Please check the examination details below before entering your candidate information
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel Level 3 GCE
Friday 13 June 2025
Morning (Time: 2
hours)
Paper
referenc 9BN0/02
e
Biology A (Salters Nuffield) 🟐 🟐
Advanced
PAPER 2: Energy, Exercise and Coordination
You must have: Total Marks
Scientific calculator, pencil, ruler
Pearson Edexcel Level 3 GCE Biology A (Salters Nuffied) Advanced PAPER 2: Energy, Exercise and Coordination
QP JUNE 2025
Instructions
• Use black ink or ball-point pen.
• name, the
Fill in boxes at the top of this page with your
centre number and candidate number.
• Answer all
• Show your working in any calculation questions and include
units in your answer where appropriate.
• questions.
Answer the questions in the spaces
provided – there may be more space
than you need.
Information
• The total mark for this paper is 100.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each
• question. You may use a scientific calculator.
• Instructure
question(s) marked with an asterisk (*), marks will be awarded for your ability to
your answer logically showing how the points that you make are
related or follow on from each other where appropriate.
Advice
• Read each question carefully before you start to
• answer it. Try to answer every question.
• Check your answers if you have time at the Turn over
end.
P78658A
©2025 Pearson
Education Ltd. Y:1/1/1/1/
,
, Answer ALL questions. Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If you
AREA
DO NOT WRITE IN THIS
change your mind about an answer, put a line through the box and
then mark your new answer with a cross .
1 The pancreas is an organ found in the human body.
The pancreas is made up of a number of different cell types including beta
cells and acinar cells.
(a) The diagram shows a beta cell from a human pancreas.
pair of centrioles
AREA
DO NOT WRITE IN THIS
rough endoplasmic reticulum
(rER) of width 20 nm
(i) Calculate the magnification of this
diagram. (2) AREA
DO NOT WRITE IN THIS
Answer ..............................................................
2
■■■
■
, (ii) A student viewed the diagram and stated that the
cell was undergoing mitosis.
Give two reasons why this statement is correct.
(2)
DO NOT WRITE IN THIS
1 ............ ........... ........... ........... .......... ........... ........... ........... ........... ........... ........... ...... .......... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ....... .................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ............. ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... .... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
AREA
2 ............ ........... ........... ........... .......... ........... ........... ........... ........... ........... ........... ...... .......... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ....... .................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ............. ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... .... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
(b) Acinar cells produce the digestive enzyme elastase. Elastase is secreted
from the acinar cells as a glycoprotein.
The polypeptide chain for elastase is formed on the ribosomes of the rER.
Describe how this polypeptide is processed to form a glycoprotein
DO NOT WRITE IN THIS
and then released from the cell.
(4)
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
AREA
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
DO NOT WRITE IN THIS
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
AREA
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
(Total for Question 1 = 8 marks)
3
■■■ Turn
■ over
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel Level 3 GCE
Friday 13 June 2025
Morning (Time: 2
hours)
Paper
referenc 9BN0/02
e
Biology A (Salters Nuffield) 🟐 🟐
Advanced
PAPER 2: Energy, Exercise and Coordination
You must have: Total Marks
Scientific calculator, pencil, ruler
Pearson Edexcel Level 3 GCE Biology A (Salters Nuffied) Advanced PAPER 2: Energy, Exercise and Coordination
QP JUNE 2025
Instructions
• Use black ink or ball-point pen.
• name, the
Fill in boxes at the top of this page with your
centre number and candidate number.
• Answer all
• Show your working in any calculation questions and include
units in your answer where appropriate.
• questions.
Answer the questions in the spaces
provided – there may be more space
than you need.
Information
• The total mark for this paper is 100.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each
• question. You may use a scientific calculator.
• Instructure
question(s) marked with an asterisk (*), marks will be awarded for your ability to
your answer logically showing how the points that you make are
related or follow on from each other where appropriate.
Advice
• Read each question carefully before you start to
• answer it. Try to answer every question.
• Check your answers if you have time at the Turn over
end.
P78658A
©2025 Pearson
Education Ltd. Y:1/1/1/1/
,
, Answer ALL questions. Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If you
AREA
DO NOT WRITE IN THIS
change your mind about an answer, put a line through the box and
then mark your new answer with a cross .
1 The pancreas is an organ found in the human body.
The pancreas is made up of a number of different cell types including beta
cells and acinar cells.
(a) The diagram shows a beta cell from a human pancreas.
pair of centrioles
AREA
DO NOT WRITE IN THIS
rough endoplasmic reticulum
(rER) of width 20 nm
(i) Calculate the magnification of this
diagram. (2) AREA
DO NOT WRITE IN THIS
Answer ..............................................................
2
■■■
■
, (ii) A student viewed the diagram and stated that the
cell was undergoing mitosis.
Give two reasons why this statement is correct.
(2)
DO NOT WRITE IN THIS
1 ............ ........... ........... ........... .......... ........... ........... ........... ........... ........... ........... ...... .......... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ....... .................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ............. ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... .... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
AREA
2 ............ ........... ........... ........... .......... ........... ........... ........... ........... ........... ........... ...... .......... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ....... .................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ............. ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... .... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
(b) Acinar cells produce the digestive enzyme elastase. Elastase is secreted
from the acinar cells as a glycoprotein.
The polypeptide chain for elastase is formed on the ribosomes of the rER.
Describe how this polypeptide is processed to form a glycoprotein
DO NOT WRITE IN THIS
and then released from the cell.
(4)
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
AREA
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
DO NOT WRITE IN THIS
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
AREA
......... ........... ........... ........... .......... ........... ........... ........... ........... ........... ............ ........ ...... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ........... ......................
(Total for Question 1 = 8 marks)
3
■■■ Turn
■ over