USMLE Step 2 CK: Chronic Hepatitis C Treatment Criteria
and Management With complete solution– Expert Verified |
Latest Questions 2025
What is the primary factor that determines the decision to treat chronic hepatitis
C (HCV) patients? - The decision to treat HCV patients depends on multiple factors
including age, detectable serum HCV RNA, compensated liver disease, stable
laboratory studies, and liver biopsy findings.
What are the widely accepted criteria for initiating treatment in chronic hepatitis
C patients? - Criteria include age >18, detectable HCV RNA in serum, liver biopsy
showing bridging fibrosis or worse, compensated liver disease (INR <1.5, bilirubin
<1.5 g/dL, albumin >3.4 mg/dL, no ascites), stable laboratory studies, willingness
to be treated, and no contraindications.
What is the initial therapy for treatment-naive HCV patients? - Initial therapy
includes peginterferon plus ribavirin.
Why is combination therapy preferred over monotherapy in treating HCV? -
Combination therapy has been shown to be more beneficial than monotherapy
with either peginterferon or ribavirin.
What additional medication is given to HCV patients with genotype 1? - Patients
with HCV genotype 1 receive an additional protease inhibitor, either telaprevir or
boceprevir.
How is HCV viral load monitored during treatment? - HCV viral load is typically
monitored to assess the response to treatment.
and Management With complete solution– Expert Verified |
Latest Questions 2025
What is the primary factor that determines the decision to treat chronic hepatitis
C (HCV) patients? - The decision to treat HCV patients depends on multiple factors
including age, detectable serum HCV RNA, compensated liver disease, stable
laboratory studies, and liver biopsy findings.
What are the widely accepted criteria for initiating treatment in chronic hepatitis
C patients? - Criteria include age >18, detectable HCV RNA in serum, liver biopsy
showing bridging fibrosis or worse, compensated liver disease (INR <1.5, bilirubin
<1.5 g/dL, albumin >3.4 mg/dL, no ascites), stable laboratory studies, willingness
to be treated, and no contraindications.
What is the initial therapy for treatment-naive HCV patients? - Initial therapy
includes peginterferon plus ribavirin.
Why is combination therapy preferred over monotherapy in treating HCV? -
Combination therapy has been shown to be more beneficial than monotherapy
with either peginterferon or ribavirin.
What additional medication is given to HCV patients with genotype 1? - Patients
with HCV genotype 1 receive an additional protease inhibitor, either telaprevir or
boceprevir.
How is HCV viral load monitored during treatment? - HCV viral load is typically
monitored to assess the response to treatment.
