CSPI for Specialists in Poison
Information Exam
**Question 1.** Which phase of toxicokinetics involves the movement
of a toxicant from the site of exposure into the bloodstream?
A) Absorption
B) Distribution
C) Metabolism
D) Excretion
**Answer:** A) Absorption
**Explanation:** Absorption is the process by which a substance enters
the bloodstream from the site of contact, such as the gastrointestinal
tract, skin, or lungs.
**Question 2.** Which mechanism of toxicodynamics describes how a
chemical interacts with cellular receptors to produce a biological effect?
,CSPI for Specialists in Poison
Information Exam
A) Dose-response relationship
B) Mechanism of action
C) Toxicokinetics
D) Risk assessment
**Answer:** B) Mechanism of action
**Explanation:** The mechanism of action explains how a toxicant
interacts with cellular components, such as receptors, to produce toxic
effects.
**Question 3.** In risk assessment, which step involves estimating the
probability of adverse health effects from exposure to a toxicant?
A) Hazard identification
B) Dose-response assessment
,CSPI for Specialists in Poison
Information Exam
C) Risk characterization
D) Exposure assessment
**Answer:** C) Risk characterization
**Explanation:** Risk characterization combines hazard identification,
dose-response, and exposure assessments to estimate health risks.
**Question 4.** Which classification of poisons is based on their ability
to produce systemic effects through absorption?
A) Local irritants
B) Systemic poisons
C) Corrosives
D) Sensitizers
**Answer:** B) Systemic poisons
, CSPI for Specialists in Poison
Information Exam
**Explanation:** Systemic poisons are absorbed and distributed to
cause effects at sites distant from the point of entry.
**Question 5.** What is the primary role of a poison control center
(PCC)?
A) Conducting toxicology research
B) Providing immediate, expert poison information and management
advice
C) Regulating chemical safety standards
D) Performing chemical analysis in laboratories
**Answer:** B) Providing immediate, expert poison information and
management advice
**Explanation:** PCCs serve as accessible resources for healthcare
providers and the public for rapid poison management guidance.
Information Exam
**Question 1.** Which phase of toxicokinetics involves the movement
of a toxicant from the site of exposure into the bloodstream?
A) Absorption
B) Distribution
C) Metabolism
D) Excretion
**Answer:** A) Absorption
**Explanation:** Absorption is the process by which a substance enters
the bloodstream from the site of contact, such as the gastrointestinal
tract, skin, or lungs.
**Question 2.** Which mechanism of toxicodynamics describes how a
chemical interacts with cellular receptors to produce a biological effect?
,CSPI for Specialists in Poison
Information Exam
A) Dose-response relationship
B) Mechanism of action
C) Toxicokinetics
D) Risk assessment
**Answer:** B) Mechanism of action
**Explanation:** The mechanism of action explains how a toxicant
interacts with cellular components, such as receptors, to produce toxic
effects.
**Question 3.** In risk assessment, which step involves estimating the
probability of adverse health effects from exposure to a toxicant?
A) Hazard identification
B) Dose-response assessment
,CSPI for Specialists in Poison
Information Exam
C) Risk characterization
D) Exposure assessment
**Answer:** C) Risk characterization
**Explanation:** Risk characterization combines hazard identification,
dose-response, and exposure assessments to estimate health risks.
**Question 4.** Which classification of poisons is based on their ability
to produce systemic effects through absorption?
A) Local irritants
B) Systemic poisons
C) Corrosives
D) Sensitizers
**Answer:** B) Systemic poisons
, CSPI for Specialists in Poison
Information Exam
**Explanation:** Systemic poisons are absorbed and distributed to
cause effects at sites distant from the point of entry.
**Question 5.** What is the primary role of a poison control center
(PCC)?
A) Conducting toxicology research
B) Providing immediate, expert poison information and management
advice
C) Regulating chemical safety standards
D) Performing chemical analysis in laboratories
**Answer:** B) Providing immediate, expert poison information and
management advice
**Explanation:** PCCs serve as accessible resources for healthcare
providers and the public for rapid poison management guidance.
