A blood pattern from a patient with a high titer cold agglutinin, which of the following effects can
occur within the presence of a chilly agglutinin?
A. Improved MCV and decreased RBC
B. Expanded MCV and normal RBC
C. Reduced MCV and improved MCHC
D. Reduced MCV and RBC - ANS-D. MCV and RBC
A function morphologic feature in hemoglobin C disorder is:
A. Macrocytosis
B. Spherocytosis
C. Rouleax formation
D. Target cells - ANS-D. Goal cells
A not unusual source of interference in the cyanmethehemoglobin technique is:
A. Hemolysis
B. Very excessive WBC count number
C. Cold agglutinins
D. Clumped platelets - ANS-B. Very excessive WBC count
A affected person has a congenital nonspherocytic hemolytic anemia. After exposure to
anti-malarial pills, the patient studies a severe hemolytic episode. This episode is characterised
with the aid of purple cellular inclusions because of hemoglobin denaturation. Which of the
subsequent conditions is maximum constant with those findings?
A. G-6-PD deficiency
B. Thalassemia fundamental
C. Pyruvate kinase deficiency
D. Paroxysmal nocturnal hemoglobinuria - ANS-A. G-6-PD deficiency
A affected person has a high bloodless agglutinin titer. Automated mobile counter
consequences display an multiplied MCV, MCH, MCHC. Individual erythrocytes appear normal
on a stained smear, but agglutinates are noted. The appropriate course of action would be to:
A. Perform the RBC, Hgb, Hct determinations using manual strategies
B. Perform the RBC willpower via a guide method; use the automated outcomes for the Hgb
and Hct
C. Repeat the determinations using a microsample of diluted blood
, D. Repeat the determinations the use of a prewarmed microsample of diluted blood - ANS-D.
Repeat the determinations the use of a prewarmed microsample of diluted blood
A affected person has the following laboratory outcomes:
RBC: 2.00 x 10^6/uL (2.00 x 10^12/L)
Hct: 24%
Hgb: 6.8 g/dL (68 g/L)
Reticulocytes: 0.Eight%
The mean corpuscular volume (MCV) of the patient is:
A. 35 um^3 (35 fL)
B. 83 um^three (83 fL)
C. A hundred and twenty um^3 (a hundred and twenty fL)
D. 150 um^three (150 fL) - ANS-C. 120 um^3 (one hundred twenty fL)
A purple blood cell approximately five um in diameter that stains shiny pink and shows no
imperative pallor is a:
A. Spherocyte
B. Leptocyte
C. Microcyte
D. Macrocyte - ANS-A. Spherocyte
A screening take a look at for paroxysmal nocturnal hemoglobinuria is:
A. Heat instability take a look at
B. Sucrose hemolysis
C. Osmotic fragility
D. Dithionite solubility - ANS-B. Sucrose hemolysis
After elimination of red blood cells from the movement hemoglobin is broken down into:
A. Iron, porphyrin, and amino acids
B. Iron, protoporphyrin, and globin
C. Heme, protoporphyrin, and amino acids
D. Heme, hemoseridin, and globin - ANS-B. Iron, protoporphyrin, and globin
An enzyme deficiency assciated with mild to sever hemolytic anemia after the patient is
exposed to certain capsules and characteristized by way of crimson mobile inclusions fashioned
by using denatured hemoglobin is:
A. Lactate dehydrogenase deficiency
B. G-6-PD deficiency
C. Pyruvate kinase deficiency