A. “I’ll keep my vitamin K intake consistent and have regular INR
checks.”
B. “I’ll stop taking warfarin before dental cleanings without
telling anyone.”
C. “I can take aspirin on my own whenever I have a headache.”
D. “I don’t need to report any increased bruising; it’s normal.”
Answer: A. “I’ll keep my vitamin K intake consistent and have
regular INR checks.”
Rationale (correct): Warfarin’s effect is influenced by dietary
vitamin K; consistent intake and regular INR monitoring are
essential to maintain therapeutic anticoagulation and reduce
risk of bleeding or thrombosis.
Rationale (incorrect):
B — Stopping warfarin without provider guidance risks
thrombosis; dental procedures may require coordinated
management.
C — Adding aspirin increases bleeding risk; the client should
consult the prescriber before taking antiplatelets.
D — Increased bruising could indicate over-anticoagulation; the
client must report bleeding signs promptly.


4 — Cardiovascular: Post-Op CABG Priority Assessment
A client returns to the post-anesthesia care unit after coronary
artery bypass grafting (CABG). Which assessment finding
requires immediate intervention?
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