Health
Primary Amenorrhea labs - CORRECT ANSWER-The initial endocrine evaluation
should include serum FSH, LH, PRL, total and free testosterone, TSH, FT4, and beta-
hCG (pregnancy test).
Girls who have a normal uterus and high FSH without the classic features of Turner
syndrome may require a karyotype to diagnose X chromosome mosaicism
Primary Amenorrhea - CORRECT ANSWER-The failure of any menses to appear is
termed "primary amenorrhea," and evaluation is commenced either (1) at age 14 years
if neither menarche nor any breast development has occurred or if height is in the
lowest 3% for ethnicity, or (2) at age 16 years if menarche has not occurred
Secondary Amenorrhea - CORRECT ANSWER-Secondary amenorrhea is defined as
the absence of menses for 3 consecutive months in women who have passed
menarche.
Primary Amenorrhea symptoms and physical exam - CORRECT ANSWER-Patients
with primary amenorrhea require a thorough history and physical examination to look for
signs of the conditions noted above. Headaches or visual field abnormalities implicate a
hypothalamic or pituitary tumor. Signs of pregnancy may be present. Blood pressure
elevation, acne, and hirsutism should be noted. Short stature may be seen with an
associated GH or thyroid hormone deficiency. Short stature with manifestations of
gonadal dysgenesis indicates Turner syndrome. Olfactory deficits are seen in Kallmann
syndrome. Obesity and short stature may be signs of Cushing syndrome. Tall stature
may be due to eunuchoidism or acromegaly. Hirsutism or virilization suggests excessive
testosterone.
An external pelvic examination plus a rectal examination should be performed to assess
hymen patency and the presence of a uterus.
Secondary Amenorrhea labs - CORRECT ANSWER-thyroid function tests, prolactin,
FSH, LH, total testosterone, serum estradiol, Pregnancy test
ACS and ACOG guidelines 21-29 years - CORRECT ANSWER-ACS start at 25:
Primary HPV alone q 5 years or
co-testing q 5 years or
cytology alone q 3 years
ACOG start at 21:
, cytology alone q 3 years
ACS and ACOG guidelines 30-65 years - CORRECT ANSWER-ACS:
Primary HPV testing alone q 5 years or
co-testing q 5 years or
cytology alone q 3 years
ACOG:
co-testing q 5 years or
cytology alone q 3 years or
primary HPV testing alone q 5 years
Pap and HPV testing over 65 years - CORRECT ANSWER-not recommended and not
recommended if hysterectomy
Bethesda Classification - CORRECT ANSWER-Squamous cell abnormalities
ASCUS - CORRECT ANSWER-· ASCUS - atypical squamous cells of undetermined
significance
· LSIL OR LGSIL - CORRECT ANSWER-· LSIL OR LGSIL - low grade squamous
intraepithelial lesion
o CIN 1: HPV or mild dysplasia
· HSIL or HGSIL - CORRECT ANSWER-· HSIL or HGSIL - high grade squamous
intraepithelial lesion
o CIN 2: moderate dysplasia
o CIN 3: severe dysplasia
Changes in glandular cells (AGCUS), presence of endometrial cells, adenocarcinoma,
etc. recommends? - CORRECT ANSWER-· Need endometrial bx
Pap Infection treatment? - CORRECT ANSWER-Infection: treatment based on
causative agent; repeat PSP 3-4 months after treatment
· For specific abnormal findings such as ASCUS - CORRECT ANSWER-· For specific
abnormal findings such as ASCUS
o HPV testing
o Repeat PSP smear
o Colposcopy
If CIN 2, 3, or CIS? - CORRECT ANSWER-Refer out
Vulvovaginitis - CORRECT ANSWER-Vulvovaginitis one of the most common causes of
vulvovaginal itching and discharge. It is characterized by