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Exam (elaborations)

MCN 538 Exam 2 Study Guide UPDATED 2025

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Risk Factors for Cardiovascular Disease (CVD) Modifiable: Smoking, hypertension, hyperlipidemia, obesity, sedentary lifestyle, poor diet, diabetes. Non-modifiable: Age, family history, early menopause, ethnicity. Gender-specific factors: Pregnancy-related conditions (gestational diabetes, preeclampsia), hormone therapy, polycystic ovary syndrome (PCOS). ACE Inhibitors e.g., lisinopril: Side effect - dry cough, hyperkalemia. ARBs e.g., losartan: Side effect - dizziness, hyperkalemia. Calcium Channel Blockers e.g., amlodipine: Side effect - peripheral edema, constipation. Beta-blockers e.g., metoprolol: Side effect - bradycardia, fatigue. Diuretics e.g., hydrochlorothiazide: Side effect - electrolyte imbalances, dehydration. Factors in Treating Hypertension Race: African Americans respond better to thiazide diuretics and calcium channel blockers. Co-morbidities: Diabetes, CKD, coronary artery disease (CAD) require specific treatment approaches. ACE inhibitors or ARBs are preferred for patients with diabetes or CKD. Criteria for Diagnosis of Metabolic Syndrome Requires 3 or more of the following: Abdominal obesity (waist circumference 35 inches in women), Triglycerides ≥150 mg/dL, HDL 50 mg/dL in women, Blood pressure ≥130/85 mm Hg, Fasting glucose ≥100 mg/dL. Statins e.g., atorvastatin: Adverse effect - muscle pain, liver dysfunction. Fibrates e.g., fenofibrate: Adverse effect - gallstones, myopathy. Niacin

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MCN 538



MCN 538 Exam 2 Study Guide UPDATED 2025
Risk Factors for Cardiovascular Disease (CVD)
Modifiable: Smoking, hypertension, hyperlipidemia, obesity, sedentary lifestyle,
poor diet, diabetes. Non-modifiable: Age, family history, early menopause,
ethnicity. Gender-specific factors: Pregnancy-related conditions (gestational
diabetes, preeclampsia), hormone therapy, polycystic ovary syndrome (PCOS).




ACE Inhibitors
e.g., lisinopril: Side effect - dry cough, hyperkalemia.




ARBs
e.g., losartan: Side effect - dizziness, hyperkalemia.




Calcium Channel Blockers
e.g., amlodipine: Side effect - peripheral edema, constipation.




Beta-blockers
e.g., metoprolol: Side effect - bradycardia, fatigue.




MCN 538

, MCN 538


Diuretics
e.g., hydrochlorothiazide: Side effect - electrolyte imbalances, dehydration.




Factors in Treating Hypertension
Race: African Americans respond better to thiazide diuretics and calcium channel
blockers. Co-morbidities: Diabetes, CKD, coronary artery disease (CAD) require
specific treatment approaches. ACE inhibitors or ARBs are preferred for patients
with diabetes or CKD.




Criteria for Diagnosis of Metabolic Syndrome
Requires 3 or more of the following: Abdominal obesity (waist circumference >35
inches in women), Triglycerides ≥150 mg/dL, HDL <50 mg/dL in women, Blood
pressure ≥130/85 mm Hg, Fasting glucose ≥100 mg/dL.




Statins
e.g., atorvastatin: Adverse effect - muscle pain, liver dysfunction.




Fibrates
e.g., fenofibrate: Adverse effect - gallstones, myopathy.




Niacin


MCN 538

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