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Exam (elaborations)

PANCE Exam B Part 2 – Rosh Review Practice Questions

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Preparing for the PANCE Exam B Part 2 can feel overwhelming, but the right tools make all the difference. With Rosh Review practice questions, detailed explanations, and targeted study strategies, you can strengthen your knowledge and build confidence for exam day. This resource is designed to help physician assistant students master key topics, review high‑yield content, and practice in a format that mirrors the real exam. Whether you’re looking for a PANCE study guide, online practice test, or exam prep tips, this guide brings everything together to support your success.

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October 8, 2025
Number of pages
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Written in
2025/2026
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PANCE Exam B Part 2 – Rosh Review Practice Questions




Hyperlipidemia

Although this particular patient has normal levels of
HDL and triglycerides, his LDL is above the normal


1. chronic adrenal insufficiency

Cushing syndrom vs dz
related to SClC

& Hyperparathyroidism vs Hy-
poparathyroidism

2. ---



3. A 40-year-old man presents for an
annual health maintenance check.
His physical exam is unremarkable.
The following lab values were ob-

tained: white blood cells 8,300/mcL, limits (85-125 mg/dL), meeting criteria for hyper-


, PANCE Exam B Part 2 – Rosh Review Practice Questions

hemoglobin 16.1 g/dL, hemat- lipidemia. Total cholesterol levels over 200 mg/dL or
ocrit 45%, platelets 220,000/mcL, triglycerides over 150 mg/dL also meet criteria for the
high-density lipoprotein 45 mg/dL, diagnosis.
low-density lipoprotein 140 mg/dL,
triglycerides 148 mg/dL. Which of

the following is the most likely diag- -----------------------------------------------------------------
nosis? Hypertriglyceridemia (D) is defined by levels of triglyc-
AAnemia of chronic disease erides over 150 mg/dL. This patient's levels are below
BChronic myeloid leukemia that. Triglycerides are the most abundant fatty mole-
CHyperlipidemia cules in most organisms. When abnormally high, they
DHypertriglyceridemia are a risk factor for heart disease.

Anemia of chronic disease (A) is characterized by the
presence of a chronic inflammatory condition (e.g.
cancer, rheumatoid arthritis, infection) and a micro-
cytic or normocytic anemia and low reticulocyte count.






, PANCE Exam B Part 2 – Rosh Review Practice Questions

Serum iron transferrin is typically low to normal, while
ferritin can be normal or elevated. This patient's he-
moglobin and hematocrit are normal and he does not
have a history or signs of an inflammatory condition.

Chronic myeloid leukemia (B) is an insidious blood-cell
cancer (myeloproliferative disorder) that begins in the
bone marrow. White blood cell counts are typically
quite high, ranging from 100,000 to 500,000/mcL. This
patient's count is in the normal range.




4. A 56-year-old man with a 10-year White blood cell count 18,000
history of alcohol use disorder pre-
sents to the emergency room with dx: Acute pancreatitis
nausea and dull, epigastric pain that
Sx: epigastric pain radiating to the back, worse when
radiates to the back for the past 2
hours. Which of the following lab lying down and better when leaning forward, nausea,
values is associated with a poor and vomiting
Caused by gallstones > alcohol, hypertriglyceridemia,

prognosis for the suspected diagno-
drugs
sis?
Treatment is IV fluids, analgesics
AAspartate aminotransferase 200
Complications: necrotizing pancreatitis, pancreatic
units/L
pseudocyst, pseudoaneurysm
BGlucose 172 mg/dL
CSerum lactate dehydrogenase 300
units/L Ranson's criteria is used to assess the severity of illness
DWhite blood cell count 18,000 and % mortality. If 3 or more of the criteria are met,
there is an increased risk for pancreatic necrosis.



, PANCE Exam B Part 2 – Rosh Review Practice Questions

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