TEST BANK For Psychopharmacology Drugs the Brain and Behavior 4th Edition By Meyer Nursing, Verified Chapters 1 - 20

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Test Bank rr



to accompany
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Psychopharmacology, Third Edition rr rr



Meyer • Quenzer rr rr




Chapter1: Principles of Pharmacology r rr rr rr




Multiple Choice rr




1. refer(s) to specific molecular changes that occur when a drug binds to a rr rr rr rr rr rr rr rr rr rr rr rr



particular target site or receptor, while
rr arethe resultingwidespreadalterations
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in function.
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a. Drugaction; therapeutic effects
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b. Sideeffects; drug effects
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c. Therapeutic effects; side effects r rr rr



d. Drug action; drug effects rr rr rr



Answer: d rr



Textbook Reference: Pharmacology: TheScience of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is free
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to bind at specific target sites is referred to as
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a. thetherapeutic dose.
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b. first-pass effects. rr



c. bioavailability.
d. ED50.
Answer: c rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target
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site or receptor are referred to as
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a. drug effects. rr



b. drug action. rr



c. sideeffects. r



d. placebo effects. rr



Answer: b rr



Textbook Reference: Pharmacology: TheScience of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning rr



b. Geneticvariation
c. Drug competition rr



d. Expectation of outcome rr rr



Answer: c rr



Textbook Reference: Pharmacology: TheScience of Drug Action
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Page 1 of 247
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,5. The administration of oxytocin has been proposed as a treatment for autism. rr rr rr rr rr rr rr rr rr rr



a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
rr rr rr rr r rr




6. Whichfactor does not affect the pharmacokinetics of a drug?
r rr rr rr rr rr rr rr rr



a. Route of administration rr rr



b. Lipid solubility rr



c. Depot binding rr



d. Drug action rr



Answer: d rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken rr rr rr rr rr r



a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
rr rr rr rr r rr




8. Thearea postrema is one area in the brain where the
r rr is not complete. rr rr rr rr rr rr rr rr rr rr



a. cerebrospinal fluid rr



b. blood–brain barrier rr



c. choroid plexus rr



d. phospholipid membrane rr



Answer: b rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
rr rr rr rr r rr




9. First-pass metabolism occurs with orallyadministered drugs because
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a. their absorption is slowed by food.
r rr rr rr rr



b. drugs absorbed into the bloodstream from the stomach go to the liver on the
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way to general circulation.
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c. drugs must first survive the acidic environment of the stomach.
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d. salivaryenzymes in the mouth begin the process of metabolism.
r rr rr rr rr rr rr rr rr



Answer: b rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
rr rr rr rr r rr




10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. rr



b. choroid plexus. rr



c. area postrema.
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d. median eminence. rr




Page 2 of 247
rr rr rr

, Answer: c rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
rr rr rr rr r rr




11. Drugs administered _ havethe most rapid onset of action.
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a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
rr rr rr rr r rr




12. Ionization of a drug depends on the of the solution and the
rr rr rr rr rr rr rr rr rr rr ofthe
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drug.
rr


a. pH; pKarr



b. pKa; pH rr



c. concentration; lipid solubility rr rr



d. pH; concentration
rr



Answer: a rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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13. Theabsorption of a drug depends on all of the following except
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a. lipid solubility.
rr



b. ionization.
c. body temperature.rr



d. the concentration of the drug.
rr rr rr rr



Answer: c rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highlylipid-soluble r



Answer: a rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
rr rr rr rr rr rr rr rr r rr



a. psychoactive drugs. rr



b. illicit drugs. rr



c. teratogens.
d. placental drugs. rr



Answer: c rr



Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugs
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a. bind to their target sites.
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Page 3 of 247
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