INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION
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by Susan M Ford
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, Chapter 01: General Principles of Pharmacology
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Ford: Introductory Clinical Pharmacology 12th Edition
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1. Afterteachingagroupof studentsaboutthebasics ofpharmacology, thestudents will be able to
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choose which aspect as the most critical to remember?
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A) Drug name r
B) Drug class r
C) Drug action r
D) Drug source r
Answer: C r
Rationale: Pharmacology is the study of drugs and its action on living organisms.
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rThus, an essential aspect of pharmacology is drug action. An understanding of the drug
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name, drug class, and drug source is important, but the most critical aspect related to
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rpharmacology is how the drug acts in the body. r r r r r r r r
Question Format: Multiple Choice r r r
Chapter: 1
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Learning Objective: 1 r r
Cognitive Level: Apply
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Client Needs: Physiological Integrity: Pharmacological Therapies
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Integrated Process: Teaching/Learning
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Reference: p. 3, Introduction r r r
2. A nurse suspects the client had an adverse reaction to a prescribed medication due to an
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interaction with an unreported over-the-counter supplement. Which action by the nurse
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will best assist in preventing future similar incidents?
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A) File a report with MedWatch r r r r
B) File a report with the State Board of Nursing
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C) Instruct the client to avoid combining medications in the future
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D) Document the incident and report it to the health care provider r r r r r r r r r r
Answer: A r
Rationale: Nurses play an important role in monitoring for adverse reactions. Therefore, it is
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important to submit reports, even if there is uncertainty about the cause–effect relationship.
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The FDA protects the identity of those who voluntarily report adverse reactions.
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Question Format: Multiple Choice r r r
Chapter: 1
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Learning Objective: 9 r r
Cognitive Level: Apply
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, Client Needs: Safe and Effective Care Environment: Safety and InfectionControl
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Integrated Process: Clinical Problem-solving Process (Nursing
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rProcess) Reference: p. 7, Box 1.1 MedWatch and Reporting Adverse
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rEvents
3. A nurse is assessing a client and notes the client has developed swelling of the
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reyelids and lips after administration of a prescribed medication. What does the nurse
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rinterpret this finding to specifically indicate?r r r r r
A) Mild allergic reaction r r
B) Anaphylactic shock r
C) Angioedema
D) Drug idiosyncrasy r
Answer: C r
Rationale: Angioedema is a type of allergic drug reaction manifested by the collection of
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fluid in the subcutaneous tissues, most commonly affecting the eyelids, lips, mouth, and
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throat. Allergic reactions can be manifested by a wide range of signs and symptoms such
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ras itching, rashes, and hives. Anaphylactic shock is a serious allergic reaction that
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requires immediate medical attention. Drugidiosyncrasydescribes anyunusual or abnormal
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reaction to a drug, one that is different from the one normally expected.
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Question Format: Multiple Choice r r r
rChapter: 1 r
Learning Objective: 5 r r
rCognitive Level: Apply r r
Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated
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rProcess: Clinical Problem-solving Process (Nursing Process) Reference: p. 12,
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rAllergic Drug Reactions r r
4. The nurse is preparing to teach a client about a new drug which is in the fourth phase of
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rdevelopment. Which activity will the nurse explain best illustrates this phase? r r r r r r r r r r
A) Health care providers report adverse effects to FDA. r r r r r r r
B) Healthy volunteers are involved in thetest. r r r r r r
C) In vitro tests are performed using human cells.
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D) The drug is given to clients with thedisease.
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Answer: A r
, Rationale: The postmarketing surveillance phase of drug development encourages health care
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professionals to report adverse effects of drugs to the FDA using MedWatch. Phase 1 of
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clinical testing involves 20 to 100 healthy volunteers. In vitro testing of the drug
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ron human or animal cells is done in the pre-FDA phase. In Phase 2 of clinical testing, the drug is
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given to clients with the disease for which the drug is manufactured.
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Question Format: Multiple Choice r r r
rChapter: 1 r
Learning Objective: 4 r r
rCognitive Level: Apply r r
Client Needs: Health Promotion and Maintenance
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rIntegrated Process: Teaching/Learning Reference: p. 7, r r r r r
rConcept Mastery Alert r r
5. A nurse is assessing a pregnant client who admits to having a cocaine addiction.
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rWhich condition of the baby after birth should the nurse explain and preparethe
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rclient for? r
A) Diabetes
B) Hypertension
C) Addiction to drugs r r
D) CNS defects r
Answer: C r
Rationale: The nurse informs the client that children born to mothers using addictive drugs
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rare often born with an addiction to the drug. Children born to mothers who are addicted to
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rcocaine are not known to be born with diabetes, CNS defects, or hypertension.
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Question Format: Multiple Choice r r r
rChapter: 1 r
Learning Objective: 6 r r
rCognitive Level: Apply r r
Client Needs: Health Promotion and Maintenance
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rIntegrated Process: Teaching/Learning r r
Reference: p. 11, Drug Use, Pregnancy, and Lactation r r r r r r r
6. A client arrives at the health care clinic and reports taking several pills for a
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rheadacheand severe cough without relief. Which adverse effect should the nurse be
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raware may develop from this combination?
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A) Gastrointestinal bleeding r
B) Breathing difficulties r
C) Liver damage r
D) Anaphylaxis